-
1
-
-
28844478867
-
EIF2B, a mediator of general and genespecific translational control
-
Pavitt, G. D. (2005) eIF2B, a mediator of general and genespecific translational control. Biochem. Soc. Trans. 33, 1487-1492
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 1487-1492
-
-
Pavitt, G.D.1
-
2
-
-
0023878562
-
The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2
-
Rowlands, A. G., Panniers, R., and Henshaw, E. C. (1988) The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2. J. Biol. Chem. 263, 5526-5533
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5526-5533
-
-
Rowlands, A.G.1
Panniers, R.2
Henshaw, E.C.3
-
3
-
-
0035882047
-
Eukaryotic initiation factor 2B: Identification of multiple phosphorylation sites in the epsilon subunit and their roles in vivo
-
Wang, X., Paulin, F. E. M., Campbell, L. E., Gomez, E., O'Brien, K., Morrice, N., and Proud, C. G. (2001) Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the epsilon subunit and their roles in vivo. EMBO J. 20, 4349-4359
-
(2001)
EMBO J.
, vol.20
, pp. 4349-4359
-
-
Wang, X.1
Paulin, F.E.M.2
Campbell, L.E.3
Gomez, E.4
O'Brien, K.5
Morrice, N.6
Proud, C.G.7
-
4
-
-
40749151132
-
A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B
-
Wang, X., and Proud, C. G. (2008) A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B. Mol. Cell. Biol. 28, 1429-1442
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 1429-1442
-
-
Wang, X.1
Proud, C.G.2
-
5
-
-
0032498112
-
Regulation of eukaryotic initiation factor eIF2B: Glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin
-
Welsh, G. I., Miller, C. M., Loughlin, A. J., Price, N. T., and Proud, C. G. (1998) Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin. FEBS Lett. 421, 125-130
-
(1998)
FEBS Lett.
, vol.421
, pp. 125-130
-
-
Welsh, G.I.1
Miller, C.M.2
Loughlin, A.J.3
Price, N.T.4
Proud, C.G.5
-
6
-
-
0036790688
-
Characterization of the minimal catalytic domain within eIF2B: The guanine-nucleotide exchange factor for translation initiation
-
Gomez, E., Mohammad, S. S., and Pavitt, G. D. (2002) Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation. EMBO J. 21, 5292-5301
-
(2002)
EMBO J.
, vol.21
, pp. 5292-5301
-
-
Gomez, E.1
Mohammad, S.S.2
Pavitt, G.D.3
-
7
-
-
0029811357
-
Cloning of cDNA for the gamma-subunit of mammalian translation initiation factor 2B, the guanine nucleotide exchange factor for eukaryotic initiation factor 2
-
Price, N. T., Kimball, S. R., Jefferson, L. S., and Proud, C. G. (1996) Cloning of cDNA for the gamma-subunit of mammalian translation initiation factor 2B, the guanine nucleotide exchange factor for eukaryotic initiation factor 2. Biochem. J. 318, 631-636
-
(1996)
Biochem. J.
, vol.318
, pp. 631-636
-
-
Price, N.T.1
Kimball, S.R.2
Jefferson, L.S.3
Proud, C.G.4
-
8
-
-
0027411601
-
Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae
-
Bushman, J. L., Asuru, A. I., Matts, R. L., and Hinnebusch, A. G. (1993) Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae. Mol. Cell. Biol. 13, 1920-1932
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 1920-1932
-
-
Bushman, J.L.1
Asuru, A.I.2
Matts, R.L.3
Hinnebusch, A.G.4
-
9
-
-
84863229473
-
Identification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complex
-
Wang, X., Wortham, N. C., Liu, R., and Proud, C. G. (2012) Identification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complex. J. Biol. Chem. 287, 8263-8274
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 8263-8274
-
-
Wang, X.1
Wortham, N.C.2
Liu, R.3
Proud, C.G.4
-
10
-
-
0029791965
-
EIF2B, the guanine nucleotide exchange factor for eukaryotic initiation factor-2: Sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast
-
Price, N. T., Mellor, H., Craddock, B. L., Flowers, K. M., Kimball, S. R., Wilmer, T., Jefferson, L. S., and Proud, C. G. (1996) eIF2B, the guanine nucleotide exchange factor for eukaryotic initiation factor-2: sequence conservation between the alpha, beta and delta subunits of eIF2B from mammals and yeast. Biochem. J. 318, 637-643
-
(1996)
Biochem. J.
