Carbonic anhydrase inhibitory properties of novel benzylsulfamides using molecular modeling and experimental studies

Bioorganic Chemistry

Volumn 56, Issue , 2014, Pages 75-82

  Göksu, Süleyman ^a   Naderi, Ali ^a   Akbaba, Yusuf ^b   Kalin, Pinar ^a   Akincioǧlu, Akin ^c   Gülçin, Ilhami ^a,d   Durdagi, Serdar ^e   Salmas, Ramin Ekhteiari ^f  

^a ATATÜRK UNIVERSITY   (Turkey)

^b ERZURUM TECHNICAL UNIVERSITY   (Turkey)

^c AGRI IBRAHIM CECEN UNIVERSITY   (Turkey)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

^e BAHCESEHIR UNIVERSITY   (Turkey)

^f ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Benzyl amine; Carbonic anhydrase; Enzyme inhibition; Molecular modeling; Sulfamide; Sulfamoyl carbamate

Indexed keywords

BENZYL N (2 METHOXYBENZYL)SULFAMOYLCARBAMATE; BENZYL N (2,4 DIMETHOXYBENZYL)SULFAMOYLCARBAMATE; BENZYL N (3 METHOXYBENZYL)SULFAMOYLCARBAMATE; BENZYL N (3,4,5 TRIMETHOXYBENZYL)SULFAMOYLCARBAMATE; BENZYL N (3,5 DIMETHOXYBENZYL)SULFAMOYLCARBAMATE; BENZYL N (4 METHOXYBENZYL)SULFAMOYLCARBAMATE; BENZYLSULFAMIDE; CARBON; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; N (2 METHOXYBENZYL)SULFAMIDE; N (3 METHOXYBENZYL)SULFAMIDE; N (3,4,5 TRIMETHOXYBENZYL)SULFAMIDE; N (3,5 DIMETHOXYBENZYL)SULFAMIDE; N (4 METHOXYBENZYL)SULFAMIDE; UNCLASSIFIED DRUG; ISOENZYME; SULFONAMIDE;

ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; ENZYME INHIBITION; ERYTHROCYTE; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROGENOLYSIS; IN VITRO STUDY; MOLECULAR MODEL; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; SYNTHESIS;

CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASE INHIBITORS; ERYTHROCYTES; HUMANS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SULFONAMIDES;

EID: 84907357107     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2014.07.009     Document Type: Article

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