Nitric oxide induces thioredoxin-1 nuclear translocation: Possible association with the p21Ras survival pathway

Biochemical and Biophysical Research Communications

Volumn 348, Issue 4, 2006, Pages 1254-1260

  Arai, Roberto J ^a   Masutani, H ^b   Yodoi, J ^b   Debbas, V ^c   Laurindo, Francisco R ^c   Stern, A ^d   Monteiro, Hugo P ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Nitric oxide; Nitrosothiols; p21Ras; Redox signaling; Thioredoxin

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; PROTEIN INHIBITOR; PROTEIN P21; RAS PROTEIN; THIOREDOXIN; THIOREDOXIN 1; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; CONCENTRATION RESPONSE; DOWN REGULATION; ENZYME INACTIVATION; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL NUCLEUS; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HELA CELLS; HUMANS; NITRIC OXIDE; NITRIC OXIDE DONORS; PROTO-ONCOGENE PROTEINS P21(RAS); S-NITROSO-N-ACETYLPENICILLAMINE; SIGNAL TRANSDUCTION; THIOREDOXIN;

EID: 33747872812     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.178     Document Type: Article

References (27)

1. Holmgren A. Thioredoxin. Ann. Rev. Biochem. 54 (1985) 237-271
2. Bertini R., Howard O.M., Dong H.F., Oppenheim J.J., Bizzarri C., Sergi R., Caselli G., Pagliei S., Romines B., Wilshire J.A., Mengozzi M., Nakamura H., Yodoi J., Pekkari K., Gurunath R., Holmgren A., Herzenberg L.A., Herzenberg L.A., and Ghezzi P. Thioredoxin, a redox enzyme released in infection and inflammation, is a unique chemoattractant for neutrophils, monocytes, and T cells. J. Exp. Med. 189 (1999) 1783-1789
3. Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., Kawabata M., Miyazono K., and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17 (1998) 2596-2606
4. Akamatsu Y., Ohno T., Hirota K., Kagoshima H., Yodoi J., and Shigesada K. Redox regulation of the DNA binding activity in transcription factor PEBP2. The roles of two conserved cysteine residues. J. Biol. Chem. 272 (1997) 14497-14500
5. Hirota K., Matsui M., Iwata S., Nishiyama A., Mori K., and Yodoi J. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc. Natl. Acad. Sci. USA 94 (1997) 3633-3638
6. Hirota K., Murata M., Sachi Y., Nakamura H., Takeuchi J., Mori K., and Yodoi J. Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB. J. Biol. Chem. 274 (1999) 27891-27897
7. Ueno M., Masutani H., Arai R.J., Yamauchi A., Hirota K., Sakai T., Inamoto T., Yamaoka Y., Yodoi J., and Nikaido T. Thioredoxin-dependent redox regulation of p53-mediated p21 activation. J. Biol. Chem. 274 (1999) 35809-35815
8. Makino Y., Yoshikawa N., Okamoto K., Hirota K., Yodoi J., Makino I., and Tanaka H. Direct association with thioredoxin allows redox regulation of glucocorticoid receptor function. J. Biol. Chem. 274 (1999) 3182-3188
9. Lander H.M., Ogiste J.S., K Teng K., and Novogrodsky A. p21ras as a common signaling target of reactive free radicals and cellular redox stress. J. Biol. Chem. 270 (1995) 21195-21198
10. Lander H.M., Hajjar D.P., Hempstead B.L., Mirza U.A., Chait B.T., Campbell S., and Quilliam L.A. A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interaction. J. Biol. Chem. 272 (1997) 4323-4326
11. Oliveira C.J.R., Schindler F., Ventura A.M., Morais M.S., Arai R.J., Debbas V., Stern A., and Monteiro H.P. Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells. Free Radic. Biol. Med. 35 (2003) 381-396
12. Deora A.A., Hajjar D.P., and Lander H.M. Recruitment and activation of Raf-1 kinase by nitric oxide-activated Ras. Biochemistry 39 (2000) 9901-9908
13. Rooij F., and Bos L. Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras. Oncogene 14 (1997) 623-625
14. Feelisch M., Rassaf T., Mnaimneh S., Singh N., Bryan N.S., Jourd'heuil D., and Kelm M. Concomitant S-, N-, and heme-nitros(yl)ation in biological tissues and fluids: Implications for the fate of NO in vivo. FASEB J. 16 (2002) 1775-1785
15. Hoffmann J., Dimmler S., and Haendeler J. Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction. FEBS Lett. 551 (2003) 153-158
16. Miersch S., and Mutus B. Protein S-nitrosation: biochemistry and characterization of protein thiol-NO interactions as cellular signals. Clin. Biochem. 38 (2005) 777-791
17. Bai J., Nakamura H., Kwon Y.W., Hattori I., Yamaguchi Y., Kim Y.C., Kondo N., Oka S., Ueda S., Masutani H., and Yodoi J. Critical roles of thioredoxin in nerve growth factor-mediated signal transduction and neurite outgrowth in PC12 cells. J. Neurosci. 23 (2003) 503-509
18. Schonhoff C.M., Bulseco D.A., Brancho D.M., Parada L.F., and Ross A.H. The Ras-ERK pathway is required for the induction of neuronal nitric oxide synthase in differentiating PC12 cells. J. Neurochem. 78 (2001) 631-639
19. Williams J.G., Pappu K., and Campbell S.L. Structural and biochemical studies of p21Ras S-nitrosylation and nitric oxide-mediated guanine nucleotide exchange. Proc. Natl. Acad. Sci. USA 100 (2003) 6376-6381
20. Pouyssegur J., Volmat V., and Lenormand P. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Biochem. Pharmacol. 64 (2002) 755-763
21. Haendeler J., Hoffmann J., Tischler V., Berk B.C., M Zeiher A., and Dimmeler S. Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat. Cell Biol. 10 (2002) 743-749
22. Tao L., Gao E., Bryan N.S., Qu Y., Liu H H.-R., Hu A., Christopher T.A., Lopez B.L., Yodoi J., Koch W., Feelisch M., and Ma X.L. Cardioprotective effects of thioredoxin in myocardial ischemia and reperfusion: Role of S-nitrosation. Proc. Natl. Acad. Sci. USA 101 (2004) 11471-11476
23. Mitchell D.A., and Marletta M.A. Thioredoxin catalyzes the S-nitrosation of the caspase-3 active site cysteine. Nat. Chem. Biol. 3 (2005) 154-158
24. Sumbayev V.V. S-nitrosylation of thioredoxin mediates activation of apoptosis signal-regulating kinase 1. Arch. Biochem. Biophys. 415 (2003) 133-136
25. Marshall H.E., and Stamler J.S. Nitrosative Stress-induced Apoptosis through Inhibition of NF-kB. J. Biol. Chem. 277 (2002) 34223-34228
26. Nikitovic D., Holmgren A., and Spyrou G. Inhibition of AP-1 DNA Binding by Nitric Oxide Involving Conserved Cysteine Residues in Jun and Fos. Biochem. Biophys. Res. Commun. 242 (1998) 109-112
27. Stoyanovsky D.A., Tyurina Y.Y., Tyurin V.A., Anand D., Mandavia D.N., Gius D., Ivanova J., Pitt B., Billiar T.R., and Kagan V.E. Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J. Am. Chem. Soc. 127 (2005) 15815-15823