-
1
-
-
43049135853
-
-
Donnan, G. A., Fisher, M., Macleod, M., and Davis, S. M. (2008) Stroke Lancet 371, 1612-1623
-
(2008)
Stroke Lancet
, vol.371
, pp. 1612-1623
-
-
Donnan, G.A.1
Fisher, M.2
Macleod, M.3
Davis, S.M.4
-
2
-
-
65549098614
-
Apoptotic mechanisms after cerebral ischemia
-
Broughton, B. R., Reutens, D. C., and Sobey, C. G. (2009) Apoptotic mechanisms after cerebral ischemia. Stroke 40, e331-339
-
(2009)
Stroke
, vol.40
, pp. e331-339
-
-
Broughton, B.R.1
Reutens, D.C.2
Sobey, C.G.3
-
3
-
-
79960141471
-
The immunology of stroke: From mechanisms to translation
-
Iadecola, C., and Anrather, J. (2011) The immunology of stroke: from mechanisms to translation. Nat. Med. 17, 796-808
-
(2011)
Nat. Med.
, vol.17
, pp. 796-808
-
-
Iadecola, C.1
Anrather, J.2
-
4
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton, P. (1999) Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
5
-
-
33947331063
-
NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
-
Liu, Y., Wong, T. P., Aarts, M., Rooyakkers, A., Liu, L., Lai, T. W., Wu, D. C., Lu, J., Tymianski, M., Craig, A. M., and Wang, Y. T. (2007) NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J. Neurosci. 27, 2846-2857
-
(2007)
J. Neurosci.
, vol.27
, pp. 2846-2857
-
-
Liu, Y.1
Wong, T.P.2
Aarts, M.3
Rooyakkers, A.4
Liu, L.5
Lai, T.W.6
Wu, D.C.7
Lu, J.8
Tymianski, M.9
Craig, A.M.10
Wang, Y.T.11
-
6
-
-
73949090103
-
Inflammation in neurodegenerative diseases
-
Amor, S., Puentes, F., Baker, D., and van der Valk, P. (2010) Inflammation in neurodegenerative diseases. Immunology 129, 154-169
-
(2010)
Immunology
, vol.129
, pp. 154-169
-
-
Amor, S.1
Puentes, F.2
Baker, D.3
Van Der Valk, P.4
-
7
-
-
79959999864
-
Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia
-
Xiong, X., Barreto, G. E., Xu, L., Ouyang, Y. B., Xie, X., and Giffard, R. G. (2011) Increased brain injury and worsened neurological outcome in interleukin-4 knockout mice after transient focal cerebral ischemia. Stroke 42, 2026-2032
-
(2011)
Stroke
, vol.42
, pp. 2026-2032
-
-
Xiong, X.1
Barreto, G.E.2
Xu, L.3
Ouyang, Y.B.4
Xie, X.5
Giffard, R.G.6
-
8
-
-
79551633839
-
Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke
-
Ziegler, G., Freyer, D., Harhausen, D., Khojasteh, U., Nietfeld, W., and Trendelenburg, G. (2011) Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke. J. Cereb. Blood Flow Metab. 31, 757-766
-
(2011)
