-
1
-
-
33746808398
-
Wnt/β-catenin signaling in development and disease
-
Clevers, H. (2006) Wnt/β-catenin signaling in development and disease. Cell 127, 469-480
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
2
-
-
0344687341
-
CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene
-
Bai, Y. Q., Miyake, S., Iwai, T., and Yuasa, Y. (2003) CDX2, a homeobox transcription factor, upregulates transcription of the p21/WAF1/CIP1 gene. Oncogene 22, 7942-7949
-
(2003)
Oncogene
, vol.22
, pp. 7942-7949
-
-
Bai, Y.Q.1
Miyake, S.2
Iwai, T.3
Yuasa, Y.4
-
3
-
-
0035833319
-
Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2
-
Dang, D. T., Mahatan, C. S., Dang, L. H., Agboola, I. A., and Yang, V. W. (2001) Expression of the gut-enriched Krüppel-like factor (Krüppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2. Oncogene 20, 4884-4890
-
(2001)
Oncogene
, vol.20
, pp. 4884-4890
-
-
Dang, D.T.1
Mahatan, C.S.2
Dang, L.H.3
Agboola, I.A.4
Yang, V.W.5
-
4
-
-
0342503644
-
CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling
-
da Costa, L. T., He, T. C., Yu, J., Sparks, A. B., Morin, P. J., Polyak, K., Laken, S., Vogelstein, B., and Kinzler, K. W. (1999) CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling. Oncogene 18, 5010-5014
-
(1999)
Oncogene
, vol.18
, pp. 5010-5014
-
-
Da Costa, L.T.1
He, T.C.2
Yu, J.3
Sparks, A.B.4
Morin, P.J.5
Polyak, K.6
Laken, S.7
Vogelstein, B.8
Kinzler, K.W.9
-
5
-
-
0030937750
-
Homeosis and intestinal tumours in Cdx2 mutant mice
-
Chawengsaksophak, K., James, R., Hammond, V. E., Köntgen, F., and Beck, F. (1997) Homeosis and intestinal tumours in Cdx2 mutant mice. Nature 386, 84-87
-
(1997)
Nature
, vol.386
, pp. 84-87
-
-
Chawengsaksophak, K.1
James, R.2
Hammond, V.E.3
Köntgen, F.4
Beck, F.5
-
6
-
-
0033594940
-
Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice
-
Beck, F., Chawengsaksophak, K., Waring, P., Playford, R. J., and Furness, J. B. (1999) Reprogramming of intestinal differentiation and intercalary regeneration in Cdx2 mutant mice. Proc. Natl. Acad. Sci. U.S.A. 96, 7318-7323
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 7318-7323
-
-
Beck, F.1
Chawengsaksophak, K.2
Waring, P.3
Playford, R.J.4
Furness, J.B.5
-
7
-
-
64549114508
-
Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2
-
Gao, N., White, P., and Kaestner, K. H. (2009) Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. Dev. Cell 16, 588-599
-
(2009)
Dev. Cell
, vol.16
, pp. 588-599
-
-
Gao, N.1
White, P.2
Kaestner, K.H.3
-
8
-
-
84855464779
-
Cdx2 determines the fate of postnatal intestinal endoderm
-
Stringer, E. J., Duluc, I., Saandi, T., Davidson, I., Bialecka, M., Sato, T., Barker, N., Clevers, H., Pritchard, C. A., Winton, D. J., Wright, N. A., Freund, J. N., Deschamps, J., and Beck, F. (2012) Cdx2 determines the fate of postnatal intestinal endoderm. Development 139, 465-474
-
(2012)
Development
, vol.139
, pp. 465-474
-
-
Stringer, E.J.1
Duluc, I.2
Saandi, T.3
Davidson, I.4
Bialecka, M.5
Sato, T.6
Barker, N.7
Clevers, H.8
Pritchard, C.A.9
Winton, D.J.10
Wright, N.A.11
Freund, J.N.12
Deschamps, J.13
Beck, F.14
-
9
-
-
78149485097
-
Dif-ferentiation- specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2
-
