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Volumn 13, Issue 17, 2014, Pages 2660-2665

A new function and complexity for protein translation initiation factor eIF2B

Author keywords

EIF2B; G protein; GAP; GDF; GDI; GEF; Translation initiation

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; INITIATION FACTOR 5;

EID: 84907457238     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2014.948797     Document Type: Article
Times cited : (39)

References (38)
  • 1
    • 75149196287 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation and principles of its regulation
    • PMID:20094052
    • Jackson RJ, Hellen CU, Pestova TV. The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol 2010; 11:113- 27; PMID:20094052; http://dx.doi.org/10.1038/nrm2838
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 113-127
    • Jackson, R.J.1    Hellen, C.U.2    Pestova, T.V.3
  • 2
    • 84863889691 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation: New insights and challenges
    • Hinnebusch AG, Lorsch JR. The mechanism of eukaryotic translation initiation: new insights and challenges. Cold Spring Harb Perspect Biol 2012; 4: 29-55; http://dx.doi.org/10.1101/cshperspect.a011544
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. 29-55
    • Hinnebusch, A.G.1    Lorsch, J.R.2
  • 3
    • 0029858531 scopus 로고    scopus 로고
    • Ligand interactions with eukaryotic translation initiation factor 2: Role of the g-subunit
    • PMID:8947054
    • Erickson FL, Hannig EM. Ligand interactions with eukaryotic translation initiation factor 2: role of the g-subunit. EMBO J 1996; 15:6311-20: PMID:8947054
    • (1996) EMBO J , vol.15 , pp. 6311-6320
    • Erickson, F.L.1    Hannig, E.M.2
  • 4
    • 26944435515 scopus 로고    scopus 로고
    • Pi release from eIF2, not GTP hydrolysis, is the step controlled by startsite selection during eukaryotic translation initiation
    • PMID:16246727
    • Algire MA, Maag D, Lorsch JR. Pi release from eIF2, not GTP hydrolysis, is the step controlled by startsite selection during eukaryotic translation initiation. Mol Cell 2005; 20:251-62; PMID:16246727; http://dx.doi.org/10.1016/j.molcel.2005.09.008
    • (2005) Mol Cell , vol.20 , pp. 251-262
    • Algire, M.A.1    Maag, D.2    Lorsch, J.R.3
  • 5
    • 33749340583 scopus 로고    scopus 로고
    • An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation
    • PMID:16990799
    • Singh CR, Lee B, Udagawa T, Mohammad-Qureshi SS, Yamamoto Y, Pavitt GD, Asano K. An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation. EMBO J 2006; 25:4537-46; PMID:16990799; http://dx.doi.org/10.1038/sj.emboj.7601339
    • (2006) EMBO J , vol.25 , pp. 4537-4546
    • Singh, C.R.1    Lee, B.2    Udagawa, T.3    Mohammad-Qureshi, S.S.4    Yamamoto, Y.5    Pavitt, G.D.6    Asano, K.7
  • 6
    • 77952734403 scopus 로고    scopus 로고
    • EIF5 has GDI activity necessary for translational control by eIF2 phosphorylation
    • PMID:20485439
    • Jennings MD, Pavitt GD. eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation. Nature 2010; 465:378-81; PMID:20485439; http://dx.doi.org/10.1038/nature09003
    • (2010) Nature , vol.465 , pp. 378-381
    • Jennings, M.D.1    Pavitt, G.D.2
  • 7
    • 28844478867 scopus 로고    scopus 로고
    • EIF2B, a mediator of general and genespecific translational control
    • PMID:16246152
