Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 37, 2014, Pages E3880-E3889

  Sapir, Amir ^a,b   Tsur, Assaf ^c   Koorman, Thijs ^d   Ching, Kaitlin ^a,b   Mishra, Prashant ^a   Bardenheier, Annabelle ^a,b   Podolsky, Lisa ^c   Bening Abu Shach, Ulrike ^c   Boxem, Mike ^d   Chou, Tsui Fen ^e   Broday, Limor ^c   Sternberg, Paul W ^a,b  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d UTRECHT UNIVERSITY   (Netherlands)

^e HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LYSINE; MEVALONIC ACID; PROTEASOME; PROTEIN BINDING; UBIQUITIN;

AGING; ANIMAL; BIOLOGICAL MODEL; CAENORHABDITIS ELEGANS; CYTOSOL; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; MUTATION; PHENOTYPE; PHYSIOLOGY; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SUMOYLATION;

AGING; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CYTOSOL; HUMANS; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; LYSINE; METABOLIC NETWORKS AND PATHWAYS; MEVALONIC ACID; MITOCHONDRIA; MODELS, BIOLOGICAL; MUTATION; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN INTERACTION MAPS; PROTEIN TRANSPORT; SUMOYLATION; UBIQUITIN;

EID: 84907285707     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414748111     Document Type: Article

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