-
1
-
-
0022402059
-
Myocardial reperfusion: A double-edged sword?
-
Braunwald E and Kloner RA: Myocardial reperfusion: a double-edged sword? J Clin Invest 76: 1713-1719, 1985.
-
(1985)
J Clin Invest
, vol.76
, pp. 1713-1719
-
-
Braunwald, E.1
Kloner, R.A.2
-
2
-
-
17044388962
-
Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process
-
Moens AL, Claeys MJ, Timmermans JP and Vrints CJ: Myocardial ischemia/reperfusion-injury, a clinical view on a complex pathophysiological process. Int J Cardiol 100: 179-190, 2005.
-
(2005)
Int J Cardiol
, vol.100
, pp. 179-190
-
-
Moens, A.L.1
Claeys, M.J.2
Timmermans, J.P.3
Vrints, C.J.4
-
3
-
-
0029925181
-
Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
-
Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K and Mitchinson MJ: Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 347: 781-786, 1996.
-
(1996)
Lancet
, vol.347
, pp. 781-786
-
-
Stephens, N.G.1
Parsons, A.2
Schofield, P.M.3
Kelly, F.4
Cheeseman, K.5
Mitchinson, M.J.6
-
4
-
-
0029091964
-
Myocardial protection with calcium-channel blockers during ischaemia and reperfusion by PTCA
-
Chouairi S, Carrie D and Puel J: Myocardial protection with calcium-channel blockers during ischaemia and reperfusion by PTCA. Eur Heart J 16 (suppl H): 3-8, 1995.
-
(1995)
Eur Heart J
, vol.16
, Issue.SUPPL. H
, pp. 3-8
-
-
Chouairi, S.1
Carrie, D.2
Puel, J.3
-
5
-
-
0033101494
-
The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization: Insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in preventing ischemic complications
-
Narins CR, Miller DP, Califf RM and Topol EJ: The relationship between periprocedural myocardial infarction and subsequent target vessel revascularization following percutaneous coronary revascularization: insights from the EPIC trial. Evaluation of IIb/IIIa platelet receptor antagonist 7E3 in preventing ischemic complications. J Am Coll Cardiol 33: 647-653, 1999.
-
(1999)
J Am Coll Cardiol
, vol.33
, pp. 647-653
-
-
Narins, C.R.1
Miller, D.P.2
Califf, R.M.3
Topol, E.J.4
-
6
-
-
0032480309
-
Metabolic derangement in ischemic heart disease and its therapeutic control
-
Ferrari R, Pepi P, Ferrari F, Nesta F, Benigno M and Visioli O: Metabolic derangement in ischemic heart disease and its therapeutic control. Am J Cardiol 82: 2K-13K, 1998.
-
(1998)
Am J Cardiol
, vol.82
-
-
Ferrari, R.1
Pepi, P.2
Ferrari, F.3
Nesta, F.4
Benigno, M.5
Visioli, O.6
-
7
-
-
0023867107
-
Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury
-
Zweier JL: Measurement of superoxide-derived free radicals in the reperfused heart. Evidence for a free radical mechanism of reperfusion injury. J Biol Chem 263: 1353-1357, 1988.
-
(1988)
J Biol Chem
, vol.263
, pp. 1353-1357
-
-
Zweier, J.L.1
-
8
-
-
0031055348
-
Reperfusion injury: A review of the pathophysiology, clinical manifestations and therapeutic options
-
Maxwell SR and Lip GY: Reperfusion injury: a review of the pathophysiology, clinical manifestations and therapeutic options. Int J Cardiol 58: 95-117, 1997.
-
(1997)
Int J Cardiol
, vol.58
, pp. 95-117
-
-
Maxwell, S.R.1
Lip, G.Y.2
-
9
-
-
0036797558
-
A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs
-
Bianchi C, Wakiyama H, Faro R, et al: A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs. Ann Thorac Surg 74: 1201-1207, 2002.
-
(2002)
Ann Thorac Surg
, vol.74
, pp. 1201-1207
-
-
Bianchi, C.1
Wakiyama, H.2
Faro, R.3
-
10
-
-
2342427941
-
Oxidative stress during myocardial ischaemia and heart failure
-
DOI 10.2174/1381612043384718
-
Ferrari R, Guardigli G, Mele D, Percoco GF, Ceconi C and Curello S: Oxidative stress during myocardial ischaemia and heart failure. Curr Pharm Des 10: 1699-1711, 2004. (Pubitemid 38559780)
-
(2004)
Current Pharmaceutical Design
, vol.10
, Issue.14
, pp. 1699-1711
-
-
Ferrari, R.1
Guardigli, G.2
Mele, D.3
Percoco, G.F.4
Ceconi, C.5
Curello, S.6
-
11
-
-
0031281259
-
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase
-
Zingarelli B, Cuzzocrea S, Zsengeller Z, Salzman AL and Szabó C: Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase. Cardiovasc Res 36: 205-215, 1997.
