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Volumn 146, Issue 3, 2014, Pages 543-555

Notch2 activation is protective against anticancer effects of zerumbone in human breast cancer cells

Author keywords

Apoptosis; Notch2; Presenilin 1; Zerumbone

Indexed keywords

NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH4 RECEPTOR; PRESENILIN 1; ZERUMBONE; NOTCH2 PROTEIN, HUMAN; SESQUITERPENE;

EID: 84907599051     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-3059-7     Document Type: Article
Times cited : (36)

References (46)
  • 2
    • 34548268026 scopus 로고    scopus 로고
    • Modelling breast cancer: One size does not fit all
    • DOI 10.1038/nrc2193, PII NRC2193
    • Vargo-Gogola T, Rosen JM (2007) Modelling breast cancer: one size does not fit all. Nat Rev Cancer 7(9):659-672 (Pubitemid 47327411)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.9 , pp. 659-672
    • Vargo-Gogola, T.1    Rosen, J.M.2
  • 3
    • 79551600789 scopus 로고    scopus 로고
    • Breast cancer in 2010: Novel targets and therapies for a personalized approach
    • Higgins MJ, Baselga J (2011) Breast cancer in 2010: novel targets and therapies for a personalized approach. Nat Rev Clin Oncol 8(2):65-66
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.2 , pp. 65-66
    • Higgins, M.J.1    Baselga, J.2
  • 5
    • 84872847361 scopus 로고    scopus 로고
    • The genomic landscape of breast cancer as a therapeutic roadmap
    • Ellis MJ, Perou CM (2013) The genomic landscape of breast cancer as a therapeutic roadmap. Cancer Discov 3(1):27-34
    • (2013) Cancer Discov , vol.3 , Issue.1 , pp. 27-34
    • Ellis, M.J.1    Perou, C.M.2
  • 7
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ (2003) Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3(10):768-780
    • (2003) Nat Rev Cancer , vol.3 , Issue.10 , pp. 768-780
    • Surh, Y.J.1
  • 10
    • 84868204647 scopus 로고    scopus 로고
    • Zerumbone causes Bax- and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo
    • Sehrawat A, Arlotti JA, Murakami A, Singh SV (2012) Zerumbone causes Bax- and Bak-mediated apoptosis in human breast cancer cells and inhibits orthotopic xenograft growth in vivo. Breast Cancer Res Treat 136(2):429-441
    • (2012) Breast Cancer Res Treat , vol.136 , Issue.2 , pp. 429-441
    • Sehrawat, A.1    Arlotti, J.A.2    Murakami, A.3    Singh, S.V.4
  • 13
    • 58249091747 scopus 로고    scopus 로고
    • Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice
    • Kim M, Miyamoto S, Yasui Y, Oyama T, Murakami A, Tanaka T (2009) Zerumbone, a tropical ginger sesquiterpene, inhibits colon and lung carcinogenesis in mice. Int J Cancer 124(2):264-271
    • (2009) Int J Cancer , vol.124 , Issue.2 , pp. 264-271
    • Kim, M.1    Miyamoto, S.2    Yasui, Y.3    Oyama, T.4    Murakami, A.5    Tanaka, T.6
  • 14
    • 77954426332 scopus 로고    scopus 로고
    • Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: Involvement of mitochondria-regulated apoptosis
    • Abdelwahab SI, Abdul AB, Devi N, Taha MM, Al-zubairi AS, Mohan S, Mariod AA (2010) Regression of cervical intraepithelial neoplasia by zerumbone in female Balb/c mice prenatally exposed to diethylstilboestrol: involvement of mitochondria-regulated apoptosis. Exp Toxicol Pathol 62(5):461-469
    • (2010) Exp Toxicol Pathol , vol.62 , Issue.5 , pp. 461-469
    • Abdelwahab, S.I.1    Abdul, A.B.2    Devi, N.3    Taha, M.M.4    Al-zubairi, A.S.5    Mohan, S.6    Mariod, A.A.7
  • 15
    • 77954427466 scopus 로고    scopus 로고
    • Potential chemoprevention of diethylni-trosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet)