, vol.318
, pp. 637-643
-
-
Price, N.T.1
Mellor, H.2
Craddock, B.L.3
Flowers, K.M.4
Kimball, S.R.5
Wilmer, T.6
Jefferson, L.S.7
Proud, C.G.8
-
11
-
-
0032519585
-
EIF2 independently binds two distinct eIF2B subcomplexes that catalyse and regulate guanine-nucleotide exchange
-
Pavitt, G. D., Ramaiah, K. V. A., Kimball, S. R., and Hinnebusch, A. G. (1998) eIF2 independently binds two distinct eIF2B subcomplexes that catalyse and regulate guanine-nucleotide exchange. Genes Dev. 12, 514-526
-
(1998)
Genes Dev.
, vol.12
, pp. 514-526
-
-
Pavitt, G.D.1
Ramaiah, K.V.A.2
Kimball, S.R.3
Hinnebusch, A.G.4
-
12
-
-
0032557657
-
Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2α: Role of the α- And δ-subunits of eIF2B
-
Kimball, S. R., Fabian, J. R., Pavitt, G. D., Hinnebusch, A. G., and Jefferson, L. S. (1998) Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2α: role of the α- and δ-subunits of eIF2B. J. Biol. Chem. 273, 12841-12845
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 12841-12845
-
-
Kimball, S.R.1
Fabian, J.R.2
Pavitt, G.D.3
Hinnebusch, A.G.4
Jefferson, L.S.5
-
13
-
-
0035816596
-
Characterisation of the initiation factor eIF2B complex from mammalian cells as a GDP-dissociation stimulator protein
-
Williams, D. D., Price, N. T., Loughlin, A. J., and Proud, C. G. (2001) Characterisation of the initiation factor eIF2B complex from mammalian cells as a GDP-dissociation stimulator protein. J. Biol. Chem. 276, 24697-24703
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24697-24703
-
-
Williams, D.D.1
Price, N.T.2
Loughlin, A.J.3
Proud, C.G.4
-
14
-
-
0029995664
-
The α-subunit of mammalian initiation factor eIF-2B is essential for catalytic activity
-
Craddock, B. L., and Proud, C. G. (1996) The α-subunit of mammalian initiation factor eIF-2B is essential for catalytic activity. Biochem. Biophys. Res. Commun. 220, 843-847
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.220
, pp. 843-847
-
-
Craddock, B.L.1
Proud, C.G.2
-
15
-
-
80051690654
-
Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes
-
Liu, A. R., van der Lei, H. D., Wang, X., Wortham, N. C., Tang, H., Van Berkel, C. G., Mufunde, T. A., Huang, W., Van der Knaap, M. S., Scheper, G. C., and Proud, C. G. (2011) Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes. Hum. Mutat. 32, 1036-1045
-
(2011)
Hum. Mutat.
, vol.32
, pp. 1036-1045
-
-
Liu, A.R.1
Van Der Lei, H.D.2
Wang, X.3
Wortham, N.C.4
Tang, H.5
Van Berkel, C.G.6
Mufunde, T.A.7
Huang, W.8
Van Der Knaap, M.S.9
Scheper, G.C.10
Proud, C.G.11
-
16
-
-
80053971313
-
The alpha subunit of eukaryotic initiation factor (eIF) 2B is requisite for eIF2-mediated translational suppression of vesicular stomatitis virus
-
Elsby, R., Heiber, J. F., Reid, P., Kimball, S. R., Pavitt, G. D., and Barber, G. N. (2011) The alpha subunit of eukaryotic initiation factor (eIF) 2B is requisite for eIF2-mediated translational suppression of vesicular stomatitis virus. J. Virol. 85, 9716-9725
-
(2011)
J. Virol.
, vol.85
, pp. 9716-9725
-
-
Elsby, R.1
Heiber, J.F.2
Reid, P.3
Kimball, S.R.4
Pavitt, G.D.5
Barber, G.N.6
-
17
-
-
18344386777
-
Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter
-
Leegwater, P. A., Vermeulen, G., Konst, A. A., Naidu, S., Mulders, J., Visser, A., Kersbergen, P., Mobach, D., Fonds, D., Van Berkel, C. G., Lemmers, R. J., Frants, R. R., Oudejans, C. B., Schutgens, R. B., Pronk, J. C., and van der Knaap, M. (2001) Subunits of the translation initiation factor eIF2B are mutant in leukoencephalopathy with vanishing white matter. Nat. Genet. 29, 383-388
-
(2001)
Nat. Genet.
