Ganoderic acid Me induces the apoptosis of competent T cells and increases the proportion of Treg cells through enhancing the expression and activation of indoleamine 2,3-dioxygenase in mouse lewis lung cancer cells

International Immunopharmacology

Volumn 23, Issue 1, 2014, Pages 192-204

  Que, Zujun ^a   Zou, Fangyuan ^a   Zhang, Anle ^a   Zheng, Yuanhong ^a   Bi, Ling ^a   Zhong, Jianjiang ^a,c   Tian, Jianhui ^b   Liu, Jianwen ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b LONGHUA HOSPITAL AFFILIATED TO SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c Shanghai Jiao Tong University   (China)

Author keywords

Co culture; GA Me; IDO1; Mouse lewis lung cancer cells; Treg

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; CD8 ANTIGEN; CELL PROTEIN; GAMMA INTERFERON; GANODERIC ACID ME; INDOLEAMINE 2,3 DIOXYGENASE; INDOXIMOD; INTERLEUKIN 10; JANUS KINASE 1; KYNURENINE; LACTATE DEHYDROGENASE; STAT1 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRITERPENE DERIVATIVE; TRYPTOPHAN; UNCLASSIFIED DRUG; INTERLEUKIN 1; JANUS KINASE; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CLONE; CELL CULTURE; CELL ISOLATION; CHEMOSENSITIVITY; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEWIS LUNG CARCINOMA CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T CELL DEPLETION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TUMOR IMMUNITY; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CARCINOMA, LEWIS LUNG; DRUG EFFECTS; GANODERMA LUCIDUM; GENETICS; IMMUNOLOGY; METABOLISM; PHYTOTHERAPY; PROCEDURES; TUMOR ESCAPE;

ANIMALS; APOPTOSIS; CARCINOMA, LEWIS LUNG; CD8-POSITIVE T-LYMPHOCYTES; CLONE CELLS; COCULTURE TECHNIQUES; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERFERON-GAMMA; INTERLEUKIN-1; JANUS KINASES; MICE; MICE, INBRED C57BL; PHYTOTHERAPY; REISHI; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY; TRITERPENES; TUMOR ESCAPE;

EID: 84907470659     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.08.001     Document Type: Article

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