Verzi, M. P., Shin, H., He, H. H., Sulahian, R., Meyer, C. A., Montgomery, R. K., Fleet, J. C., Brown, M., Liu, X. S., and Shivdasani, R. A. (2010) Dif-ferentiation- specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Dev. Cell 19, 713-726
-
(2010)
Dev. Cell
, vol.19
, pp. 713-726
-
-
Verzi, M.P.1
Shin, H.2
He, H.H.3
Sulahian, R.4
Meyer, C.A.5
Montgomery, R.K.6
Fleet, J.C.7
Brown, M.8
Liu, X.S.9
Shivdasani, R.A.10
-
10
-
-
0035877760
-
Intestinal epithelial cell differentiation involves activation of p38 mitogenactivated protein kinase that regulates the homeobox transcription factor CDX2
-
Houde, M., Laprise, P., Jean, D., Blais, M., Asselin, C., and Rivard, N. (2001) Intestinal epithelial cell differentiation involves activation of p38 mitogenactivated protein kinase that regulates the homeobox transcription factor CDX2. J. Biol. Chem. 276, 21885-21894
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21885-21894
-
-
Houde, M.1
Laprise, P.2
Jean, D.3
Blais, M.4
Asselin, C.5
Rivard, N.6
-
11
-
-
0035214124
-
Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity
-
Rings, E. H., Boudreau, F., Taylor, J. K., Moffett, J., Suh, E. R., and Traber, P. G. (2001) Phosphorylation of the serine 60 residue within the Cdx2 activation domain mediates its transactivation capacity. Gastroenterology 121, 1437-1450
-
(2001)
Gastroenterology
, vol.121
, pp. 1437-1450
-
-
Rings, E.H.1
Boudreau, F.2
Taylor, J.K.3
Moffett, J.4
Suh, E.R.5
Traber, P.G.6
-
12
-
-
37849029160
-
The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells
-
Gross, I., Duluc, I., Benameur, T., Calon, A., Martin, E., Brabletz, T., Kedinger, M., Domon-Dell, C., and Freund, J. N. (2008) The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells. Oncogene 27, 107-115
-
(2008)
Oncogene
, vol.27
, pp. 107-115
-
-
Gross, I.1
Duluc, I.2
Benameur, T.3
Calon, A.4
Martin, E.5
Brabletz, T.6
Kedinger, M.7
Domon-Dell, C.8
Freund, J.N.9
-
13
-
-
4944240215
-
Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: An active role for the tumor environment in malignant tumor progression
-
Brabletz, T., Spaderna, S., Kolb, J., Hlubek, F., Faller, G., Bruns, C. J., Jung, A., Nentwich, J., Duluc, I., Domon-Dell, C., Kirchner, T., and Freund, J. N. (2004) Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression. Cancer Res. 64, 6973-6977
-
(2004)
Cancer Res.
, vol.64
, pp. 6973-6977
-
-
Brabletz, T.1
Spaderna, S.2
Kolb, J.3
Hlubek, F.4
Faller, G.5
Bruns, C.J.6
Jung, A.7
Nentwich, J.8
Duluc, I.9
Domon-Dell, C.10
Kirchner, T.11
Freund, J.N.12
-
14
-
-
0029156944
-
Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma
-
Ee, H. C., Erler, T., Bhathal, P. S., Young, G. P., and James, R. J. (1995) Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma. Am. J. Pathol. 147, 586-592
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 586-592
-
-
Ee, H.C.1
Erler, T.2
Bhathal, P.S.3
Young, G.P.4
James, R.J.5
-
15
-
-
33846920172
-
Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability
-
Subtil, C., Guérin, E., Schneider, A., Chenard, M. P., Martin, E., Domon-Dell, C., Duluc, I., Brabletz, T., Kedinger, M., Duclos, B., Gaub, M. P., and Freund, J. N. (2007) Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability. Cancer Lett. 247, 197-203
-
(2007)
Cancer Lett.