J. Cereb. Blood Flow Metab.
, vol.31
, pp. 757-766
-
-
Ziegler, G.1
Freyer, D.2
Harhausen, D.3
Khojasteh, U.4
Nietfeld, W.5
Trendelenburg, G.6
-
9
-
-
0038506990
-
Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke
-
Zhang, L., Zhang, Z. G., Zhang, R. L., Lu, M., Krams, M., and Chopp, M. (2003) Effects of a selective CD11b/CD18 antagonist and recombinant human tissue plasminogen activator treatment alone and in combination in a rat embolic model of stroke. Stroke 34, 1790-1795
-
(2003)
Stroke
, vol.34
, pp. 1790-1795
-
-
Zhang, L.1
Zhang, Z.G.2
Zhang, R.L.3
Lu, M.4
Krams, M.5
Chopp, M.6
-
10
-
-
26444459796
-
Neuroinflammation and both cytotoxic and vasogenic edema are reduced in interleukin-1 type 1 receptor-deficient mice conferring neuroprotection
-
Lazovic, J., Basu, A., Lin, H. W., Rothstein, R. P., Krady, J. K., Smith, M. B., and Levison, S. W. (2005) Neuroinflammation and both cytotoxic and vasogenic edema are reduced in interleukin-1 type 1 receptor-deficient mice conferring neuroprotection. Stroke 36, 2226-2231
-
(2005)
Stroke
, vol.36
, pp. 2226-2231
-
-
Lazovic, J.1
Basu, A.2
Lin, H.W.3
Rothstein, R.P.4
Krady, J.K.5
Smith, M.B.6
Levison, S.W.7
-
11
-
-
0142259734
-
Macrophage migration inhibitory factor: A regulator of innate immunity
-
Calandra, T., and Roger, T. (2003) Macrophage migration inhibitory factor: a regulator of innate immunity. Nat. Rev. Immunol. 3, 791-800
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 791-800
-
-
Calandra, T.1
Roger, T.2
-
12
-
-
0027442237
-
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia
-
Bernhagen, J., Calandra, T., Mitchell, R. A., Martin, S. B., Tracey, K. J., Voelter, W., Manogue, K. R., Cerami, A., and Bucala, R. (1993) MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature 365, 756-759
-
(1993)
Nature
, vol.365
, pp. 756-759
-
-
Bernhagen, J.1
Calandra, T.2
Mitchell, R.A.3
Martin, S.B.4
Tracey, K.J.5
Voelter, W.6
Manogue, K.R.7
Cerami, A.8
Bucala, R.9
-
13
-
-
0033571182
-
A proinflammatory cytokine inhibits p53 tumor suppressor activity
-
Hudson, J. D., Shoaibi, M. A., Maestro, R., Carnero, A., Hannon, G. J., and Beach, D. H. (1999) A proinflammatory cytokine inhibits p53 tumor suppressor activity. J. Exp. Med. 190, 1375-1382
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1375-1382
-
-
Hudson, J.D.1
Shoaibi, M.A.2
Maestro, R.3
Carnero, A.4
Hannon, G.J.5
Beach, D.H.6
-
14
-
-
0034626730
-
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
-
Kleemann, R., Hausser, A., Geiger, G., Mischke, R., Burger-Kentischer, A., Flieger, O., Johannes, F. J., Roger, T., Calandra, T., Kapurniotu, A., Grell, M., Finkelmeier, D., Brunner, H., and Bernhagen, J. (2000) Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature 408, 211-216
-
(2000)
Nature
, vol.408
, pp. 211-216
-
-
Kleemann, R.1
Hausser, A.2
Geiger, G.3
Mischke, R.4
Burger-Kentischer, A.5
Flieger, O.6
Johannes, F.J.7
Roger, T.8
Calandra, T.9
Kapurniotu, A.10
Grell, M.11
Finkelmeier, D.12
Brunner, H.13
Bernhagen, J.14
-
15
-
-
0037039308
-
Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response
-
Mitchell, R. A., Liao, H., Chesney, J., Fingerle-Rowson, G., Baugh, J., David, J., and Bucala, R. (2002) Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response. Proc. Natl. Acad. Sci. U. S. A. 99, 345-350
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 345-350
-
-
Mitchell, R.A.1
Liao, H.2
Chesney, J.3
Fingerle-Rowson, G.4
Baugh, J.5
David, J.6
Bucala, R.7
-
16
-
-
38349013153
-
The role of macrophage migration inhibitory factor in the cascade of events leading to reperfusioninduced inflammatory injury and lethality
-
Amaral, F. A., Fagundes, C. T., Guabiraba, R., Vieira, A. T., Souza, A. L., Russo, R. C., Soares, M. P., Teixeira, M. M., and Souza, D. G. (2007) The role of macrophage migration inhibitory factor in the cascade of events leading to reperfusioninduced inflammatory injury and lethality. Am. J. Pathol. 171, 1887-1893
