메뉴 건너뛰기




Volumn 6, Issue 10, 2011, Pages

Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; JAGGED2; MEMBRANE PROTEIN; NICASTRIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; PHENETHYL ISOTHIOCYANATE; PRESENILIN 1; UNCLASSIFIED DRUG; ISOTHIOCYANIC ACID DERIVATIVE;

EID: 80055055833     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026615     Document Type: Article
Times cited : (25)

References (45)
  • 2
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phytochemicals
    • Surh YJ, (2003) Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3: 768-780.
    • (2003) Nat Rev Cancer , vol.3 , pp. 768-780
    • Surh, Y.J.1
  • 3
    • 0034538640 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis by isothiocyanates
    • Hecht SS, (2000) Inhibition of carcinogenesis by isothiocyanates. Drug Metab Rev 32: 395-411.
    • (2000) Drug Metab Rev , vol.32 , pp. 395-411
    • Hecht, S.S.1
  • 5
    • 49549098608 scopus 로고    scopus 로고
    • Murine prostate cancer inhibition by dietary phytochemicals-curcumin and phenyethylisothiocyanate
    • Barve A, Khor TO, Hao X, Keum YS, Yang CS, et al. (2008) Murine prostate cancer inhibition by dietary phytochemicals-curcumin and phenyethylisothiocyanate. Pharm Res 25: 2181-2189.
    • (2008) Pharm Res , vol.25 , pp. 2181-2189
    • Barve, A.1    Khor, T.O.2    Hao, X.3    Keum, Y.S.4    Yang, C.S.5
  • 6
    • 79953838313 scopus 로고    scopus 로고
    • Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer
    • Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, et al. (2011) Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer. J Natl Cancer Inst 103: 571-584.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 571-584
    • Powolny, A.A.1    Bommareddy, A.2    Hahm, E.R.3    Normolle, D.P.4    Beumer, J.H.5
  • 7
    • 0017328782 scopus 로고
    • Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds
    • Wattenberg LW, (1977) Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds. J Natl Cancer Inst 58: 395-398.
    • (1977) J Natl Cancer Inst , vol.58 , pp. 395-398
    • Wattenberg, L.W.1
  • 8
    • 0025846911 scopus 로고
    • Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus
    • Stoner GD, Morrissey DT, Heur YH, Daniel EM, Galati AJ, et al. (1991) Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus. Cancer Res 51: 2063-2068.
    • (1991) Cancer Res , vol.51 , pp. 2063-2068
    • Stoner, G.D.1    Morrissey, D.T.2    Heur, Y.H.3    Daniel, E.M.4    Galati, A.J.5
  • 9
    • 42949121566 scopus 로고    scopus 로고
    • Chemoprevention of familial adenomatous polyposis in ApcMin/+ mice by phenethyl isothiocyanate (PEITC)
    • Khor TO, Cheung WK, Prawan A, Reddy BS, Kong AN, (2008) Chemoprevention of familial adenomatous polyposis in ApcMin/+ mice by phenethyl isothiocyanate (PEITC). Mol Carcinog 47: 321-325.
    • (2008) Mol Carcinog , vol.47 , pp. 321-325
    • Khor, T.O.1    Cheung, W.K.2    Prawan, A.3    Reddy, B.S.4    Kong, A.N.5
  • 10
    • 33750448018 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential
    • Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, et al. (2006) Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential. Carcinogenesis 27: 2223-2234.
    • (2006) Carcinogenesis , vol.27 , pp. 2223-2234
    • Xiao, D.1    Lew, K.L.2    Zeng, Y.3    Xiao, H.4    Marynowski, S.W.5
  • 11
    • 17644423471 scopus 로고    scopus 로고
    • Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax
    • Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, et al. (2005) Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax. Clin Cancer Res 11: 2670-2679.
    • (2005) Clin Cancer Res , vol.11 , pp. 2670-2679
    • Xiao, D.1    Zeng, Y.2    Choi, S.3    Lew, K.L.4    Nelson, J.B.5
  • 12
    • 4344649449 scopus 로고    scopus 로고
    • Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest
    • Chiao JW, Wu H, Ramaswamy G, Conaway CC, Chung FL, et al. (2004) Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest. Carcinogenesis 25: 1403-1408.
