Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level in endothelial cell nuclei

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Go, Young Mi ^a   Son, Dong Ju ^b   Park, Heonyong ^c   Orr, Michael ^a   Hao, Li ^a   Takabe, Wakako ^b   Kumar, Sandeep ^b   Kang, Dong Won ^b   Kim, Chan Woo ^b   Jo, Hanjoong ^b,d   Jones, Dean P ^a  

^a Division of Pulmonary   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Dankook University   (South Korea)

^d Emory University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPID; THIOL; THIOREDOXIN 1; ANTIOXIDANT; RELA PROTEIN, MOUSE; THIOREDOXIN; TRANSCRIPTION FACTOR RELA; TXN1 PROTEIN, MOUSE; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKENING; ARTERY BLOOD FLOW; ARTICLE; ATHEROGENESIS; CAROTID ARTERY; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DISEASE COURSE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY DISEASE; LIPID BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEOMICS; SHEAR STRESS; SIGNAL TRANSDUCTION; WEIGHT GAIN; AGONISTS; ANIMAL; ATHEROSCLEROSIS; BIOSYNTHESIS; BLOOD FLOW VELOCITY; CARDIOVASCULAR DISEASE; CELL LINE; CYTOLOGY; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGICAL STRESS; TRANSGENIC MOUSE; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTIOXIDANTS; ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; CARDIOVASCULAR DISEASES; CAROTID ARTERIES; CELL ADHESION MOLECULES; CELL LINE; CELL NUCLEUS; CYTOKINES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; MALE; MICE; MICE, TRANSGENIC; OXIDATION-REDUCTION; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; THIOREDOXINS; TRANSCRIPTION FACTOR RELA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84907485959     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108346     Document Type: Article

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