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 1887-1893
-
-
Amaral, F.A.1
Fagundes, C.T.2
Guabiraba, R.3
Vieira, A.T.4
Souza, A.L.5
Russo, R.C.6
Soares, M.P.7
Teixeira, M.M.8
Souza, D.G.9
-
17
-
-
38749137749
-
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
-
Miller, E. J., Li, J., Leng, L., McDonald, C., Atsumi, T., Bucala, R., and Young, L. H. (2008) Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature 451, 578-582
-
(2008)
Nature
, vol.451
, pp. 578-582
-
-
Miller, E.J.1
Li, J.2
Leng, L.3
McDonald, C.4
Atsumi, T.5
Bucala, R.6
Young, L.H.7
-
18
-
-
79952369026
-
Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress
-
Koga, K., Kenessey, A., Powell, S., Sison, C. P., Miller, E. J., and Ojamaa, K. (2011) Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress. Antioxid. Redox Signal. 14, 1191-1202
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 1191-1202
-
-
Koga, K.1
Kenessey, A.2
Powell, S.3
Sison, C.P.4
Miller, E.J.5
Ojamaa, K.6
-
19
-
-
0141446025
-
A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIFlike biological functions
-
Nguyen, M. T., Beck, J., Lue, H., Funfzig, H., Kleemann, R., Koolwijk, P., Kapurniotu, A., and Bernhagen, J. (2003) A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIFlike biological functions. J. Biol. Chem. 278, 33654-33671
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33654-33671
-
-
Nguyen, M.T.1
Beck, J.2
Lue, H.3
Funfzig, H.4
Kleemann, R.5
Koolwijk, P.6
Kapurniotu, A.7
Bernhagen, J.8
-
20
-
-
0347927255
-
The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis
-
Nguyen, M. T., Lue, H., Kleemann, R., Thiele, M., Tolle, G., Finkelmeier, D., Wagner, E., Braun, A., and Bernhagen, J. (2003) The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis. J. Immunol. 170, 3337-3347
-
(2003)
J. Immunol.
, vol.170
, pp. 3337-3347
-
-
Nguyen, M.T.1
Lue, H.2
Kleemann, R.3
Thiele, M.4
Tolle, G.5
Finkelmeier, D.6
Wagner, E.7
Braun, A.8
Bernhagen, J.9
-
21
-
-
62449299177
-
Upregulation of macrophage migration inhibitory factor gene expression in stroke
-
Wang, L., Zis, O., Ma, G., Shan, Z., Zhang, X., Wang, S., Dai, C., Zhao, J., Lin, Q., Lin, S., and Song, W. (2009) Upregulation of macrophage migration inhibitory factor gene expression in stroke. Stroke 40, 973-976
-
(2009)
Stroke
, vol.40
, pp. 973-976
-
-
Wang, L.1
Zis, O.2
Ma, G.3
Shan, Z.4
Zhang, X.5
Wang, S.6
Dai, C.7
Zhao, J.8
Lin, Q.9
Lin, S.10
Song, W.11
-
22
-
-
79959642545
-
Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after stroke
-
Inacio, A. R., Bucala, R., and Deierborg, T. (2011) Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after stroke. J. Neuroinflammation 8, 75
-
(2011)
J. Neuroinflammation
, vol.8
, pp. 75
-
-
Inacio, A.R.1
Bucala, R.2
Deierborg, T.3
-
23
-
-
79953269823
-
Macrophage migration inhibitory factor promotes cell death and aggravates neurologic deficits after experimental stroke
-
Inacio, A. R., Ruscher, K., Leng, L., Bucala, R., and Deierborg, T. (2011) Macrophage migration inhibitory factor promotes cell death and aggravates neurologic deficits after experimental stroke. J. Cereb. Blood Flow Metab. 31, 1093-1106
-
(2011)
J. Cereb. Blood Flow Metab.
, vol.31
, pp. 1093-1106
-
-
Inacio, A.R.1
Ruscher, K.2
Leng, L.3
Bucala, R.4
Deierborg, T.5
-
24
-
-
0027972744
-
Cloning the human gene for macrophage migration inhibitory factor (MIF)
-
Paralkar, V., and Wistow, G. (1994) Cloning the human gene for macrophage migration inhibitory factor (MIF). Genomics 19, 48-51
-
(1994)
Genomics
, vol.19
, pp. 48-51
-
-
Paralkar, V.1
Wistow, G.2
-
25
-
-
7344230483
-
MIF expression in the rat brain: Implications for neuronal function
-
Bacher, M., Meinhardt, A., Lan, H. Y., Dhabhar, F. S., Mu, W., Metz, C. N., Chesney, J. A., Gemsa, D., Donnelly, T., Atkins, R. C., and Bucala, R. (1998) MIF expression in the rat brain: implications for neuronal function. Mol. Med. 4, 217-230
-
(1998)
Mol. Med.
