Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

Nitric Oxide - Biology and Chemistry

Volumn 41, Issue , 2014, Pages 146-156

  Módis, Katalin ^c   Coletta, Ciro ^a   Asimakopoulou, Antonia ^a,b   Szczesny, Bartosz ^a   Chao, Celia ^a   Papapetropoulos, Andreas ^a,b   Hellmich, Mark R ^a   Szabo, Csaba ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF PATRAS   (Greece)

^c LAKEHEAD UNIVERSITY   (Canada)

Author keywords

Allosteric modulation; Bioenergetics; Colorectal cancer; Mitochondria; Proliferation

Indexed keywords

AMINOOXYACETIC ACID; CYSTATHIONINE BETA SYNTHASE; HYDROGEN SULFIDE; S ADENOSYLMETHIONINE; CYSTEINE; HOMOCYSTEINE; SMALL INTERFERING RNA;

ARTICLE; BIOENERGY; CELL PROLIFERATION; COLORECTAL CANCER CELL LINE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; HCT116 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LONG TERM EXPOSURE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; CELL VIABILITY; COLORECTAL CANCER; HOMOGENATE; CELL LINE; COLORECTAL TUMOR; DOSE RESPONSE; DRUG EFFECTS; ENERGY METABOLISM; GENE SILENCING; GENETICS; METABOLISM; MITOCHONDRION;

CELL LINE; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYSTATHIONINE BETA-SYNTHASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; GENE SILENCING; HCT116 CELLS; HUMANS; HYDROGEN SULFIDE; MITOCHONDRIA; RNA, SMALL INTERFERING; S-ADENOSYLMETHIONINE;

EID: 84907302687     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2014.03.001     Document Type: Article

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