    • Pavitt GD. eIF2B, a mediator of general and genespecific translational control. Biochem Soc Trans 2005; 33:1487-92; PMID:16246152; http://dx.doi. org/10.1042/BST20051487
    • (2005) Biochem Soc Trans , vol.33 , pp. 1487-1492
    • Pavitt, G.D.1
  • 8
    • 84890605702 scopus 로고    scopus 로고
    • EIF2B promotes eIF5 dissociation from eIF2-GDP to facilitate guanine nucleotide exchange for translation initiation
    • JenningsMD, Zhou Y,Mohammad-Qureshi SS, Bennett D, Pavitt GD. eIF2B promotes eIF5 dissociation from eIF2-GDP to facilitate guanine nucleotide exchange for translation initiation. Genes Dev 2013; 27:2696-707; http://dx.doi.org/10.1101/gad.231514.113
    • (2013) Genes Dev , vol.27 , pp. 2696-2707
    • Jennings, M.D.1    Zhou, Y.2    Mohammad-Qureshi, S.S.3    Bennett, D.4    Pavitt, G.D.5
  • 9
    • 0028107932 scopus 로고
    • Master regulators of membrane trafficking
    • Rab Gtpases PMID:7986528
    • Pfeffer SR. Rab GTPases: master regulators of membrane trafficking. Curr Opin Cell Biol 1994; 6:522- 6; PMID:7986528; http://dx.doi.org/10.1016/0955- 0674(94)90071-X
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 522-526
    • Pfeffer, S.R.1
  • 10
    • 0031023505 scopus 로고    scopus 로고
    • Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI
    • PMID:9034329
    • Dirac-Svejstrup AB, Sumizawa T, Pfeffer SR. Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI. EMBO J 1997; 16:465-72; PMID:9034329; http://dx.doi.org/10.1093/emboj/16.3.465
    • (1997) EMBO J , vol.16 , pp. 465-472
    • Dirac-Svejstrup, A.B.1    Sumizawa, T.2    Pfeffer, S.R.3
  • 11
    • 32344451445 scopus 로고    scopus 로고
    • Purification and properties of Yip3/PRA1 as a Rab GDI displacement factor
    • PMID:16473601
    • Sivars U, Aivazian D, Pfeffer S. Purification and properties of Yip3/PRA1 as a Rab GDI displacement factor. Methods Enzymol 2005; 403:348-56; PMID:16473601; http://dx.doi.org/10.1016/S0076- 6879(05)03030-2
    • (2005) Methods Enzymol , vol.403 , pp. 348-356
    • Sivars, U.1    Aivazian, D.2    Pfeffer, S.3
  • 12
    • 84901452168 scopus 로고    scopus 로고
    • EIF2B is a decameric guanine nucleotide exchange factor with a gamma2epsilon2 tetrameric core
    • PMID:24852487
    • Gordiyenko Y, Schmidt C, Jennings MD, Matak- Vinkovic D, Pavitt GD, Robinson CV. eIF2B is a decameric guanine nucleotide exchange factor with a gamma2epsilon2 tetrameric core. Nat Commun 2014; 5:3902; PMID:24852487; http://dx.doi.org/10.1038/ncomms4902
    • (2014) Nat Commun , vol.5 , pp. 3902
    • Gordiyenko, Y.1    Schmidt, C.2    Jennings, M.D.3    Matak- Vinkovic, D.4    Pavitt, G.D.5    Robinson, C.V.6
  • 13
    • 34249699125 scopus 로고    scopus 로고
    • Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo
    • PMID:17512538
    • Singh CR, Udagawa T, Lee B, Wassink S, He H, Yamamoto Y, Anderson JT, Pavitt GD, Asano K. Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo. J Mol Biol 2007; 370:315-30; PMID:17512538; http://dx.doi.org/10.1016/j.jmb.2007.04.034
    • (2007) J Mol Biol , vol.370 , pp. 315-330
    • Singh, C.R.1    Udagawa, T.2    Lee, B.3    Wassink, S.4    He, H.5    Yamamoto, Y.6    Anderson, J.T.7    Pavitt, G.D.8    Asano, K.9
  • 14
    • 0033559265 scopus 로고    scopus 로고
    • Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase- activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2