-
(1997)
Cardiovasc Res
, vol.36
, pp. 205-215
-
-
Zingarelli, B.1
Cuzzocrea, S.2
Zsengeller, Z.3
Salzman, A.L.4
Szabó, C.5
-
12
-
-
0032514225
-
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury
-
Zingarelli B, Salzman AL and Szabó C: Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury. Circ Res 83: 85-94, 1998. (Pubitemid 28322102)
-
(1998)
Circulation Research
, vol.83
, Issue.1
, pp. 85-94
-
-
Zingarelli, B.1
Salzman, A.L.2
Szabo, C.3
-
13
-
-
0036159615
-
Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor
-
Faro R, Toyoda Y, McCully JD, et al: Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor. Ann Thorac Surg 73: 575-581, 2002.
-
(2002)
Ann Thorac Surg
, vol.73
, pp. 575-581
-
-
Faro, R.1
Toyoda, Y.2
McCully, J.D.3
-
14
-
-
18944390248
-
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
-
Jagtap P and Szabó C: Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4: 421-440, 2005.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 421-440
-
-
Jagtap, P.1
Szabó, C.2
-
15
-
-
33845539936
-
Activation of poly(ADP-ribose) polymerase by myocardial ischemia and coronary reperfusion in human circulating leukocytes
-
Toth-Zsamboki E, Horvath E, Vargova K, et al: Activation of poly(ADP-ribose) polymerase by myocardial ischemia and coronary reperfusion in human circulating leukocytes. Mol Med 12: 221-228, 2006.
-
(2006)
Mol Med
, vol.12
, pp. 221-228
-
-
Toth-Zsamboki, E.1
Horvath, E.2
Vargova, K.3
-
16
-
-
17144447467
-
Novel phenanthridinone inhibitors of poly (adenosine 5′- diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents
-
Jagtap P, Soriano FG, Virag L, et al: Novel phenanthridinone inhibitors of poly (adenosine 5′-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents. Crit Care Med 30: 1071-1082, 2002.
-
(2002)
Crit Care Med
, vol.30
, pp. 1071-1082
-
-
Jagtap, P.1
Soriano, F.G.2
Virag, L.3
-
17
-
-
0031239152
-
Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts in vitro
-
DOI 10.1006/jmcc.1997.0496
-
Gilad E, Zingarelli B, Salzman AL and Szabó C: Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts in vitro. J Mol Cell Cardiol 29: 2585-2597, 1997. (Pubitemid 27404449)
-
(1997)
Journal of Molecular and Cellular Cardiology
, vol.29
, Issue.9
, pp. 2585-2597
-
-
Gilad, E.1
Zingarelli, B.2
Salzman, A.L.3
Szabo, C.4
-
18
-
-
0032833924
-
Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity
-
Virag L, Scott GS, Antal-Szalmas P, O'Connor M, Ohshima H and Szabó C: Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity. Mol Pharmacol 56: 824-833, 1999.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 824-833
-
-
Virag, L.1
Scott, G.S.2
Antal-Szalmas, P.3
O'Connor, M.4
Ohshima, H.5
Szabó, C.6
-
21
-
-
9144263639
-
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
-
Wang H, Liao H, Ochani M, et al: Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat Med 10: 1216-1221, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 1216-1221
-
-
Wang, H.1
Liao, H.2
Ochani, M.3
-
22
-
-
0018071338
-
Antagonism of isoproterenol-induced cardiac necrosis in mice by adenosine, dipyridamole and prenylamine
-
Kulkarni DS and Saraf AP: Antagonism of isoproterenol-induced cardiac necrosis in mice by adenosine, dipyridamole and prenylamine. Indian Heart J 30: 220-223, 1978.
-
(1978)
Indian Heart J
, vol.30
, pp. 220-223
-
-
Kulkarni, D.S.1
Saraf, A.P.2
-
23
-
-
0023150584
-
Effect of chlorpromazine on myocardial damage in the calcium paradox
-
Rabkin SW: Effect of chlorpromazine on myocardial damage in the calcium paradox. J Cardiovasc Pharmacol 9: 486-492, 1987.
-
(1987)
J Cardiovasc Pharmacol
, vol.9
, pp. 486-492
-
-
Rabkin, S.W.1
-
24
-
-
33846211540
-
Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death
-
McLean KM, Duffy JY, Pandalai PK, et al: Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death. J Heart Lung Transplant 26: 78-84, 2007.
-
(2007)
J Heart Lung Transplant
, vol.26
, pp. 78-84
-
-
McLean, K.M.1
Duffy, J.Y.2
Pandalai, P.K.3
-
25
-
-
2542490375
-
Glucocorticoid treatment prevents progressive myocardial dysfunction resulting from experimental coronary microembolization
-
Skyschally A, Haude M, Dorge H, et al: Glucocorticoid treatment prevents progressive myocardial dysfunction resulting from experimental coronary microembolization. Circulation 109: 2337-2342, 2004.
