Oxygen-sensitive mitochondrial accumulation of cystathionine β-synthase mediated by Lon protease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 31, 2013, Pages 12679-12684

  Teng, Huajian ^a   Wu, Bo ^a,b   Zhao, Kexin ^a   Yang, Guangdong ^a   Wu, Lingyun ^a,c   Wang, Rui ^a  

^a LAKEHEAD UNIVERSITY   (Canada)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c Thunder Bay Regional Research Institute   (Canada)

Author keywords

Gasotransmitter; Hepatocytes; Mitochondrial swelling; Signaling; Transfection

Indexed keywords

CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; CYTOCHROME C; ENDOPEPTIDASE LA; HEAT SHOCK PROTEIN 70; HEME OXYGENASE 1; HYDROGEN SULFIDE; MITOCHONDRIAL PROTEIN; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOLIC FRACTION; DEOXYGENATION; HUMAN; HUMAN CELL; HYPOXIA; LIVER CELL; LIVER ISCHEMIA; LIVER MITOCHONDRION; MITOCHONDRIAL TARGETING SIGNAL; MITOCHONDRION SWELLING; NONHUMAN; OXYGEN TENSION; OXYGENATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; REOXYGENATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

GASOTRANSMITTER; HEPATOCYTES; MITOCHONDRIAL SWELLING; SIGNALING; TRANSFECTION;

ANIMALS; CYSTATHIONINE BETA-SYNTHASE; HEK293 CELLS; HEME; HEME OXYGENASE (DECYCLIZING); HUMANS; HYDROGEN SULFIDE; MALE; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTEINS; OXYGEN; PROTEASE LA; PROTEOLYSIS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 84881101982     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1308487110     Document Type: Article

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