, vol.29
, pp. 383-388
-
-
Leegwater, P.A.1
Vermeulen, G.2
Konst, A.A.3
Naidu, S.4
Mulders, J.5
Visser, A.6
Kersbergen, P.7
Mobach, D.8
Fonds, D.9
Van Berkel, C.G.10
Lemmers, R.J.11
Frants, R.R.12
Oudejans, C.B.13
Schutgens, R.B.14
Pronk, J.C.15
Van Der Knaap, M.16
-
18
-
-
0036156978
-
Mutations of each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter
-
Van der Knaap, M., Leegwater, P. A. J., Könst, A. A. M., Visser, A., naidu, S., Oudejans, C. B. M., Schutgens, R. B. J., and Pronk, J. C. (2002) Mutations of each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter. Ann. Neurol. 51, 264-270
-
(2002)
Ann. Neurol.
, vol.51
, pp. 264-270
-
-
Van Der Knaap, M.1
Leegwater, P.A.J.2
Könst, A.A.M.3
Visser, A.4
Naidu, S.5
Oudejans, C.B.M.6
Schutgens, R.B.J.7
Pronk, J.C.8
-
19
-
-
84898692134
-
Vanishing white matter
-
Chap. 235.1, doi: 10.1036/ommbid.274
-
Van der Knaap, M. S., Bugiani, M., Boor, I., Proud, C. G., and Scheper, G. C. (2010) Vanishing white matter. OMMBID Part 28, Chap. 235.1, doi: 10.1036/ommbid.274
-
(2010)
OMMBID
, Issue.PART 28
-
-
Van Der Knaap, M.S.1
Bugiani, M.2
Boor, I.3
Proud, C.G.4
Scheper, G.C.5
-
20
-
-
1842453031
-
Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways
-
Li, W., Wang, X., van der Knaap, M., and Proud, C. G. (2004) Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse ways. Mol. Cell. Biol. 24, 3295-3306
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3295-3306
-
-
Li, W.1
Wang, X.2
Van Der Knaap, M.3
Proud, C.G.4
-
21
-
-
69749110515
-
Crystal structure of the alpha subunit of human translation initiation factor 2B
-
Hiyama, T. B., Ito, T., Imataka, H., and Yokoyama, S. (2009) Crystal structure of the alpha subunit of human translation initiation factor 2B. J. Mol. Biol. 392, 937-951
-
(2009)
J. Mol. Biol.
, vol.392
, pp. 937-951
-
-
Hiyama, T.B.1
Ito, T.2
Imataka, H.3
Yokoyama, S.4
-
22
-
-
0037086063
-
A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies
-
Sobott, F., Hernandez, H., McCammon, M. G., Tito, M. A., and Robinson, C. V. (2002) A tandem mass spectrometer for improved transmission and analysis of large macromolecular assemblies. Anal. Chem. 74, 1402-1407
-
(2002)
Anal. Chem.
, vol.74
, pp. 1402-1407
-
-
Sobott, F.1
Hernandez, H.2
McCammon, M.G.3
Tito, M.A.4
Robinson, C.V.5
-
23
-
-
1542723081
-
Collisional cooling of large ions in electrospray mass spectrometry
-
Chernushevich, I. V., and Thomson, B. A. (2004) Collisional cooling of large ions in electrospray mass spectrometry. Anal. Chem. 76, 1754-1760
-
(2004)
Anal. Chem.
, vol.76
, pp. 1754-1760
-
-
Chernushevich, I.V.1
Thomson, B.A.2
-
24
-
-
34347228701
-
Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry
-
Hernandez, H., and Robinson, C. V. (2007) Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry. Nat. Protoc. 2, 715-726
-
(2007)
Nat. Protoc.