, vol.4
, pp. 217-230
-
-
Bacher, M.1
Meinhardt, A.2
Lan, H.Y.3
Dhabhar, F.S.4
Mu, W.5
Metz, C.N.6
Chesney, J.A.7
Gemsa, D.8
Donnelly, T.9
Atkins, R.C.10
Bucala, R.11
-
26
-
-
0028305693
-
The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor
-
Calandra, T., Bernhagen, J., Mitchell, R. A., and Bucala, R. (1994) The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor. J. Exp. Med. 179, 1895-1902
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1895-1902
-
-
Calandra, T.1
Bernhagen, J.2
Mitchell, R.A.3
Bucala, R.4
-
27
-
-
0032230294
-
Transcriptional activation of the macrophage migration-inhibitory factor gene by the corticotropin-releasing factor is mediated by the cyclic adenosine 3=,5=- monophosphate responsive element-binding protein CREB in pituitary cells
-
Waeber, G., Thompson, N., Chautard, T., Steinmann, M., Nicod, P., Pralong, F. P., Calandra, T., and Gaillard, R. C. (1998) Transcriptional activation of the macrophage migration-inhibitory factor gene by the corticotropin-releasing factor is mediated by the cyclic adenosine 3=,5=- monophosphate responsive element-binding protein CREB in pituitary cells. Mol. Endocrinol. 12, 698-705
-
(1998)
Mol. Endocrinol.
, vol.12
, pp. 698-705
-
-
Waeber, G.1
Thompson, N.2
Chautard, T.3
Steinmann, M.4
Nicod, P.5
Pralong, F.P.6
Calandra, T.7
Gaillard, R.C.8
-
28
-
-
33746369144
-
Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1
-
Baugh, J. A., Gantier, M., Li, L., Byrne, A., Buckley, A., and Donnelly, S. C. (2006) Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1. Biochem. Biophys. Res. Commun. 347, 895-903
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.347
, pp. 895-903
-
-
Baugh, J.A.1
Gantier, M.2
Li, L.3
Byrne, A.4
Buckley, A.5
Donnelly, S.C.6
-
29
-
-
33845710642
-
HIF1alpha delays premature senescence through the activation of MIF
-
Welford, S. M., Bedogni, B., Gradin, K., Poellinger, L., Broome Powell, M., and Giaccia, A. J. (2006) HIF1alpha delays premature senescence through the activation of MIF. Genes Dev. 20, 3366-3371
-
(2006)
Genes Dev.
, vol.20
, pp. 3366-3371
-
-
Welford, S.M.1
Bedogni, B.2
Gradin, K.3
Poellinger, L.4
Broome Powell, M.5
Giaccia, A.J.6
-
30
-
-
0026970404
-
Nuclear factor kappa B: An oxidative stress-responsive transcription factor of eukaryotic cells (a review)
-
Schreck, R., Albermann, K., and Baeuerle, P. A. (1992) Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review). Free Radic. Res. Commun. 17, 221-237
-
(1992)
Free Radic. Res. Commun.
, vol.17
, pp. 221-237
-
-
Schreck, R.1
Albermann, K.2
Baeuerle, P.A.3
-
31
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle, P. A., and Henkel, T. (1994) Function and activation of NF-kappa B in the immune system. Annu. Rev. Immunol. 12, 141-179
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
32
-
-
34250847115
-
The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain
-
Stockley, J. H., and O'Neill, C. (2007) The proteins BACE1 and BACE2 and beta-secretase activity in normal and Alzheimer's disease brain. Biochem. Soc. Trans. 35, 574-576
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 574-576
-
-
Stockley, J.H.1
O'neill, C.2
-
33
-
-
84856428468
-
Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
-
Chen, C. H., Zhou, W., Liu, S., Deng, Y., Cai, F., Tone, M., Tone, Y., Tong, Y., and Song, W. (2012) Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease. Int. J. Neuropsychopharmacol. 15, 77-90
-
(2012)
Int. J. Neuropsychopharmacol.