    • Taha MM, Abdul AB, Abdullah R, Ibrahim TA, Abdelwahab SI, Mohan S (2010) Potential chemoprevention of diethylni-trosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet). Chem Biol Interact 186(3):295-305
    • (2010) Chem Biol Interact , vol.186 , Issue.3 , pp. 295-305
    • Taha, M.M.1    Abdul, A.B.2    Abdullah, R.3    Ibrahim, T.A.4    Abdelwahab, S.I.5    Mohan, S.6
  • 16
    • 0036258778 scopus 로고    scopus 로고
    • Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: The alpha,beta-unsaturated carbonyl group is a prerequisite
    • Murakami A, Takahashi D, Kinoshita T, Koshimizu K, Kim HW, Yoshihiro A, Nakamura Y, Jiwajinda S, Terao J, Ohigashi H (2002) Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the a, b-unsaturated carbonyl group is a prerequisite. Carcinogenesis 23(5):795-802 (Pubitemid 34567518)
    • (2002) Carcinogenesis , vol.23 , Issue.5 , pp. 795-802
    • Murakami, A.1    Takahashi, D.2    Kinoshita, T.3    Koshimizu, K.4    Kim, H.W.5    Yoshihiro, A.6    Nakamura, Y.7    Jiwajinda, S.8    Terao, J.9    Ohigashi, H.10
  • 17
    • 4143081630 scopus 로고    scopus 로고
    • Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes
    • DOI 10.1016/j.febslet.2004.07.042, PII S0014579304009068
    • Nakamura Y, Yoshida C, Murakami A, Ohigashi H, Osawa T, Uchida K (2004) Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes. FEBS Lett 572(1-3):245-250 (Pubitemid 39092543)
    • (2004) FEBS Letters , vol.572 , Issue.1-3 , pp. 245-250
    • Nakamura, Y.1    Yoshida, C.2    Murakami, A.3    Ohigashi, H.4    Osawa, T.5    Uchida, K.6
  • 18
    • 27144512700 scopus 로고    scopus 로고
    • Zerumbone abolishes NF-jB and IjBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion
    • DOI 10.1038/sj.onc.1208845, PII 1208845
    • Takada Y, Murakami A, Aggarwal BB (2005) Zerumbone abolishes NF-jB and IjBa kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion. Oncogene 24(46):6957-6969 (Pubitemid 41509418)
    • (2005) Oncogene , vol.24 , Issue.46 , pp. 6957-6969
    • Takada, Y.1    Murakami, A.2    Aggarwal, B.B.3
  • 19
    • 33751332527 scopus 로고    scopus 로고
    • Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway
    • DOI 10.1111/j.1349-7006.2006.00362.x
    • Xian M, Ito K, Nakazato T, Shimizu T, Chen CK, Yamato K, Murakami A, Ohigashi H, Ikeda Y, Kizaki M (2007) Zerumbone, a bioactive sesquiterpene, induces G2/M cell cycle arrest and apoptosis in leukemia cells via a Fas- and mitochondria-mediated pathway. Cancer Sci 98(1):118-126 (Pubitemid 44803930)
    • (2007) Cancer Science , vol.98 , Issue.1 , pp. 118-126
    • Xian, M.1    Ito, K.2    Nakazato, T.3    Shimizu, T.4    Chen, C.-K.5    Yamato, K.6    Murakami, A.7    Ohigashi, H.8    Ikeda, Y.9    Kizaki, M.10
  • 20
    • 34247218059 scopus 로고    scopus 로고
    • Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/ Bcl-2 ratio
    • Sakinah SA, Handayani ST, Hawariah LP (2007) Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/ Bcl-2 ratio. Cancer Cell Int 3(7):4
    • (2007) Cancer Cell Int , vol.3 , Issue.7 , pp. 4
    • Sakinah, S.A.1    Handayani, S.T.2    Hawariah, L.P.3
  • 21
    • 46649095470 scopus 로고    scopus 로고
    • Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription
    • Hosoya T, Arai MA, Koyano T, Kowithayakorn T, Ishibashi M (2008) Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription. Chembiochem 9(7):1082-1092
    • (2008) Chembiochem , vol.9 , Issue.7 , pp. 1082-1092
    • Hosoya, T.1    Arai, M.A.2    Koyano, T.3    Kowithayakorn, T.4    Ishibashi, M.5
  • 22
    • 55349099143 scopus 로고    scopus 로고
    • Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells
    • Sung B, Jhurani S, Ahn KS, Mastuo Y, Yi T, Guha S, Liu M, Aggarwal BB (2008) Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells. Cancer Res 68(21):8938-8944
    • (2008) Cancer Res , vol.68 , Issue.21 , pp. 8938-8944
    • Sung, B.1    Jhurani, S.2    Ahn, K.S.3    Mastuo, Y.4    Yi, T.5    Guha, S.6    Liu, M.7    Aggarwal, B.B.8
  • 23
    • 63649147784 scopus 로고    scopus 로고
    • Dysregulation of Hedgehog, Wnt and Notch signalling pathways in breast cancer
    • Zardawi SJ, O'Toole SA, Sutherland RL, Musgrove EA (2009) Dysregulation of Hedgehog, Wnt and Notch signalling pathways in breast cancer. Histol Histopathol 24(3):385-398
    • (2009) Histol Histopathol , vol.24 , Issue.3 , pp. 385-398
    • Zardawi, S.J.1    O'Toole, S.A.2    Sutherland, R.L.3    Musgrove, E.A.4
  • 25
    • 84867880152 scopus 로고    scopus 로고
    • Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells
    • Lee J, Sehrawat A, Singh SV (2012) Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells. Breast Cancer Res Treat 136(1):45-56
    • (2012) Breast Cancer Res Treat , vol.136 , Issue.1 , pp. 45-56
    • Lee, J.1    Sehrawat, A.2    Singh, S.V.3
  • 27
    • 33845221445 scopus 로고    scopus 로고
    • Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak
    • DOI 10.1158/1535-7163.MCT-06-0396
    • Xiao D, Vogel V, Singh SV (2006) Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak. Mol Cancer Ther 5(11):2931-2945 (Pubitemid 44849021)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.11 , pp. 2931-2945
    • Xiao, D.1    Vogel, V.2    Singh, S.V.3
  • 28
    • 0037972262 scopus 로고    scopus 로고
    • 2/M arrest and inducing apoptosis
    • DOI 10.1093/carcin/bgg023
    • Xiao D, Srivastava SK, Lew KL, Zeng Y, Hershberger P, Johnson CS, Trump DL, Singh SV (2003) Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis. Carcinogenesis 24(5):891-897 (Pubitemid 36748905)
    • (2003) Carcinogenesis , vol.24 , Issue.5 , pp. 891-897
    • Xiao, D.1    Srivastava, S.K.2    Lew, K.L.3    Zeng, Y.4    Hershberger, P.5    Johnson, C.S.6    Trump, D.L.7    Singh, S.V.8
  • 29
    • 79960075594 scopus 로고    scopus 로고
    • Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells
    • Sehrawat A, Singh SV (2011) Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells. Cancer Prev Res (Phila) 4(7):1107-1117
    • (2011) Cancer Prev Res (Phila) , vol.4 , Issue.7 , pp. 1107-1117
    • Sehrawat, A.1    Singh, S.V.2
  • 30
    • 84899564826 scopus 로고    scopus 로고
    • Role of Notch signalling pathway in cancer and its association with DNA methylation
    • Aithal MG, Rajeswari N (2013) Role of Notch signalling pathway in cancer and its association with DNA methylation. J Genet 92(3):667-675
    • (2013) J Genet , vol.92 , Issue.3 , pp. 667-675
    • Aithal, M.G.1    Rajeswari, N.2
  • 31
    • 78951481235 scopus 로고    scopus 로고
    • Role of Notch and its oncogenic signaling crosstalk in breast cancer
    • Guo S, Liu M, Gonzalez-Perez RR (2011) Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim Biophys Acta 1815(2):197-213
    • (2011) Biochim Biophys Acta , vol.1815 , Issue.2 , pp. 197-213
    • Guo, S.1    Liu, M.2    Gonzalez-Perez, R.R.3
  • 32
    • 84868204922 scopus 로고    scopus 로고
    • Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migration
    • Kim SH, Sehrawat A, Singh SV (2012) Notch2 activation by benzyl isothiocyanate impedes its inhibitory effect on breast cancer cell migration. Breast Cancer Res Treat 134(3):1067-1079
    • (2012) Breast Cancer Res Treat , vol.134 , Issue.3 , pp. 1067-1079
    • Kim, S.H.1    Sehrawat, A.2    Singh, S.V.3
  • 34
    • 33644660241 scopus 로고    scopus 로고
    • Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors
    • DOI 10.2353/ajpath.2006.050416
    • Hu C, Diévart A, Lupien M, Calvo E, Tremblay G, Jolicoeur P (2006) Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors. Am J Pathol 168(3):973-990 (Pubitemid 43327749)
    • (2006) American Journal of Pathology , vol.168 , Issue.3 , pp. 973-990
    • Hu, C.1    Dievart, A.2    Lupien, M.3    Calvo, E.4    Tremblay, G.5    Jolicoeur, P.6
  • 35
    • 36549010842 scopus 로고    scopus 로고
    • Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
    • DOI 10.1084/jem.20071082
    • Leong KG, Niessen K, Kulic I, Raouf A, Eaves C, Pollet I, Karsan A (2007) Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 204(12):2935-2948 (Pubitemid 350179562)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.12 , pp. 2935-2948
    • Leong, K.G.1    Niessen, K.2    Kulic, I.3    Raouf, A.4    Eaves, C.5    Pollet, I.6    Karsan, A.7
  • 36
    • 24944506696 scopus 로고    scopus 로고
    • High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
    • DOI 10.1158/0008-5472.CAN-05-1069
    • Reedijk M, Odorcic S, Chang L, Zhang H, Miller N, McCready DR, Lockwood G, Egan SE (2005) High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res 65(18):8530-8537 (Pubitemid 41330622)
    • (2005) Cancer Research , vol.65 , Issue.18 , pp. 8530-8537
    • Reedijk, M.1    Odorcic, S.2    Chang, L.3    Zhang, H.4    Miller, N.5    McCready, D.R.6    Lockwood, G.7    Sean, E.8
  • 37
    • 80053162689 scopus 로고    scopus 로고
    • Notch1 is involved in migration and invasion of human breast cancer cells
    • Wang J, Fu L, Gu F, Ma Y (2011) Notch1 is involved in migration and invasion of human breast cancer cells. Oncol Rep 26(5):1295-1303
    • (2011) Oncol Rep , vol.26 , Issue.5 , pp. 1295-1303
    • Wang, J.1    Fu, L.2    Gu, F.3    Ma, Y.4
  • 41
    • 14244269366 scopus 로고    scopus 로고
    • The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer
    • Parr C, Watkins G, Jiang WG (2004) The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer. Int J Mol Med 14(5):779-786
    • (2004) Int J Mol Med , vol.14 , Issue.5 , pp. 779-786
    • Parr, C.1    Watkins, G.2    Jiang, W.G.3
  • 42
    • 23944480964 scopus 로고    scopus 로고
    • Identification of eight genes that are potentially involved in tamoxifen sensitivity in breast cancer cells
    • DOI 10.1038/sj.cr.7290312
    • Zarubin T, Jing Q, New L, Han J (2005) Identification of eight genes that are potentially involved in tamoxifen sensitivity in breast cancer cells. Cell Res 15(6):439-446 (Pubitemid 41642872)
    • (2005) Cell Research , vol.15 , Issue.6 , pp. 439-446
    • Zarubin, T.1    Jing, Q.2    New, L.3    Han, J.4
  • 43
    • 80055055833 scopus 로고    scopus 로고
    • Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration
    • Kim SH, Sehrawat A, Sakao K, Hahm ER, Singh SV (2011) Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration. PLoS One 6(10):e26615
    • (2011) PLoS One , vol.6 , Issue.10
    • Kim, S.H.1    Sehrawat, A.2    Sakao, K.3    Hahm, E.R.4    Singh, S.V.5
  • 44
    • 84866116269 scopus 로고    scopus 로고
    • Notch activation is dispensable for D, L-sulforaphane-mediated inhibition of human prostate cancer cell migration
    • Hahm ER, Chandra-Kuntal K, Desai D, Amin S, Singh SV (2012) Notch activation is dispensable for D, L-sulforaphane-mediated inhibition of human prostate cancer cell migration. PLoS One 7(9):e44957
    • (2012) PLoS One , vol.7 , Issue.9
    • Hahm, E.R.1    Chandra-Kuntal, K.2    Desai, D.3    Amin, S.4    Singh, S.V.5


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