    • PMID:10075937
    • Asano K, Krishnamoorthy T, Phan L, Pavitt GD, Hinnebusch AG. Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase- activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2. EMBO J 1999; 18:1673-88; PMID:10075937; http://dx.doi.org/10.1093/emboj/18.6.1673
    • (1999) EMBO J , vol.18 , pp. 1673-1688
    • Asano, K.1    Krishnamoorthy, T.2    Phan, L.3    Pavitt, G.D.4    Hinnebusch, A.G.5
  • 15
    • 1542368830 scopus 로고    scopus 로고
    • Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue
    • PMID:14681227
    • Boesen T, Mohammad SS, Pavitt GD, Andersen GR. Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residue. J Biol Chem 2004; 279:10584-92; PMID:14681227; http://dx.doi.org/10.1074/jbc.M311055200
    • (2004) J Biol Chem , vol.279 , pp. 10584-10592
    • Boesen, T.1    Mohammad, S.S.2    Pavitt, G.D.3    Andersen, G.R.4
  • 16
    • 33746713880 scopus 로고    scopus 로고
    • The crystal structure of the carboxy- terminal domain of human translation initiation factor eIF5
    • PMID:16781736
    • Bieniossek C, Schutz P, Bumann M, Limacher A, Uson I, Baumann U. The crystal structure of the carboxy- terminal domain of human translation initiation factor eIF5. J Mol Biol 2006; 360:457-65; PMID:16781736; http://dx.doi.org/10.1016/j.jmb. 2006.05.021
    • (2006) J Mol Biol , vol.360 , pp. 457-465
    • Bieniossek, C.1    Schutz, P.2    Bumann, M.3    Limacher, A.4    Uson, I.5    Baumann, U.6
  • 17
    • 33744957161 scopus 로고    scopus 로고
    • Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon
    • PMID:16522633
    • Alone PV, Dever TE. Direct binding of translation initiation factor eIF2gamma-G domain to its GTPase-activating and GDP-GTP exchange factors eIF5 and eIF2B epsilon. J Biol Chem 2006; 281:12636-44; PMID:16522633; http://dx.doi.org/10.1074/jbc.M511700200
    • (2006) J Biol Chem , vol.281 , pp. 12636-12644
    • Alone, P.V.1    Dever, T.E.2
  • 18
    • 84866782195 scopus 로고    scopus 로고
    • Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism
    • PMID:22585904
    • Baird TD, Wek RC. Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism. Adv Nutr 2012; 3:307-21; PMID:22585904; http://dx.doi.org/10.3945/an.112.002113
    • (2012) Adv Nutr , vol.3 , pp. 307-321
    • Baird, T.D.1    Wek, R.C.2
  • 19
    • 84863900963 scopus 로고    scopus 로고
    • New insights into translational regulation in the endoplasmic reticulum unfolded protein response
    • Pavitt GD, Ron D. New Insights into Translational Regulation in the Endoplasmic Reticulum Unfolded Protein Response. Cold Spring Harb Perspect Biol 2012; 4:163-75
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. 163-175
    • Pavitt, G.D.1    Ron, D.2
  • 20
    • 0034960171 scopus 로고    scopus 로고
    • Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation
    • PMID:11438658
    • Krishnamoorthy T, Pavitt GD, Zhang F, Dever TE, Hinnebusch AG. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation. Mol Cell Biol 2001; 21:5018- 30; PMID:11438658; http://dx.doi.org/10.1128/MCB.21.15.5018-5030.2001
    • (2001) Mol Cell Biol , vol.21 , pp. 5018-5030
    • Krishnamoorthy, T.1    Pavitt, G.D.2    Zhang, F.3    Dever, T.E.4    Hinnebusch, A.G.5
  • 21
    • 70450207226 scopus 로고    scopus 로고
    • Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease
    • PMID:19909266
    • Pavitt GD, Proud CG. Protein synthesis and its control in neuronal cells with a focus on vanishing white matter disease. Biochem Soc Trans 2009; 37:1298- 310; PMID:19909266; http://dx.doi.org/10.1042/BST0371298
    • (2009) Biochem Soc Trans , vol.37 , pp. 1298-1310
    • Pavitt, G.D.1    Proud, C.G.2
  • 22
    • 1842453031 scopus 로고    scopus 로고
    • Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways
    • PMID:15060152
    • Li W, Wang X, Van Der Knaap MS, Proud CG. Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways. Mol Cell Biol 2004; 24:3295-306; PMID:15060152; http://dx.doi.org/10.1128/MCB. 24.8.3295-3306.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 3295-3306
    • Li, W.1    Wang, X.2    Van Der Knaap, M.S.3    Proud, C.G.4
  • 23
    • 1542344340 scopus 로고    scopus 로고
    • Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity
    • PMID:14993275
    • Richardson JP, Mohammad SS, Pavitt GD. Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity. Mol Cell Biol 2004; 24:2352-63; PMID:14993275; http://dx.doi.org/10.1128/MCB.24.6.2352-2363. 2004
    • (2004) Mol Cell Biol , vol.24 , pp. 2352-2363
    • Richardson, J.P.1    Mohammad, S.S.2    Pavitt, G.D.3
  • 25
    • 0034024628 scopus 로고    scopus 로고
    • Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation
    • PMID:10805739
    • Gomez E, Pavitt GD. Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation. Mol Cell Biol 2000; 20:3965-76; PMID:10805739; http://dx.doi.org/10.1128/MCB. 20.11.3965-3976.2000
    • (2000) Mol Cell Biol , vol.20 , pp. 3965-3976
    • Gomez, E.1    Pavitt, G.D.2
  • 28
    • 84872381683 scopus 로고    scopus 로고
    • A yeast purification system for human translation initiation factors eIF2 and eIF2Bepsilon and their use in the diagnosis of CACH/VWM disease
    • PMID:23335982
    • de Almeida RA, Fogli A, Gaillard M, Scheper GC, Boesflug-Tanguy O, Pavitt GD. A yeast purification system for human translation initiation factors eIF2 and eIF2Bepsilon and their use in the diagnosis of CACH/VWM disease. PloS One 2013; 8:e53958; PMID:23335982; http://dx.doi.org/10.1371/journal.pone.0053958
    • PloS One , vol.2013 , Issue.8 , pp. e53958
    • De Almeida, R.A.1    Fogli, A.2    Gaillard, M.3    Scheper, G.C.4    Boesflug-Tanguy, O.5    Pavitt, G.D.6
  • 29
    • 84901044647 scopus 로고    scopus 로고
    • Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation
    • PMID:24532666
    • Wortham NC, Martinez M, Gordiyenko Y, Robinson CV, Proud CG. Analysis of the subunit organization of the eIF2B complex reveals new insights into its structure and regulation. FASEB J 2014; 28:2225- 37; PMID:24532666; http://dx.doi.org/10.1096/fj.13-243329
    • (2014) FASEB J , vol.28 , pp. 2225-2237
    • Wortham, N.C.1    Martinez, M.2    Gordiyenko, Y.3    Robinson, C.V.4    Proud, C.G.5
  • 30
    • 69749110515 scopus 로고    scopus 로고
    • Crystal structure of the alpha subunit of human translation initiation factor 2B
    • PMID:19631657
    • Hiyama TB, Ito T, Imataka H, Yokoyama S. Crystal structure of the alpha subunit of human translation initiation factor 2B. J Mol Biol 2009; 392:937-51; PMID:19631657; http://dx.doi.org/10.1016/j.jmb. 2009.07.054
    • (2009) J Mol Biol , vol.392 , pp. 937-951
    • Hiyama, T.B.1    Ito, T.2    Imataka, H.3    Yokoyama, S.4
  • 32
