Positive Selection and Multiple Losses of the LINE-1-Derived L1TD1 Gene in Mammals Suggest a Dual Role in Genome Defense and Pluripotency

PLoS Genetics

Volumn 10, Issue 9, 2014, Pages

  McLaughlin, Richard N ^a   Young, Janet M ^a   Yang, Lei ^b,e   Neme, Rafik ^c   Wichman, Holly A ^b   Malik, Harmit S ^a,d  

^a USA   (United States)

^b UNIVERSITY OF IDAHO   (United States)

^c MAX PLANCK INSTITUTE FOR EVOLUTIONARY BIOLOGY   (Germany)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LONG INTERSPERSED ELEMENT 1 PROTEIN; TRANSPOSASE; UNCLASSIFIED DRUG; L1TD1 PROTEIN, HUMAN; PROTEIN; RETROPOSON;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; DOMESTICATION; GENE; GENE FUNCTION; GENE LOSS; GENETIC ASSOCIATION; GENETIC SELECTION; GENOME; GENOME ANALYSIS; HUMAN GENOME; L1TD1 GENE; MAMMAL; MAMMAL CELL; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLACENTAL MAMMALS; PLURIPOTENT STEM CELL; PRIMATE; PROSIMIAN; RETROPOSON; RODENT; SPECIES EXTINCTION; ANIMAL; EVOLUTION; GENETICS; HUMAN; LONG INTERSPERSED REPEAT; PHYLOGENY;

ANIMALS; BIOLOGICAL EVOLUTION; GENOME; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MAMMALS; MICE; PHYLOGENY; PROTEINS; RETROELEMENTS; RODENTIA;

EID: 84907588702     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004531     Document Type: Article

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