    • (2004) Carcinogenesis , vol.25 , pp. 1403-1408
    • Chiao, J.W.1    Wu, H.2    Ramaswamy, G.3    Conaway, C.C.4    Chung, F.L.5
  • 13
    • 77953174656 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo
    • Xiao D, Singh SV, (2010) Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo. Pharm Res 27: 722-731.
    • (2010) Pharm Res , vol.27 , pp. 722-731
    • Xiao, D.1    Singh, S.V.2
  • 14
    • 25144443075 scopus 로고    scopus 로고
    • Pharmacokinetics of dietary phenethyl isothiocyanate in rats
    • Ji Y, Kuo Y, Morris ME, (2005) Pharmacokinetics of dietary phenethyl isothiocyanate in rats. Pharm Res 22: 1658-1666.
    • (2005) Pharm Res , vol.22 , pp. 1658-1666
    • Ji, Y.1    Kuo, Y.2    Morris, M.E.3
  • 15
    • 77649281731 scopus 로고    scopus 로고
    • Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats
    • Konsue N, Kirkpatrick J, Kuhnert N, King LJ, Ioannides C, (2010) Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats. Mol Nutr Food Res 54: 426-432.
    • (2010) Mol Nutr Food Res , vol.54 , pp. 426-432
    • Konsue, N.1    Kirkpatrick, J.2    Kuhnert, N.3    King, L.J.4    Ioannides, C.5
  • 16
    • 65949086045 scopus 로고    scopus 로고
    • Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells
    • Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, et al. (2009) Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells. Cancer Res 69: 3704-3712.
    • (2009) Cancer Res , vol.69 , pp. 3704-3712
    • Bommareddy, A.1    Hahm, E.R.2    Xiao, D.3    Powolny, A.A.4    Fisher, A.L.5
  • 17
    • 77956218104 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells
    • Xiao D, Powolny AA, Moura MB, Kelley EE, Bommareddy A, et al. (2010) Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biol Chem 285: 26558-26569.
    • (2010) J Biol Chem , vol.285 , pp. 26558-26569
    • Xiao, D.1    Powolny, A.A.2    Moura, M.B.3    Kelley, E.E.4    Bommareddy, A.5
  • 19
    • 22744440329 scopus 로고    scopus 로고
    • Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells
    • Xu C, Shen G, Chen C, Gélinas C, Kong AN, (2005) Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells. Oncogene 24: 4486-4495.
    • (2005) Oncogene , vol.24 , pp. 4486-4495
    • Xu, C.1    Shen, G.2    Chen, C.3    Gélinas, C.4    Kong, A.N.5
  • 20
    • 33947244444 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo
    • Xiao D, Singh SV, (2007) Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo. Cancer Res 67: 2239-2246.
    • (2007) Cancer Res , vol.67 , pp. 2239-2246
    • Xiao, D.1    Singh, S.V.2
  • 21
    • 68149167106 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells
    • Gong A, He M, Krishna Vanaja DK, Yin P, Karnes RJ, et al. (2009) Phenethyl isothiocyanate inhibits STAT3 activation in prostate cancer cells. Mol Nutr Food Res 53: 878-886.
    • (2009) Mol Nutr Food Res , vol.53 , pp. 878-886
    • Gong, A.1    He, M.2    Krishna Vanaja, D.K.3    Yin, P.4    Karnes, R.J.5
  • 22
    • 33749560635 scopus 로고    scopus 로고
    • Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate
    • Wang LG, Liu XM, Chiao JW, (2006) Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate. Carcinogenesis 27: 2124-2132.
    • (2006) Carcinogenesis , vol.27 , pp. 2124-2132
    • Wang, L.G.1    Liu, X.M.2    Chiao, J.W.3
  • 23
    • 47849127390 scopus 로고    scopus 로고
    • The Notch pathway in prostate development and cancer
    • Leong KG, Gao WQ, (2008) The Notch pathway in prostate development and cancer. Differentiation 76: 699-716.
    • (2008) Differentiation , vol.76 , pp. 699-716
    • Leong, K.G.1    Gao, W.Q.2
  • 24
    • 0034671686 scopus 로고    scopus 로고
    • Notch signaling: from the outside in
    • Mumm JS, Kopan R, (2000) Notch signaling: from the outside in. Dev Biol 228: 151-165.