    • 15444377849 scopus 로고    scopus 로고
    • Crystal structure of potato tuber ADP-glucose pyrophosphorylase
    • PMID:15692569
    • Jin X, Ballicora MA, Preiss J, Geiger JH. Crystal structure of potato tuber ADP-glucose pyrophosphorylase. EMBO J 2005; 24:694-704; PMID:15692569; http://dx.doi.org/10.1038/sj.emboj.7600551
    • (2005) EMBO J , vol.24 , pp. 694-704
    • Jin, X.1    Ballicora, M.A.2    Preiss, J.3    Geiger, J.H.4
  • 33
    • 84858027453 scopus 로고    scopus 로고
    • Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation
    • PMID:22238343
    • Reid PJ, Mohammad-Qureshi SS, Pavitt GD. Identification of intersubunit domain interactions within eukaryotic initiation factor (eIF) 2B, the nucleotide exchange factor for translation initiation. J Biol Chem 2012; 287:8275-85; PMID:22238343; http://dx.doi.org/10.1074/jbc.M111.331645
    • (2012) J Biol Chem , vol.287 , pp. 8275-8285
    • Reid, P.J.1    Mohammad-Qureshi, S.S.2    Pavitt, G.D.3
  • 34
    • 84874433733 scopus 로고    scopus 로고
    • Regulation of small GTPases by GEFs GAPs, and GDIs
    • PMID:23303910
    • Cherfils J, Zeghouf M. Regulation of small GTPases by GEFs, GAPs, and GDIs. Physiol Rev 2013; 93:269-309; PMID:23303910; http://dx.doi.org/10.1152/physrev.00003.2012
    • (2013) Physiol Rev , vol.93 , pp. 269-309
    • Cherfils, J.1    Zeghouf, M.2
  • 35
    • 0035824431 scopus 로고    scopus 로고
    • Catalysis of guanine nucleotide exchange on eIF2 by eIF2B: Can it be both a substituted enzyme and a sequential mechanism?
    • PMID:11726195
    • Manchester KL. Catalysis of guanine nucleotide exchange on eIF2 by eIF2B: can it be both a substituted enzyme and a sequential mechanism? Biochem Biophys Res Commun 2001; 289:643-6; PMID:11726195; http://dx.doi.org/10.1006/bbrc. 2001.6010
    • (2001) Biochem Biophys Res Commun , vol.289 , pp. 643-646
    • Manchester, K.L.1
  • 36
    • 0034714288 scopus 로고    scopus 로고
    • Purification and kinetic analysis of eIF2B from saccharomyces cerevisiae
    • PMID:10852917
    • Nika J, Yang W, Pavitt GD, Hinnebusch AG, Hannig EM. Purification and kinetic analysis of eIF2B from Saccharomyces cerevisiae. J Biol Chem 2000; 275:26011-7; PMID:10852917; http://dx.doi.org/10.1074/jbc.M003718200
    • (2000) J Biol Chem , vol.275 , pp. 26011-26017
    • Nika, J.1    Yang, W.2    Pavitt, G.D.3    Hinnebusch, A.G.4    Hannig, E.M.5
  • 37
    • 0036790688 scopus 로고    scopus 로고
    • Characterization of the minimal catalytic domain within eIF2B: The guanine-nucleotide exchange factor for translation initiation
    • PMID:12356745
    • Gomez E, Mohammad SS, Pavitt GD. Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation. EMBO J 2002; 21:5292-301; PMID:12356745; http://dx.doi.org/10.1093/emboj/cdf515
    • (2002) EMBO J , vol.21 , pp. 5292-5301
    • Gomez, E.1    Mohammad, S.S.2    Pavitt, G.D.3
  • 38
    • 0032519585 scopus 로고    scopus 로고
    • EIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange
    • PMID:9472020
    • Pavitt GD, Ramaiah KV, Kimball SR, Hinnebusch AG. eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Genes Dev 1998; 12:514-26; PMID:9472020; http://dx.doi.org/10.1101/gad.12.4.514.
    • (1998) Genes Dev , vol.12 , pp. 514-526
    • Pavitt, G.D.1    Ramaiah, K.V.2    Kimball, S.R.3    Hinnebusch, A.G.4


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