GABA promotes human β-cell proliferation and modulates glucose homeostasis

Diabetes

Volumn 63, Issue 12, 2014, Pages 4197-4205

  Purwana, Indri ^a,b   Zheng, Juan ^a,b,h   Li, Xiaoming ^a,b   Deurloo, Marielle ^b   Son, Dong Ok ^a,b   Zhang, Zhaoyun ^c   Liang, Christie ^a,b   Shen, Eddie ^a,b   Tadkase, Akshaya ^a   Feng, Zhong Ping ^b   Li, Yiming ^c   Hasilo, Craig ^d   Paraskevas, Steven ^d   Bortell, Rita ^e   Greiner, Dale L ^e   Atkinson, Mark ^f   Prud'homme, Gerald J ^g   Wang, Qinghua ^a,b,c  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c FUDAN UNIVERSITY   (China)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF FLORIDA HEALTH   (United States)

^g ST MICHAEL'S HOSPITAL   (Canada)

^h HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCAGON; GLUCOSE; HUMAN INSULIN; INSULIN RECEPTOR SUBSTRATE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; GABAERGIC RECEPTOR AFFECTING AGENT; GLUCOSE BLOOD LEVEL; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL PROLIFERATION; CELL SIZE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANIMAL; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; HOMEOSTASIS; METABOLISM; NONOBESE DIABETIC MOUSE; PANCREAS ISLET TRANSPLANTATION; SCID MOUSE; SECRETION (PROCESS);

ANIMALS; APOPTOSIS; BLOOD GLUCOSE; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; GABA AGENTS; GAMMA-AMINOBUTYRIC ACID; GLUCAGON; HOMEOSTASIS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED NOD; MICE, SCID;

EID: 84907539564     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0153     Document Type: Article

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