, vol.247
, pp. 197-203
-
-
Subtil, C.1
Guérin, E.2
Schneider, A.3
Chenard, M.P.4
Martin, E.5
Domon-Dell, C.6
Duluc, I.7
Brabletz, T.8
Kedinger, M.9
Duclos, B.10
Gaub, M.P.11
Freund, J.N.12
-
16
-
-
68049113677
-
Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer
-
Baba, Y., Nosho, K., Shima, K., Freed, E., Irahara, N., Philips, J., Meyerhardt, J. A., Hornick, J. L., Shivdasani, R. A., Fuchs, C. S., and Ogino, S. (2009) Relationship of CDX2 loss with molecular features and prognosis in colorectal cancer. Clin. Cancer Res. 15, 4665-4673
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 4665-4673
-
-
Baba, Y.1
Nosho, K.2
Shima, K.3
Freed, E.4
Irahara, N.5
Philips, J.6
Meyerhardt, J.A.7
Hornick, J.L.8
Shivdasani, R.A.9
Fuchs, C.S.10
Ogino, S.11
-
17
-
-
84877600884
-
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
-
De Sousa E Melo, F., Wang, X., Jansen, M., Fessler, E., Trinh, A., de Rooij, L. P., de Jong, J. H., de Boer, O. J., van Leersum, R., Bijlsma, M. F., Rodermond, H., van der Heijden, M., van Noesel, C. J., Tuynman, J. B., Dekker, E., Markowetz, F., Medema, J. P., and Vermeulen, L. (2013) Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions. Nat. Med. 19, 614-618
-
(2013)
Nat. Med.
, vol.19
, pp. 614-618
-
-
De Sousa, E.1
Melo, F.2
Wang, X.3
Jansen, M.4
Fessler, E.5
Trinh, A.6
De Rooij, L.P.7
De Jong, J.H.8
De Boer, O.J.9
Van Leersum, R.10
Bijlsma, M.F.11
Rodermond, H.12
Van Der Heijden, M.13
Van Noesel, C.J.14
Tuynman, J.B.15
Dekker, E.16
Markowetz, F.17
Medema, J.P.18
Vermeulen, L.19
-
19
-
-
0141869045
-
The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development
-
Bonhomme, C., Duluc, I., Martin, E., Chawengsaksophak, K., Chenard, M. P., Kedinger, M., Beck, F., Freund, J. N., and Domon-Dell, C. (2003) The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development. Gut 52, 1465-1471
-
(2003)
Gut
, vol.52
, pp. 1465-1471
-
-
Bonhomme, C.1
Duluc, I.2
Martin, E.3
Chawengsaksophak, K.4
Chenard, M.P.5
Kedinger, M.6
Beck, F.7
Freund, J.N.8
Domon-Dell, C.9
-
20
-
-
0032577692
-
Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells
-
Mallo, G. V., Soubeyran, P., Lissitzky, J. C., André, F., Farnarier, C., Marvaldi, J., Dagorn, J. C., and Iovanna, J. L. (1998) Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells. J. Biol. Chem. 273, 14030-14036
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14030-14036
-
-
Mallo, G.V.1
Soubeyran, P.2
Lissitzky, J.C.3
André, F.4
Farnarier, C.5
Marvaldi, J.6
Dagorn, J.C.7
Iovanna, J.L.8
-
21
-
-
0037304716
-
Identification of farnesoid X receptor β as a novel mammalian nuclear receptor sensing lanosterol
-
Otte, K., Kranz, H., Kober, I., Thompson, P., Hoefer, M., Haubold, B., Remmel, B., Voss, H., Kaiser, C., Albers, M., Cheruvallath, Z., Jackson, D., Casari, G., Koegl, M., Pääbo, S., Mous, J., Kremoser, C., and Deuschle, U. (2003) Identification of farnesoid X receptor β as a novel mammalian nuclear receptor sensing lanosterol. Mol. Cell Biol. 23, 864-872