, vol.15
, pp. 77-90
-
-
Chen, C.H.1
Zhou, W.2
Liu, S.3
Deng, Y.4
Cai, F.5
Tone, M.6
Tone, Y.7
Tong, Y.8
Song, W.9
-
34
-
-
20944444768
-
Oxidative stress potentiates BACE1 gene expression and Abeta generation
-
Tong, Y., Zhou, W., Fung, V., Christensen, M. A., Qing, H., Sun, X., and Song, W. (2005) Oxidative stress potentiates BACE1 gene expression and Abeta generation. J. Neural. Transm. 112, 455-469
-
(2005)
J. Neural. Transm.
, vol.112
, pp. 455-469
-
-
Tong, Y.1
Zhou, W.2
Fung, V.3
Christensen, M.A.4
Qing, H.5
Sun, X.6
Song, W.7
-
35
-
-
0032587072
-
NF-kappaB is activated and promotes cell death in focal cerebral ischemia
-
Schneider, A., Martin-Villalba, A., Weih, F., Vogel, J., Wirth, T., and Schwaninger, M. (1999) NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat. Med. 5, 554-559
-
(1999)
Nat. Med.
, vol.5
, pp. 554-559
-
-
Schneider, A.1
Martin-Villalba, A.2
Weih, F.3
Vogel, J.4
Wirth, T.5
Schwaninger, M.6
-
36
-
-
59349107204
-
NF-kappaB signaling in cerebral ischemia
-
Ridder, D. A., and Schwaninger, M. (2009) NF-kappaB signaling in cerebral ischemia. Neuroscience 158, 995-1006
-
(2009)
Neuroscience
, vol.158
, pp. 995-1006
-
-
Ridder, D.A.1
Schwaninger, M.2
-
37
-
-
0033913058
-
Apoptotic and antiapoptotic mechanisms in stroke
-
Mattson, M. P., Culmsee, C., and Yu, Z. F. (2000) Apoptotic and antiapoptotic mechanisms in stroke. Cell Tissue Res. 301, 173-187
-
(2000)
Cell Tissue Res.
, vol.301
, pp. 173-187
-
-
Mattson, M.P.1
Culmsee, C.2
Yu, Z.F.3
-
38
-
-
0029874138
-
The NF-kappa B and i kappa B proteins: New discoveries and insights
-
Baldwin, A. S., Jr. (1996) The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol. 14, 649-683
-
(1996)
Annu. Rev. Immunol.
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
39
-
-
0028834881
-
Rel/NF-kappa B/I kappa B story
-
Miyamoto, S., and Verma, I. M. (1995) Rel/NF-kappa B/I kappa B story. Adv. Cancer Res. 66, 255-292
-
(1995)
Adv. Cancer Res.
, vol.66
, pp. 255-292
-
-
Miyamoto, S.1
Verma, I.M.2
-
40
-
-
0041837487
-
Early NFkappaB activation is inhibited during focal cerebral ischemia in interleukin-1beta-converting enzyme deficient mice
-
Huang, F. P., Wang, Z. Q., Wu, D. C., Schielke, G. P., Sun, Y., and Yang, G. Y. (2003) Early NFkappaB activation is inhibited during focal cerebral ischemia in interleukin-1beta-converting enzyme deficient mice. J. Neurosci. Res. 73, 698-707
-
(2003)
J. Neurosci. Res.
, vol.73
, pp. 698-707
-
-
Huang, F.P.1
Wang, Z.Q.2
Wu, D.C.3
Schielke, G.P.4
Sun, Y.5
Yang, G.Y.6
-
41
-
-
41749106911
-
SP1 regulates a human SNAP-25 gene expression
-
Cai, F., Chen, B., Zhou, W., Zis, O., Liu, S., Holt, R. A., Honer, W. G., and Song, W. (2008) SP1 regulates a human SNAP-25 gene expression. J. Neurochem. 105, 512-523
-
(2008)
