Large-scaled metabolic profiling of human dermal fibroblasts derived from pseudoxanthoma elasticum patients and healthy controls

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Kuzaj, Patricia ^a   Kuhn, Joachim ^a   Michalek, Ryan D ^b   Karoly, Edward D ^b   Faust, Isabel ^a   Dabisch Ruthe, Mareike ^a   Knabbe, Cornelius ^a   Hendig, Doris ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b METABOLON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CARBOHYDRATE; COENZYME A; GLYCEROPHOSPHOLIPID; GUANINE; LEUCINE DIPEPTIDE; LIPID; NUCLEOTIDE; PANTOTHENIC ACID; PEPTIDE; POLYPEPTIDE; PURINE; UNCLASSIFIED DRUG; VITAMIN; XENOBIOTIC AGENT; ABCC6 PROTEIN, HUMAN; DIPEPTIDE; FATTY ACID; MULTIDRUG RESISTANCE PROTEIN; PURINE DERIVATIVE; SMALL INTERFERING RNA;

ARTICLE; CELL FUNCTION; CELL LEVEL; CELL METABOLISM; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENERGY METABOLISM; ENZYME METABOLISM; HUMAN; HUMAN CELL; LIPID ANALYSIS; LIPID COMPOSITION; MAJOR CLINICAL STUDY; MASS SPECTROMETRY; METABOLOMICS; MOLECULAR PATHOLOGY; PSEUDOXANTHOMA ELASTICUM; SKIN FIBROBLAST; BIOSYNTHESIS; CALCINOSIS; CELL LINE; CLASSIFICATION; CYTOLOGY; DERMIS; ELASTIC TISSUE; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; METABOLISM; MUTATION; OXIDATIVE STRESS; PATHOLOGY; RNA INTERFERENCE;

CALCINOSIS; CELL LINE; DERMIS; DIPEPTIDES; ELASTIC TISSUE; EXTRACELLULAR MATRIX; FATTY ACIDS; FIBROBLASTS; GENE EXPRESSION; GLYCEROPHOSPHOLIPIDS; GUANINE; HEK293 CELLS; HUMANS; METABOLOMICS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MUTATION; OXIDATIVE STRESS; PANTOTHENIC ACID; PSEUDOXANTHOMA ELASTICUM; PURINES; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84907486851     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108336     Document Type: Article

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