Antibody Fab display and selection through fusion to the pIX coat protein of filamentous phage

Journal of Immunological Methods

Volumn 360, Issue 1-2, 2010, Pages 39-46

  Tornetta, Mark ^a   Baker, Scott ^b   Whitaker, Brian ^a   Lu, Jin ^a   Chen, Qiang ^b   Pisors, Eileen ^a   Shi, Lei ^a   Luo, Jinquan ^a   Sweet, Raymond ^a   Tsui, Ping ^a,c  

^a CENTOCOR INC   (United States)

^b Centocor R and D Inc   (United States)

^c NONE   (United States)

Author keywords

Antibody engineering; Fab; Phage display; PIX; Respiratory syncytia virus; RSV

Indexed keywords

COAT PROTEIN; HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; PROTEIN PIX; UNCLASSIFIED DRUG; CAPSID PROTEIN; COAT PROTEIN, BACTERIOPHAGE M13; EPITOPE; PEPTIDE LIBRARY; PROTEIN BINDING; TUMOR NECROSIS FACTOR ALPHA; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANTIBODY ENGINEERING; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; PHAGE DISPLAY; PHAGEMID; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; ANTIBODY AFFINITY; BACTERIUM TRANSFORMATION; ENTEROBACTERIA PHAGE M13; ESCHERICHIA COLI; GENETICS; HUMAN; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PEPTIDE LIBRARY; PROTEIN ENGINEERING; PROTEIN TERTIARY STRUCTURE; VIROLOGY;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; BACTERIOPHAGE M13; CAPSID PROTEINS; EPITOPES; ESCHERICHIA COLI; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RESPIRATORY SYNCYTIAL VIRUSES; TRANSFORMATION, BACTERIAL; TUMOR NECROSIS FACTOR-ALPHA; VIRAL PROTEINS;

RICE STRIPE VIRUS;

EID: 77955660812     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2010.06.001     Document Type: Article

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