J. Neurochem.
, vol.105
, pp. 512-523
-
-
Cai, F.1
Chen, B.2
Zhou, W.3
Zis, O.4
Liu, S.5
Holt, R.A.6
Honer, W.G.7
Song, W.8
-
42
-
-
33646244775
-
Leaky scanning and reinitiation regulate BACE1 gene expression
-
Zhou, W., and Song, W. (2006) Leaky scanning and reinitiation regulate BACE1 gene expression. Mol. Cell. Biol. 26, 3353-3364
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3353-3364
-
-
Zhou, W.1
Song, W.2
-
43
-
-
84873802341
-
Inhibition of GSK3beta-mediated BACE1 expression reduces Alzheimer-associated phenotypes
-
Ly, P. T., Wu, Y., Zou, H., Wang, R., Zhou, W., Kinoshita, A., Zhang, M., Yang, Y., Cai, F., Woodgett, J., and Song, W. (2013) Inhibition of GSK3beta-mediated BACE1 expression reduces Alzheimer-associated phenotypes. J. Clin. Invest. 123, 224-235
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 224-235
-
-
Ly, P.T.1
Wu, Y.2
Zou, H.3
Wang, R.4
Zhou, W.5
Kinoshita, A.6
Zhang, M.7
Yang, Y.8
Cai, F.9
Woodgett, J.10
Song, W.11
-
44
-
-
84856459283
-
Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease
-
Chen, C. H., Zhou, W., Liu, S., Deng, Y., Cai, F., Tone, M., Tone, Y., Tong, Y., and Song, W. (2011) Increased NF-kappaB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease. Int. J. Neuropsychopharmacol. 18, 1-14
-
(2011)
Int. J. Neuropsychopharmacol.
, vol.18
, pp. 1-14
-
-
Chen, C.H.1
Zhou, W.2
Liu, S.3
Deng, Y.4
Cai, F.5
Tone, M.6
Tone, Y.7
Tong, Y.8
Song, W.9
-
45
-
-
84863336321
-
Hypoxia regulation of ATP13A2 (PARK9) gene transcription
-
Xu, Q., Guo, H., Zhang, X., Tang, B., Cai, F., Zhou, W., and Song, W. (2012) Hypoxia regulation of ATP13A2 (PARK9) gene transcription. J. Neurochem. 122, 251-259
-
(2012)
J. Neurochem.
, vol.122
, pp. 251-259
-
-
Xu, Q.1
Guo, H.2
Zhang, X.3
Tang, B.4
Cai, F.5
Zhou, W.6
Song, W.7
-
46
-
-
26444448943
-
Role for macrophage migration inhibitory factor in asthma
-
Mizue, Y., Ghani, S., Leng, L., McDonald, C., Kong, P., Baugh, J., Lane, S. J., Craft, J., Nishihira, J., Donnelly, S. C., Zhu, Z., and Bucala, R. (2005) Role for macrophage migration inhibitory factor in asthma. Proc. Natl. Acad. Sci. U. S. A. 102, 14410-14415
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 14410-14415
-
-
Mizue, Y.1
Ghani, S.2
Leng, L.3
McDonald, C.4
Kong, P.5
Baugh, J.6
Lane, S.J.7
Craft, J.8
Nishihira, J.9
Donnelly, S.C.10
Zhu, Z.11
Bucala, R.12
-
47
-
-
0022545394
-
A model of focal ischemic stroke in the rat: Reproducible extensive cortical infarction
-
Chen, S. T., Hsu, C. Y., Hogan, E. L., Maricq, H., and Balentine, J. D. (1986) A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 17, 738-743
-
(1986)
Stroke
, vol.17
, pp. 738-743
-
-
Chen, S.T.1
Hsu, C.Y.2
Hogan, E.L.3
Maricq, H.4
Balentine, J.D.5
-
48
-
-
33746549926
-
BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome
-
Sun, X., He, G., and Song, W. (2006) BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome. FASEB J. 20, 1369-1376
-
(2006)
FASEB J.
