The selection performance of an antibody library displayed on filamentous phage coat proteins p9, p3 and truncated p3

BMC Research Notes

Volumn 7, Issue 1, 2014, Pages

  Huovinen, Tuomas ^a   Syrjänpää, Markku ^a   Sanmark, Hanna ^a   Seppä, Titta ^a   Akter, Sultana ^a   Khan, Liton Md Ferdhos ^a   Lamminmäki, Urpo ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

Fab; g3p; g9p; Hyperphage; p3; p9; Phage display; ScFv; VCS M13

Indexed keywords

CAPSID PROTEIN; DIGOXIGENIN; HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; PEPTIDE LIBRARY; STREPTAVIDIN;

ANTIBODY AFFINITY; CELL SURFACE DISPLAY; ENTEROBACTERIA PHAGE M13; GENETIC ENGINEERING; GENETICS; IMMUNOASSAY; IMMUNOLOGY; METABOLISM; PEPTIDE LIBRARY;

ANTIBODY AFFINITY; BACTERIOPHAGE M13; CAPSID PROTEINS; CELL SURFACE DISPLAY TECHNIQUES; DIGOXIGENIN; GENETIC ENGINEERING; IMMUNOASSAY; IMMUNOGLOBULIN FAB FRAGMENTS; PEPTIDE LIBRARY; RECOMBINANT FUSION PROTEINS; STREPTAVIDIN;

EID: 84907574786     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-7-661     Document Type: Article

References (35)