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 864-872
-
-
Otte, K.1
Kranz, H.2
Kober, I.3
Thompson, P.4
Hoefer, M.5
Haubold, B.6
Remmel, B.7
Voss, H.8
Kaiser, C.9
Albers, M.10
Cheruvallath, Z.11
Jackson, D.12
Casari, G.13
Koegl, M.14
Pääbo, S.15
Mous, J.16
Kremoser, C.17
Deuschle, U.18
-
22
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
Makishima, M., Okamoto, A. Y., Repa, J. J., Tu, H., Learned, R. M., Luk, A., Hull, M. V., Lustig, K. D., Mangelsdorf, D. J., and Shan, B. (1999) Identification of a nuclear receptor for bile acids. Science 284, 1362-1365
-
(1999)
Science
, vol.284
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Learned, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
23
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks, D. J., Blanchard, S. G., Bledsoe, R. K., Chandra, G., Consler, T. G., Kliewer, S. A., Stimmel, J. B., Willson, T. M., Zavacki, A. M., Moore, D. D., and Lehmann, J. M. (1999) Bile acids: natural ligands for an orphan nuclear receptor. Science 284, 1365-1368
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
Stimmel, J.B.7
Willson, T.M.8
Zavacki, A.M.9
Moore, D.D.10
Lehmann, J.M.11
-
24
-
-
0033026760
-
Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
-
Wang, H., Chen, J., Hollister, K., Sowers, L. C., and Forman, B. M. (1999) Endogenous bile acids are ligands for the nuclear receptor FXR/BAR. Mol. Cell 3, 543-553
-
(1999)
Mol. Cell
, vol.3
, pp. 543-553
-
-
Wang, H.1
Chen, J.2
Hollister, K.3
Sowers, L.C.4
Forman, B.M.5
-
25
-
-
0037094415
-
Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters
-
Huber, R. M., Murphy, K., Miao, B., Link, J. R., Cunningham, M. R., Rupar, M. J., Gunyuzlu, P. L., Haws, T. F., Kassam, A., Powell, F., Hollis, G. F., Young, P. R., Mukherjee, R., and Burn, T. C. (2002) Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters. Gene 290, 35-43
-
(2002)
Gene
, vol.290
, pp. 35-43
-
-
Huber, R.M.1
Murphy, K.2
Miao, B.3
Link, J.R.4
Cunningham, M.R.5
Rupar, M.J.6
Gunyuzlu, P.L.7
Haws, T.F.8
Kassam, A.9
Powell, F.10
Hollis, G.F.11
Young, P.R.12
Mukherjee, R.13
Burn, T.C.14
-
26
-
-
0037414757
-
Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation
-
Zhang, Y., Kast-Woelbern, H. R., and Edwards, P. A. (2003) Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation. J. Biol. Chem. 278, 104-110
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 104-110
-
-
Zhang, Y.1
Kast-Woelbern, H.R.2
Edwards, P.A.3
-
27
-
-
30844445030
-
FXR regulates organic solute transporters α and β in the adrenal gland, kidney, and intestine
-
Lee, H., Zhang, Y., Lee, F. Y., Nelson, S. F., Gonzalez, F. J., and Edwards, P. A. (2006) FXR regulates organic solute transporters α and β in the adrenal gland, kidney, and intestine. J. Lipid Res. 47, 201-214
-
(2006)