, vol.20
, pp. 1369-1376
-
-
Sun, X.1
He, G.2
Song, W.3
-
49
-
-
0034061930
-
Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia
-
Stephenson, D., Yin, T., Smalstig, E. B., Hsu, M. A., Panetta, J., Little, S., and Clemens, J. (2000) Transcription factor nuclear factor-kappa B is activated in neurons after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 20, 592-603
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 592-603
-
-
Stephenson, D.1
Yin, T.2
Smalstig, E.B.3
Hsu, M.A.4
Panetta, J.5
Little, S.6
Clemens, J.7
-
50
-
-
64349101903
-
Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival
-
Niizuma, K., Endo, H., and Chan, P. H. (2009) Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival. J. Neurochem. 109(Suppl. 1), 133-138
-
(2009)
J. Neurochem.
, vol.109
, pp. 133-138
-
-
Niizuma, K.1
Endo, H.2
Chan, P.H.3
-
51
-
-
84899065409
-
Macrophage migration inhibitory factor in myocardial ischaemia/reperfusion injury
-
Rassaf, T., Weber, C., and Bernhagen, J. (2014) Macrophage migration inhibitory factor in myocardial ischaemia/reperfusion injury. Cardiovasc. Res. 102, 321-328
-
(2014)
Cardiovasc. Res.
, vol.102
, pp. 321-328
-
-
Rassaf, T.1
Weber, C.2
Bernhagen, J.3
-
52
-
-
77953618805
-
Temporal and spatial differences of multiple protein expression in the ischemic penumbra after transient MCAO in rats
-
Zhang, X., Deguchi, K., Yamashita, T., Ohta, Y., Shang, J., Tian, F., Liu, N., Panin, V. L., Ikeda, Y., Matsuura, T., and Abe, K. (2010) Temporal and spatial differences of multiple protein expression in the ischemic penumbra after transient MCAO in rats. Brain Res. 1343, 143-152
-
(2010)
Brain Res.
, vol.1343
, pp. 143-152
-
-
Zhang, X.1
Deguchi, K.2
Yamashita, T.3
Ohta, Y.4
Shang, J.5
Tian, F.6
Liu, N.7
Panin, V.L.8
Ikeda, Y.9
Matsuura, T.10
Abe, K.11
-
53
-
-
84881257480
-
CAMP-response element-binding protein (CREB) and NF-kappaB transcription factors are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1
-
Nakayama, K. (2013) cAMP-response element-binding protein (CREB) and NF-kappaB transcription factors are activated during prolonged hypoxia and cooperatively regulate the induction of matrix metalloproteinase MMP1. J. Biol. Chem. 288, 22584-22595
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 22584-22595
-
-
Nakayama, K.1
-
54
-
-
65549107435
-
Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues
-
Bakirtzi, K., Belfort, G., Lopez-Coviella, I., Kuruppu, D., Cao, L., Abel, E. D., Brownell, A. L., and Kandror, K. V. (2009) Cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues. J. Neurosci. 29, 5193-5201
-
(2009)
J. Neurosci.
, vol.29
, pp. 5193-5201
-
-
Bakirtzi, K.1
Belfort, G.2
Lopez-Coviella, I.3
Kuruppu, D.4
Cao, L.5
Abel, E.D.6
Brownell, A.L.7
Kandror, K.V.8
-
55
-
-
79952369026
-
Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress
-
Koga, K., Kenessey, A., Powell, S. R., Sison, C. P., Miller, E. J., and Ojamaa, K. (2011) Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress. Antioxid. Redox Signal. 14, 1191-1202
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 1191-1202
-
-
Koga, K.1
Kenessey, A.2
Powell, S.R.3
Sison, C.P.4
Miller, E.J.5
Ojamaa, K.6
-
56
-
-
33748201552
-
Mitochondria-targeted peptide antioxidants: Novel neuroprotective agents
-
Szeto, H. H. (2006) Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J. 8, E521-E531
-
(2006)
AAPS J.