-
(2004)
Circulation
, vol.109
, pp. 2337-2342
-
-
Skyschally, A.1
Haude, M.2
Dorge, H.3
-
26
-
-
85047678786
-
1 selective agonist, 2-chloro-N6-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits
-
Tsuchida A, Liu GS, Wilborn WH and Downey JM: Pretreatment with the adenosine A1 selective agonist, 2-chloro-N6-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits. Cardiovasc Res 27: 652-656, 1993. (Pubitemid 23144591)
-
(1993)
Cardiovascular Research
, vol.27
, Issue.4
, pp. 652-656
-
-
Tsuchida, A.1
Liu, G.S.2
Wilborn, W.H.3
Downey, J.M.4
-
27
-
-
0030293660
-
A1 adenosine receptor antagonists block ischemia-reperfusion injury of the heart
-
Neely CF, DiPierro FV, Kong M, Greelish JP and Gardner TJ: A1 adenosine receptor antagonists block ischemia-reperfusion injury of the heart. Circulation 94: II376-II380, 1996.
-
(1996)
Circulation
, vol.94
-
-
Neely, C.F.1
DiPierro, F.V.2
Kong, M.3
Greelish, J.P.4
Gardner, T.J.5
-
28
-
-
0036084754
-
Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction
-
Yang Z, Cerniway RJ, Byford AM, Berr SS, French BA and Matherne GP: Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction. Am J Physiol Heart Circ Physiol 282: H949-H955, 2002.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.282
-
-
Yang, Z.1
Cerniway, R.J.2
Byford, A.M.3
Berr, S.S.4
French, B.A.5
Matherne, G.P.6
-
29
-
-
0032193692
-
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death
-
Virag L, Salzman AL and Szabó C: Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death. J Immunol 161: 3753-3759, 1998.
-
(1998)
J Immunol
, vol.161
, pp. 3753-3759
-
-
Virag, L.1
Salzman, A.L.2
Szabó, C.3
-
30
-
-
33646055216
-
The role of oxidants and free radicals in reperfusion injury
-
Zweier JL and Talukder MA: The role of oxidants and free radicals in reperfusion injury. Cardiovasc Res 70: 181-190, 2006.
-
(2006)
Cardiovasc Res
, vol.70
, pp. 181-190
-
-
Zweier, J.L.1
Talukder, M.A.2
-
31
-
-
0030828866
-
Diversity of dopamine receptors: New molecular and pharmacological developments
-
Hartman DS and Lanau F: Diversity of dopamine receptors: new molecular and pharmacological developments. Pol J Pharmacol 49: 191-199, 1997.
-
(1997)
Pol J Pharmacol
, vol.49
, pp. 191-199
-
-
Hartman, D.S.1
Lanau, F.2
-
32
-
-
33846905526
-
Recent progress in development of dopamine receptor subtype-selective agents: Potential therapeutics for neurological and psychiatric disorders
-
DOI 10.1021/cr050263h
-
Zhang A, Neumeyer JL and Baldessarini RJ: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders. Chem Rev 107: 274-302, 2007. (Pubitemid 46237370)
-
(2007)
Chemical Reviews
, vol.107
, Issue.1
, pp. 274-302
-
-
Zhang, A.1
Neumeyer, J.L.2
Baldessarini, R.J.3
-
33
-
-
13844276627
-
Target-based drug discovery: Is something wrong?
-
Sams-Dodd F: Target-based drug discovery: is something wrong? Drug Discov Today 10: 139-147, 2005.
-
(2005)
Drug Discov Today
, vol.10
, pp. 139-147
-
-
Sams-Dodd, F.1
-
34
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, Huang Z, Boyce M, et al: Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1: 112-119, 2005.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
-
35
-
-
0141646495
-
Target validation
-
Williams M: Target validation. Curr Opin Pharmacol 3: 571-577, 2003.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 571-577
-
-
Williams, M.1
-
37
-
-
9144274140
-
Utilizing small molecules in chemical genomics: Toward HT approaches
-
Darvas F, Guttman A and Dormán G (eds). Marcel Dekker, New York, Basel
-
Dormán G and Darvas F: Utilizing small molecules in chemical genomics: toward HT approaches. In: Chemical Genomics. Darvas F, Guttman A and Dormán G (eds). Marcel Dekker, New York, Basel, pp137-197, 2004.
-
(2004)
Chemical Genomics
, pp. 137-197
-
-
Dormán, G.1
Darvas, F.2
-
38
-
-
20844432908
-
Can cell systems biology rescue drug discovery?
-
Butcher EC: Can cell systems biology rescue drug discovery? Nat Rev Drug Discov 4: 461-467, 2005.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 461-467
-
-
Butcher, E.C.1
|