J. Lipid Res.
, vol.47
, pp. 201-214
-
-
Lee, H.1
Zhang, Y.2
Lee, F.Y.3
Nelson, S.F.4
Gonzalez, F.J.5
Edwards, P.A.6
-
28
-
-
34447098081
-
Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice
-
Kim, I., Morimura, K., Shah, Y., Yang, Q., Ward, J. M., and Gonzalez, F. J. (2007) Spontaneous hepatocarcinogenesis in farnesoid X receptor-null mice. Carcinogenesis 28, 940-946
-
(2007)
Carcinogenesis
, vol.28
, pp. 940-946
-
-
Kim, I.1
Morimura, K.2
Shah, Y.3
Yang, Q.4
Ward, J.M.5
Gonzalez, F.J.6
-
29
-
-
57149118460
-
Nuclear bile acid receptor FXR protects against intestinal tumorigenesis
-
Modica, S., Murzilli, S., Salvatore, L., Schmidt, D. R., and Moschetta, A. (2008) Nuclear bile acid receptor FXR protects against intestinal tumorigenesis. Cancer Res. 68, 9589-9594
-
(2008)
Cancer Res.
, vol.68
, pp. 9589-9594
-
-
Modica, S.1
Murzilli, S.2
Salvatore, L.3
Schmidt, D.R.4
Moschetta, A.5
-
30
-
-
33847044019
-
Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor
-
Yang, F., Huang, X., Yi, T., Yen, Y., Moore, D. D., and Huang, W. (2007) Spontaneous development of liver tumors in the absence of the bile acid receptor farnesoid X receptor. Cancer Res. 67, 863-867
-
(2007)
Cancer Res.
, vol.67
, pp. 863-867
-
-
Yang, F.1
Huang, X.2
Yi, T.3
Yen, Y.4
Moore, D.D.5
Huang, W.6
-
31
-
-
80052771111
-
Bile acids and colon cancer: Solving the puzzle with nuclear receptors
-
Degirolamo, C., Modica, S., Palasciano, G., and Moschetta, A. (2011) Bile acids and colon cancer: solving the puzzle with nuclear receptors. Trends Mol. Med. 17, 564-572
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 564-572
-
-
Degirolamo, C.1
Modica, S.2
Palasciano, G.3
Moschetta, A.4
-
32
-
-
75449115416
-
The intestinal nuclear receptor signature with epithelial localization patterns and expression modulation in tumors
-
Modica, S., Gofflot, F., Murzilli, S., D'Orazio, A., Salvatore, L., Pellegrini, F., Nicolucci, A., Tognoni, G., Copetti, M., Valanzano, R., Veschi, S., Mari-ani-Costantini, R., Palasciano, G., Schoonjans, K., Auwerx, J., and Moschetta, A. (2010) The intestinal nuclear receptor signature with epithelial localization patterns and expression modulation in tumors. Gastroenterology 138, 636-648
-
(2010)
Gastroenterology
, vol.138
, pp. 636-648
-
-
Modica, S.1
Gofflot, F.2
Murzilli, S.3
D'Orazio, A.4
Salvatore, L.5
Pellegrini, F.6
Nicolucci, A.7
Tognoni, G.8
Copetti, M.9
Valanzano, R.10
Veschi, S.11
Mari-ani-Costantini, R.12
Palasciano, G.13
Schoonjans, K.14
Auwerx, J.15
Moschetta, A.16
-
33
-
-
59649084903
-
Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development
-
Maran, R. R., Thomas, A., Roth, M., Sheng, Z., Esterly, N., Pinson, D., Gao, X., Zhang, Y., Ganapathy, V., Gonzalez, F. J., and Guo, G. L. (2009) Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development. J. Pharmacol. Exp. Ther. 328, 469-477
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.328
, pp. 469-477
-
-
Maran, R.R.1
Thomas, A.2
Roth, M.3
Sheng, Z.4
Esterly, N.5
Pinson, D.6
Gao, X.7
Zhang, Y.8
Ganapathy, V.9
Gonzalez, F.J.10
Guo, G.L.11
-
34
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., Gerard, R. D., Repa, J. J., Mangelsdorf, D. J., and Kliewer, S. A. (2005) Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab. 2, 217-225
-
(2005)
Cell Metab.