, vol.8
, pp. E521-E531
-
-
Szeto, H.H.1
-
57
-
-
27744530222
-
ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis
-
Al-Abed, Y., Dabideen, D., Aljabari, B., Valster, A., Messmer, D., Ochani, M., Tanovic, M., Ochani, K., Bacher, M., Nicoletti, F., Metz, C., Pavlov, V. A., Miller, E. J., and Tracey, K. J. (2005) ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis. J. Biol. Chem. 280, 36541-36544
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36541-36544
-
-
Al-Abed, Y.1
Dabideen, D.2
Aljabari, B.3
Valster, A.4
Messmer, D.5
Ochani, M.6
Tanovic, M.7
Ochani, K.8
Bacher, M.9
Nicoletti, F.10
Metz, C.11
Pavlov, V.A.12
Miller, E.J.13
Tracey, K.J.14
-
58
-
-
0008290616
-
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis
-
Leppa, S., and Bohmann, D. (1999) Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene 18, 6158-6162
-
(1999)
Oncogene
, vol.18
, pp. 6158-6162
-
-
Leppa, S.1
Bohmann, D.2
-
59
-
-
67749117934
-
Signal integration by JNK and p38 MAPK pathways in cancer development
-
Wagner, E. F., and Nebreda, A. R. (2009) Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9, 537-549
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 537-549
-
-
Wagner, E.F.1
Nebreda, A.R.2
-
60
-
-
0037109011
-
Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium
-
Koebernick, H., Grode, L., David, J. R., Rohde, W., Rolph, M. S., Mittrucker, H. W., and Kaufmann, S. H. (2002) Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium. Proc. Natl. Acad. Sci. U. S. A. 99, 13681-13686
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 13681-13686
-
-
Koebernick, H.1
Grode, L.2
David, J.R.3
Rohde, W.4
Rolph, M.S.5
Mittrucker, H.W.6
Kaufmann, S.H.7
-
61
-
-
0029143676
-
MIF as a glucocorticoid-induced modulator of cytokine production
-
Calandra, T., Bernhagen, J., Metz, C. N., Spiegel, L. A., Bacher, M., Donnelly, T., Cerami, A., and Bucala, R. (1995) MIF as a glucocorticoid-induced modulator of cytokine production. Nature 377, 68-71
-
(1995)
Nature
, vol.377
, pp. 68-71
-
-
Calandra, T.1
Bernhagen, J.2
Metz, C.N.3
Spiegel, L.A.4
Bacher, M.5
Donnelly, T.6
Cerami, A.7
Bucala, R.8
-
62
-
-
77649131948
-
The role of macrophage migration inhibitory factor in Alzheimer's disease
-
Bacher, M., Deuster, O., Aljabari, B., Egensperger, R., Neff, F., Jessen, F., Popp, J., Noelker, C., Reese, J. P., Al-Abed, Y., and Dodel, R. The role of macrophage migration inhibitory factor in Alzheimer's disease. Mol. Med. 16, 116-121
-
Mol. Med.
, vol.16
, pp. 116-121
-
-
Bacher, M.1
Deuster, O.2
Aljabari, B.3
Egensperger, R.4
Neff, F.5
Jessen, F.6
Popp, J.7
Noelker, C.8
Reese, J.P.9
Al-Abed, Y.10
Dodel, R.11
-
63
-
-
33745190762
-
MIF: A new cytokine link between rheumatoid arthritis and atherosclerosis
-
Morand, E. F., Leech, M., and Bernhagen, J. (2006) MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis. Nat. Rev. Drug Discov. 5, 399-410
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 399-410
-
-
Morand, E.F.1
Leech, M.2
Bernhagen, J.3
-
64
-
-
34249066942
-
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
-
Bernhagen, J., Krohn, R., Lue, H., Gregory, J. L., Zernecke, A., Koenen, R. R., Dewor, M., Georgiev, I., Schober, A., Leng, L., Kooistra, T., Fingerle-Rowson, G., Ghezzi, P., Kleemann, R., McColl, S. R., Bucala, R., Hickey, M. J., and Weber, C. (2007) MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat. Med. 13, 587-596
-
(2007)
Nat. Med.
, vol.13
, pp. 587-596
-
-
Bernhagen, J.1
Krohn, R.2
Lue, H.3
Gregory, J.L.4
Zernecke, A.5
Koenen, R.R.6
Dewor, M.7
Georgiev, I.8
Schober, A.9
Leng, L.10
Kooistra, T.11
Fingerle-Rowson, G.12
Ghezzi, P.13
Kleemann, R.14
McColl, S.R.15
Bucala, R.16
Hickey, M.J.17
Weber, C.18
|