    • (2000) Dev Biol , vol.228 , pp. 151-165
    • Mumm, J.S.1    Kopan, R.2
  • 25
    • 78651312053 scopus 로고    scopus 로고
    • Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanate-mediated changes in expression of antioxidant defense genes
    • Powolny AA, Singh SV, (2010) Differential response of normal (PrEC) and cancerous human prostate cells (PC-3) to phenethyl isothiocyanate-mediated changes in expression of antioxidant defense genes. Pharm Res 27: 2766-2775.
    • (2010) Pharm Res , vol.27 , pp. 2766-2775
    • Powolny, A.A.1    Singh, S.V.2
  • 26
    • 34548833559 scopus 로고    scopus 로고
    • Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth
    • O'Neill CF, Urs S, Cinelli C, Lincoln A, Nadeau RJ, et al. (2007) Notch2 signaling induces apoptosis and inhibits human MDA-MB-231 xenograft growth. Am J Pathol 171: 1023-1036.
    • (2007) Am J Pathol , vol.171 , pp. 1023-1036
    • O'Neill, C.F.1    Urs, S.2    Cinelli, C.3    Lincoln, A.4    Nadeau, R.J.5
  • 27
    • 36549010842 scopus 로고    scopus 로고
    • Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
    • Leong KG, Niessen K, Kulic I, Raouf A, Eaves C, et al. (2007) Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med 204: 2935-2948.
    • (2007) J Exp Med , vol.204 , pp. 2935-2948
    • Leong, K.G.1    Niessen, K.2    Kulic, I.3    Raouf, A.4    Eaves, C.5
  • 28
    • 59449107891 scopus 로고    scopus 로고
    • Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator
    • Bin Hafeez B, Adhami VM, Asim M, Siddiqui IA, Bhat KM, et al. (2009) Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator. Clin Cancer Res 15: 452-459.
    • (2009) Clin Cancer Res , vol.15 , pp. 452-459
    • Bin Hafeez, B.1    Adhami, V.M.2    Asim, M.3    Siddiqui, I.A.4    Bhat, K.M.5
  • 29
    • 33748872289 scopus 로고    scopus 로고
    • Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells
    • Zhang Y, Wang Z, Ahmed F, Banerjee S, Li Y, et al. (2006) Down-regulation of Jagged-1 induces cell growth inhibition and S phase arrest in prostate cancer cells. Int J Cancer 119: 2071-2077.
    • (2006) Int J Cancer , vol.119 , pp. 2071-2077
    • Zhang, Y.1    Wang, Z.2    Ahmed, F.3    Banerjee, S.4    Li, Y.5
  • 30
    • 77749321234 scopus 로고    scopus 로고
    • Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways
    • Wang Z, Li Y, Banerjee S, Kong D, Ahmad A, et al. (2010) Down-regulation of Notch-1 and Jagged-1 inhibits prostate cancer cell growth, migration and invasion, and induces apoptosis via inactivation of Akt, mTOR, and NF-κB signaling pathways. J Cell Biochem 109: 726-736.
    • (2010) J Cell Biochem , vol.109 , pp. 726-736
    • Wang, Z.1    Li, Y.2    Banerjee, S.3    Kong, D.4    Ahmad, A.5
  • 31
    • 0035476048 scopus 로고    scopus 로고
    • Dynamics of notch expression during murine prostate development and tumorigenesis
    • Shou J, Ross S, Koeppen H, de Sauvage FJ, Gao WQ, (2001) Dynamics of notch expression during murine prostate development and tumorigenesis. Cancer Res 61: 7291-7297.
    • (2001) Cancer Res , vol.61 , pp. 7291-7297
    • Shou, J.1    Ross, S.2    Koeppen, H.3    de Sauvage, F.J.4    Gao, W.Q.5
  • 32
    • 4944241544 scopus 로고    scopus 로고
    • JAGGED1 expression is associated with prostate cancer metastasis and recurrence
    • Santagata S, Demichelis F, Riva A, Varambally S, Hofer MD, et al. (2004) JAGGED1 expression is associated with prostate cancer metastasis and recurrence. Cancer Res 64: 6854-6857.