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
Peng, L.4
Cummins, C.L.5
McDonald, J.G.6
Luo, G.7
Jones, S.A.8
Goodwin, B.9
Richardson, J.A.10
Gerard, R.D.11
Repa, J.J.12
Mangelsdorf, D.J.13
Kliewer, S.A.14
-
35
-
-
0033570028
-
Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene: Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer
-
Grober, J., Zaghini, I., Fujii, H., Jones, S. A., Kliewer, S. A., Willson, T. M., Ono, T., and Besnard, P. (1999) Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene: involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer. J. Biol. Chem. 274, 29749-29754
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29749-29754
-
-
Grober, J.1
Zaghini, I.2
Fujii, H.3
Jones, S.A.4
Kliewer, S.A.5
Willson, T.M.6
Ono, T.7
Besnard, P.8
-
36
-
-
33644979579
-
The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-α and -β genes
-
Landrier, J. F., Eloranta, J. J., Vavricka, S. R., and Kullak-Ublick, G. A. (2006) The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-α and -β genes. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G476-G485
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
, pp. G476-G485
-
-
Landrier, J.F.1
Eloranta, J.J.2
Vavricka, S.R.3
Kullak-Ublick, G.A.4
-
37
-
-
63849322336
-
Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio
-
Modica, S., Bellafante, E., and Moschetta, A. (2009) Master regulation of bile acid and xenobiotic metabolism via the FXR, PXR and CAR trio. Front. Biosci. 14, 4719-4745
-
(2009)
Front. Biosci.
, vol.14
, pp. 4719-4745
-
-
Modica, S.1
Bellafante, E.2
Moschetta, A.3
-
38
-
-
0028943821
-
Multiplex PCR analysis and genotype-phenotype correlations of frequent APC mutations
-
Cama, A., Palmirotta, R., Curia, M. C., Esposito, D. L., Ranieri, A., Ficari, F., Valanzano, R., Battista, P., Modesti, A., and Tonelli, F. (1995) Multiplex PCR analysis and genotype-phenotype correlations of frequent APC mutations. Hum. Mutat. 5, 144-152
-
(1995)
Hum. Mutat.
, vol.5
, pp. 144-152
-
-
Cama, A.1
Palmirotta, R.2
Curia, M.C.3
Esposito, D.L.4
Ranieri, A.5
Ficari, F.6
Valanzano, R.7
Battista, P.8
Modesti, A.9
Tonelli, F.10
-
39
-
-
34147107042
-
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
-
Scholl, C., Bansal, D., Döhner, K., Eiwen, K., Huntly, B. J., Lee, B. H., Rücker, F. G., Schlenk, R. F., Bullinger, L., Döhner, H., Gilliland, D. G., and Fröhling, S. (2007) The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis. J. Clin. Invest. 117, 1037-1048
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1037-1048
-
-
Scholl, C.1
Bansal, D.2
Döhner, K.3
Eiwen, K.4
Huntly, B.J.5
Lee, B.H.6
Rücker, F.G.7
Schlenk, R.F.8
Bullinger, L.9
Döhner, H.10
Gilliland, D.G.11
Fröhling, S.12
-
40
-
-
34547446534
-
A real-time PCR method to rapidly titer adenovirus stocks
-
Thomas, M. A., Lichtenstein, D. L., Krajcsi, P., and Wold, W. S. (2007) A real-time PCR method to rapidly titer adenovirus stocks. Methods Mol. Med. 130, 185-192
-
(2007)
Methods Mol. Med.