, vol.2
, pp. 715-726
-
-
Hernandez, H.1
Robinson, C.V.2
-
25
-
-
36448991500
-
Clustal W and Clustal X version 2.0
-
Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A., Lopez, R., Thompson, J. D., Gibson, T. J., and Higgins, D. G. (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23, 2947-2948
-
(2007)
Bioinformatics
, vol.23
, pp. 2947-2948
-
-
Larkin, M.A.1
Blackshields, G.2
Brown, N.P.3
Chenna, R.4
McGettigan, P.A.5
McWilliam, H.6
Valentin, F.7
Wallace, I.M.8
Wilm, A.9
Lopez, R.10
Thompson, J.D.11
Gibson, T.J.12
Higgins, D.G.13
-
26
-
-
65449188232
-
Jalview Version 2: A multiple sequence alignment editor and analysis workbench
-
Waterhouse, A. M., Procter, J. B., Martin, D. M., Clamp, M., and Barton, G. J. (2009) Jalview Version 2: a multiple sequence alignment editor and analysis workbench. Bioinformatics 25, 1189-1191
-
(2009)
Bioinformatics
, vol.25
, pp. 1189-1191
-
-
Waterhouse, A.M.1
Procter, J.B.2
Martin, D.M.3
Clamp, M.4
Barton, G.J.5
-
27
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
Schwanhausser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., and Selbach, M. (2011) Global quantification of mammalian gene expression control. Nature 473, 337-342
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanhausser, B.1
Busse, D.2
Li, N.3
Dittmar, G.4
Schuchhardt, J.5
Wolf, J.6
Chen, W.7
Selbach, M.8
-
28
-
-
0023654065
-
Purification and characterization of eukaryotic initiation factor 2 and a guanine nucleotide exchange factor from rat liver
-
Kimball, S. R., Everson, W. V., Myers, L. M., and Jefferson, L. S. (1987) Purification and characterization of eukaryotic initiation factor 2 and a guanine nucleotide exchange factor from rat liver. J. Biol. Chem. 262, 2220-2227
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 2220-2227
-
-
Kimball, S.R.1
Everson, W.V.2
Myers, L.M.3
Jefferson, L.S.4
-
29
-
-
0030924304
-
Subunit assembly and guanine nucleotide exchange factor activity of eukaryotic initiation factor eIF2B subunits expressed in Sf9 cells
-
Fabian, J. R., Kimball, S. R., Heinzinger, N. K., and Jefferson, L. S. (1997) Subunit assembly and guanine nucleotide exchange factor activity of eukaryotic initiation factor eIF2B subunits expressed in Sf9 cells. J. Biol. Chem. 272, 12359-12365
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12359-12365
-
-
Fabian, J.R.1
Kimball, S.R.2
Heinzinger, N.K.3
Jefferson, L.S.4
-
30
-
-
0242522401
-
EIF2B-related disorders: Antenatal onset and involvement of multiple organs
-
Van der Knaap, M., Van Berkel, C. G., Herms, J., Van Coster, R., Baethmann, M., Naidu, S., Boltshauser, E., Willemsen, M. A., Plecko, B., Hoffmann, G. F., Proud, C. G., Scheper, G. C., and Pronk, J. C. (2003) eIF2B-related disorders: antenatal onset and involvement of multiple organs. Am. J. Hum. Genet. 73, 1199-1207
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 1199-1207
-
-
Van Der Knaap, M.1
Van Berkel, C.G.2
Herms, J.3
Van Coster, R.4
Baethmann, M.5
Naidu, S.6
Boltshauser, E.7
Willemsen, M.A.8
Plecko, B.9
Hoffmann, G.F.10
Proud, C.G.11
Scheper, G.C.12
Pronk, J.C.13
-
31
-
-
0027177312
-
A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast
-
Cigan, A. M., Bushman, J. L., Boal, T. R., and Hinnebusch, A. G. (1993) A protein complex of translational regulators of GCN4 mRNA is the guanine nucleotide-exchange factor for translation initiation factor 2 in yeast. Proc. Natl. Acad. Sci. U. S. A. 90, 5350-5354
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 5350-5354
-
-
Cigan, A.M.1
Bushman, J.L.2
Boal, T.R.3
Hinnebusch, A.G.4
-
32
-
-
77957825617
-
The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo
-
Dev, K., Qiu, H., Dong, J., Zhang, F., Barthlme, D., and Hinnebusch, A. G. (2010) The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo. Mol. Cell. Biol. 30, 5218-5233
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5218-5233
-
-
Dev, K.1
Qiu, H.2
Dong, J.3
Zhang, F.4
Barthlme, D.5
Hinnebusch, A.G.6
-
33
-
-
0030876593
-
A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B
-
Klein, U., Ramirez, M. T., Kobilka, B. K., and von Zastrow, M. (1998) A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B. J. Biol. Chem. 272, 19099-19102
-
(1998)
J. Biol. Chem.
, vol.272
, pp. 19099-19102
-
-
Klein, U.1
Ramirez, M.T.2
Kobilka, B.K.3
Von Zastrow, M.4
-
34
-
-
62049085499
-
Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors
-
Cole, M. D., and Cowling, V. H. (2009) Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors. Oncogene 28, 1169-1175
-
(2009)
Oncogene
, vol.28
, pp. 1169-1175
-
-
Cole, M.D.1
Cowling, V.H.2
|