ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation - Brief report

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 9, 2014, Pages 1985-1989

  Jansen, Robert S ^a   Duijst, Suzanne ^a   Mahakena, Sunny ^a   Sommer, Daniela ^b   Szeri, Flóra ^c   Váradi, András ^c   Plomp, Astrid ^d   Bergen, Arthur A ^d,e   Oude Elferink, Ronald P J ^b   Borst, Piet ^a   Van De Wetering, Koen ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

multidrug resistance associated proteins; nucleotides; pathologic calcification; pyrophosphatases; vascular calcification

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 6; PYROPHOSPHATE;

ANIMAL TISSUE; ARTERY CALCIFICATION; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME RELEASE; HUMAN; HUMAN CELL; IN VIVO STUDY; LIVER; LIVER CELL; LIVER CIRCULATION; LIVER PERFUSION; LIVER SINUSOID; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PSEUDOXANTHOMA ELASTICUM; SYSTEMIC CIRCULATION;

MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; NUCLEOTIDES; PATHOLOGIC CALCIFICATION; PYROPHOSPHATASES; VASCULAR CALCIFICATION;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; AGED; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; DIPHOSPHATES; FEMALE; HEK293 CELLS; HELA CELLS; HEPATOCYTES; HOMEOSTASIS; HUMANS; LIVER; MALE; MICE; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PSEUDOXANTHOMA ELASTICUM; RATS;

EID: 84906939754     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.304017     Document Type: Article

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