, vol.130
, pp. 185-192
-
-
Thomas, M.A.1
Lichtenstein, D.L.2
Krajcsi, P.3
Wold, W.S.4
-
41
-
-
84859439016
-
Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and β-catenin activity in colon cancer cells
-
Hinkel, I., Duluc, I., Martin, E., Guenot, D., Freund, J. N., and Gross, I. (2012) Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and β-catenin activity in colon cancer cells. Gastroenterology 142, 875-885.e3
-
(2012)
Gastroenterology
, vol.142
, pp. 875-885.e3
-
-
Hinkel, I.1
Duluc, I.2
Martin, E.3
Guenot, D.4
Freund, J.N.5
Gross, I.6
-
42
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E. R., and Vogelstein, B. (1990) A genetic model for colorectal tumorigenesis. Cell 61, 759-767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
43
-
-
0033769822
-
Cdx1 and cdx2 expression during intestinal development
-
Silberg, D. G., Swain, G. P., Suh, E. R., and Traber, P. G. (2000) Cdx1 and cdx2 expression during intestinal development. Gastroenterology 119, 961-971
-
(2000)
Gastroenterology
, vol.119
, pp. 961-971
-
-
Silberg, D.G.1
Swain, G.P.2
Suh, E.R.3
Traber, P.G.4
-
44
-
-
0031440118
-
Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation
-
Lorentz, O., Duluc, I., Arcangelis, A. D., Simon-Assmann, P., Kedinger, M., and Freund, J. N. (1997) Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation. J. Cell Biol. 139, 1553-1565
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1553-1565
-
-
Lorentz, O.1
Duluc, I.2
Arcangelis, A.D.3
Simon-Assmann, P.4
Kedinger, M.5
Freund, J.N.6
-
45
-
-
0030032310
-
An intestine-specific homeobox gene regulates proliferation and differentiation
-
Suh, E., and Traber, P. G. (1996) An intestine-specific homeobox gene regulates proliferation and differentiation. Mol. Cell Biol. 16, 619-625
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 619-625
-
-
Suh, E.1
Traber, P.G.2
-
46
-
-
0032960673
-
Mitogen-activated protein kinase activation regulates intestinal epithelial differentiation
-
Taupin, D., and Podolsky, D. K. (1999) Mitogen-activated protein kinase activation regulates intestinal epithelial differentiation. Gastroenterology 116, 1072-1080
-
(1999)
Gastroenterology
, vol.116
, pp. 1072-1080
-
-
Taupin, D.1
Podolsky, D.K.2
-
47
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal, C. J., Tohkin, M., Miyata, M., Ward, J. M., Lambert, G., and Gonzalez, F. J. (2000) Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102, 731-744
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
48
-
-
0033637121
-
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
-
Goodwin, B., Jones, S. A., Price, R. R., Watson, M. A., McKee, D. D., Moore, L. B., Galardi, C., Wilson, J. G., Lewis, M. C., Roth, M. E., Maloney, P. R., Willson, T. M., and Kliewer, S. A. (2000) A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol. Cell 6, 517-526
-
(2000)
Mol. Cell
, vol.6
, pp. 517-526
-
-
Goodwin, B.1
Jones, S.A.2
Price, R.R.3
Watson, M.A.4
McKee, D.D.5
Moore, L.B.6
Galardi, C.7
Wilson, J.G.8
Lewis, M.C.9
Roth, M.E.10
Maloney, P.R.11
Willson, T.M.12
Kliewer, S.A.13
-
49
-
-
0037663483
-
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
-
Holt, J. A., Luo, G., Billin, A. N., Bisi, J., McNeill, Y. Y., Kozarsky, K. F., Donahee, M., Wang, D. Y., Mansfield, T. A., Kliewer, S. A., Goodwin, B., and Jones, S. A. (2003) Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis. Genes Dev. 17, 1581-1591
-
(2003)
Genes Dev.
, vol.17
, pp. 1581-1591
-
-
Holt, J.A.1
Luo, G.2
Billin, A.N.3
Bisi, J.4
McNeill, Y.Y.5
Kozarsky, K.F.6
Donahee, M.7
Wang, D.Y.8
Mansfield, T.A.9
Kliewer, S.A.10
Goodwin, B.11
Jones, S.A.12
-
50
-
-
29244432794
-
Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium
-
Kazumori, H., Ishihara, S., Rumi, M. A., Kadowaki, Y., and Kinoshita, Y. (2006) Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium. Gut 55, 16-25
-
(2006)
Gut
, vol.55
, pp. 16-25
-
-
Kazumori, H.1
Ishihara, S.2
Rumi, M.A.3
Kadowaki, Y.4
Kinoshita, Y.5
|