    • (2004) Cancer Res , vol.64 , pp. 6854-6857
    • Santagata, S.1    Demichelis, F.2    Riva, A.3    Varambally, S.4    Hofer, M.D.5
  • 33
    • 34249058671 scopus 로고    scopus 로고
    • Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stress
    • Alimirah F, Panchanathan R, Davis FJ, Chen J, Choubey D, (2007) Restoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stress. Neoplasia 9: 427-434.
    • (2007) Neoplasia , vol.9 , pp. 427-434
    • Alimirah, F.1    Panchanathan, R.2    Davis, F.J.3    Chen, J.4    Choubey, D.5
  • 34
  • 35
    • 84860390108 scopus 로고    scopus 로고
    • NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications
    • Clementz AG, Rogowski A, Pandya K, Miele L, Osipo C, (2011) NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications. Breast Cancer Res 13: R63.
    • (2011) Breast Cancer Res , vol.13
    • Clementz, A.G.1    Rogowski, A.2    Pandya, K.3    Miele, L.4    Osipo, C.5
  • 36
    • 48649093670 scopus 로고    scopus 로고
    • EGFR signaling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer
    • Kolev V, Mandinova A, Guinea-Viniegra J, Hu B, Lefort K, et al. (2008) EGFR signaling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nat Cell Biol 10: 902-911.
    • (2008) Nat Cell Biol , vol.10 , pp. 902-911
    • Kolev, V.1    Mandinova, A.2    Guinea-Viniegra, J.3    Hu, B.4    Lefort, K.5
  • 37
    • 43549095900 scopus 로고    scopus 로고
    • Down-regulation of Notch-dependent transcription by Akt in vitro
    • Song J, Park S, Kim M, Shin I, (2008) Down-regulation of Notch-dependent transcription by Akt in vitro. FEBS Lett 582: 1693-1699.
    • (2008) FEBS Lett , vol.582 , pp. 1693-1699
    • Song, J.1    Park, S.2    Kim, M.3    Shin, I.4
  • 39
    • 4444239988 scopus 로고    scopus 로고
    • Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells
    • Xiao D, Johnson CS, Trump DL, Singh SV, (2004) Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells. Mol Cancer Ther 3: 567-575.
    • (2004) Mol Cancer Ther , vol.3 , pp. 567-575
    • Xiao, D.1    Johnson, C.S.2    Trump, D.L.3    Singh, S.V.4
  • 40
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP, (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 41
    • 33751555932 scopus 로고    scopus 로고
    • Notch signalling and voltage-gated Na+ channel activity in human prostate cancer cells: independent modulation of in vitro motility
    • Scorey N, Fraser SP, Patel P, Pridgeon C, Dallman MJ, et al. (2006) Notch signalling and voltage-gated Na+ channel activity in human prostate cancer cells: independent modulation of in vitro motility. Prostate Cancer Prostatic Dis 9: 399-406.
    • (2006) Prostate Cancer Prostatic Dis , vol.9 , pp. 399-406
    • Scorey, N.1    Fraser, S.P.2    Patel, P.3    Pridgeon, C.4    Dallman, M.J.5
  • 42
    • 3342895063 scopus 로고    scopus 로고
    • Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2
    • Xiao D, Choi S, Johnson DE, Vogel VG, Johnson CS, et al. (2004) Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2. Oncogene 23: 5594-5606.
    • (2004) Oncogene , vol.23 , pp. 5594-5606
    • Xiao, D.1    Choi, S.2    Johnson, D.E.3    Vogel, V.G.4    Johnson, C.S.5
  • 43
    • 34250721692 scopus 로고    scopus 로고
    • Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
    • Kim YA, Xiao D, Xiao H, Powolny AA, Lew KL, et al. (2007) Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak. Mol Cancer Ther 6: 1599-1609.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1599-1609
    • Kim, Y.A.1    Xiao, D.2    Xiao, H.3    Powolny, A.A.4    Lew, K.L.5
  • 44
    • 0037972262 scopus 로고    scopus 로고
    • Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis
    • Xiao D, Srivastava SK, Lew KL, Zeng Y, Hershberger P, et al. (2003) Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis. Carcinogenesis 24: 891-897.
    • (2003) Carcinogenesis , vol.24 , pp. 891-897
    • Xiao, D.1    Srivastava, S.K.2    Lew, K.L.3    Zeng, Y.4    Hershberger, P.5
  • 45
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.