1. Expression of functional antibody Fv and Fab fragments in Escherichia coli. Plückthun A, Skerra A, Methods Enzymol 1989 178 497 515 2689841
2. A compact phage display human scFv library for selection of antibodies to a wide variety of antigens. Pansri P, Jaruseranee N, Rangnoi K, Kristensen P, Yamabhai M, BMC Biotechnol 2009 9 6 10.1186/1472-6750-9-6 19175944
3. Synthetic customized scFv libraries. Robin G, Martineau P, Methods Mol Biol 2012 907 109 122 10.1007/978-1-61779-974-7-6 22907348
4. A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties. Tiller T, Schuster I, Deppe D, Siegers K, Strohner R, Herrmann T, Berenguer M, Poujol D, Stehle J, Stark Y, Heßling M, Daubert D, Felderer K, Kaden S, Kölln J, Enzelberger M, Urlinger S, MAbs 2013 5 3 445 470 10.4161/mabs.24218 23571156
5. Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library. Yu R, Wang S, Yu YZ, Du WS, Yang F, Yu WY, Sun ZW, J Biomol Screen 2009 14 8 991 998 10.1177/1087057109343206 19726786
6. Adapter-directed display: a modular design for shuttling display on phage surfaces. Wang KC, Wang X, Zhong P, Luo PP, J Mol Biol 2010 395 5 1088 1101 10.1016/j.jmb.2009.11.068 19969002
7. Signal sequences directing cotranslational translocation expand the range of proteins amenable to phage display. Steiner D, Forrer P, Stumpp MT, Plückthun A, Nat Biotechnol 2006 24 7 823 831 10.1038/nbt1218 16823375
8. SRP and Sec pathway leader peptides for antibody phage display and antibody fragment production in E. coli. Thie H, Schirrmann T, Paschke M, Dübel S, Hust M, N Biotechnol 2008 25 1 49 54 10.1016/j.nbt.2008.01.001 18504019
9. Parameters affecting the display of antibodies on phage. Kirsch M, Zaman M, Meier D, Dübel S, Hust M, J Immunol Methods 2005 301 1-2 173 185 15992816
10. On the influence of vector design on antibody phage display. Soltes G, Hust M, Ng KK, Bansal A, Field J, Stewart DI, Dübel S, Cha S, Wiersma EJ, J Biotechnol 2007 127 4 626 637 10.1016/j.jbiotec.2006.08.015 16996161
11. Diversity and censoring of landscape phage libraries. Kuzmicheva GA, Jayanna PK, Sorokulova IB, Petrenko VA, Protein Eng Des Sel 2009 22 1 9 18 18988692
12. T7 lytic phage-displayed peptide libraries exhibit less sequence bias than M13 filamentous phage-displayed peptide libraries. Krumpe LR, Atkinson AJ, Smythers GW, Kandel A, Schumacher KM, McMahon JB, Makowski L, Mori T, Proteomics 2006 6 15 4210 4222 10.1002/pmic.200500606 16819727
13. Oligovalent Fab display on M13 phage improved by directed evolution. Huovinen T, Sanmark H, Ylä-Pelto J, Vehniäinen M, Lamminmäki U, Mol Biotechnol 2010 44 3 221 231 10.1007/s12033-009-9231-3 20012710
14. Two ScFv antibody libraries derived from identical VL-VH framework with different binding site designs display distinct binding profiles. Huovinen T, Syrjänpää M, Sanmark H, Brockmann EC, Azhayev A, Wang Q, Vehniäinen M, Lamminmäki U, Protein Eng Des Sel 2013 26 10 683 693 10.1093/protein/gzt037 23966567
15. A helper phage to improve single-chain antibody presentation in phage display. Rondot S, Koch J, Breitling F, Dübel S, Nat Biotechnol 2001 19 1 75 78 10.1038/83567 11135557
16. Phage antibodies: filamentous phage displaying antibody variable domains. McCafferty J, Griffiths A, Winter G, Chiswell D, Nature 1990 348 6301 552 554 10.1038/348552a0 2247164
17. Functional expression and display of an antibody Fab fragment in Escherichia coli: study of vector designs and culture conditions. Corisdeo S, Wang B, Protein Expr Purif 2004 34 2 270 279 10.1016/j.pep.2003.11.020 15003261
18. A carbohydrate binding module as a diversity-carrying scaffold. Cicortas Gunnarsson L, Nordberg Karlsson E, Albrekt AS, Andersson M, Holst O, Ohlin M, Protein Eng Des Sel 2004 17 3 213 221 10.1093/protein/gzh026 15082834
19. Generation and selection of rabbit antibody libraries by phage display. Rader C, Methods Mol Biol 2009 525 101 128 xiv 10.1007/978-1-59745-554-1-5 19252834
20. Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3. Rauchenberger R, Borges E, Thomassen-Wolf E, Rom E, Adar R, Yaniv Y, Malka M, Chumakov I, Kotzer S, Resnitzky D, Knappik A, Reiffert S, Prassler J, Jury K, Waldherr D, Bauer S, Kretzschmar T, Yayon A, Rothe C, J Biol Chem 2003 278 40 38194 38205 10.1074/jbc.M303164200 12842902
21. Improving the display of proteins on filamentous phage. Jestin J, Volioti G, Winter G, Res Microbiol 2001 152 2 187 191 10.1016/S0923-2508(01)01191-3 11316373
22. Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. Krebber A, Bornhauser S, Burmester J, Honegger A, Willuda J, Bosshard HR, Plückthun A, J Immunol Methods 1997 201 1 35 55 10.1016/S0022-1759(96)00208-6 9032408
23. Reliable titration of filamentous bacteriophages independent of pIII fusion moiety and genome size by using trypsin to restore wild-type pIII phenotype. Løset G, Kristinsson S, Sandlie I, Biotechniques 2008 44 4 551 552 554 10.2144/000112724 18476820
24. Synthetic single-framework antibody library integrated with rapid affinity maturation by VL shuffling. Brockmann EC, Akter S, Savukoski T, Huovinen T, Lehmusvuori A, Leivo J, Saavalainen O, Azhayev A, Lövgren T, Hellman J, Lamminmäki U, Protein Eng Des Sel 2011 24 9 691 700 10.1093/protein/gzr023 21680620
25. Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays. Chan CE, Chan AH, Lim AP, Hanson BJ, J Immunol Methods 2011 373 1-2 79 88 21856306
26. Multimerization behaviour of single chain Fv variants for the tumour-binding antibody B72.3. Desplancq D, King DJ, Lawson AD, Mountain A, Protein Eng 1994 7 8 1027 1033 10.1093/protein/7.8.1027 7809029
27. A method for the generation of combinatorial antibody libraries using pIX phage display. Gao C, Mao S, Kaufmann G, Wirsching P, Lerner RA, Janda KD, Proc Natl Acad Sci U S A 2002 99 20 12612 12616 10.1073/pnas.192467999 12239343
28. De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins. Shi L, Wheeler JC, Sweet RW, Lu J, Luo J, Tornetta M, Whitaker B, Reddy R, Brittingham R, Borozdina L, Chen Q, Amegadzie B, Knight DM, Almagro JC, Tsui P, J Mol Biol 2010 397 2 385 396 10.1016/j.jmb.2010.01.034 20114051
29. Antibody Fab display and selection through fusion to the pIX coat protein of filamentous phage. Tornetta M, Baker S, Whitaker B, Lu J, Chen Q, Pisors E, Shi L, Luo J, Sweet R, Tsui P, J Immunol Methods 2010 360 1-2 39 46 20600082
30. Expanding the versatility of phage display II: improved affinity selection of folded domains on protein VII and IX of the filamentous phage. Løset G, Roos N, Bogen B, Sandlie I, PLoS One 2011 6 2 17433 10.1371/journal.pone.0017433 21390283
31. Selection of human antibody fragments by phage display. Lee CM, Iorno N, Sierro F, Christ D, Nat Protoc 2007 2 11 3001 3008 10.1038/nprot.2007.448 18007636
32. Construction, evaluation and refinement of a large human antibody phage library based on the IgD and IgM variable gene repertoire. Løset G, Løbersli I, Kavlie A, Stacy JE, Borgen T, Kausmally L, Hvattum E, Simonsen B, Hovda MB, Brekke OH, J Immunol Methods 2005 299 1-2 47 62 15914190
33. Phage display. Smith GP, Petrenko VA, Chem Rev 1997 97 2 391 410 10.1021/cr960065d 11848876
34. Synthetic antibodies designed on natural sequence landscapes. Zhai W, Glanville J, Fuhrmann M, Mei L, Ni I, Sundar PD, Van Blarcom T, Abdiche Y, Lindquist K, Strohner R, Telman D, Cappuccilli G, Finlay WJ, Van den Brulle J, Cox DR, Pons J, Rajpal A, J Mol Biol 2011 412 1 55 71 10.1016/j.jmb.2011.07.018 21787786
35. HuCAL PLATINUM, a synthetic Fab library optimized for sequence diversity and superior performance in mammalian expression systems. Prassler J, Thiel S, Pracht C, Polzer A, Peters S, Bauer M, Nörenberg S, Stark Y, Kölln J, Popp A, Urlinger S, Enzelberger M, J Mol Biol 2011 413 1 261 278 10.1016/j.jmb.2011.08.012 21856311