Structural basis for substrate specificity of mammalian neuraminidases

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Smutova, Victoria ^a   Albohy, Amgad ^b   Pan, Xuefang ^a   Korchagina, Elena ^c   Miyagi, Taeko ^d   Bovin, Nicolai ^c   Cairo, Christopher W ^b   Pshezhetsky, Alexey V ^a  

^a UNIVERSITY OF MONTREAL   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^d TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOSE; GLUCOSE; N ACETYLGLUCOSAMINE; NEURAMINIDASE 1; NEURAMINIDASE 2; NEURAMINIDASE 3; NEURAMINIDASE 4; OLIGOSACCHARIDE; SIALIDASE; UNCLASSIFIED DRUG; N ACETYLNEURAMINIC ACID;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SPECIFICITY; HYDROPHOBICITY; IN VITRO STUDY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN HYDROLYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; SUICIDE SUBSTRATE; ANIMAL; BRAIN; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; HYDROLYSIS; KINETICS; KNOCKOUT MOUSE; METABOLISM; PROTEIN TERTIARY STRUCTURE;

MAMMALIA;

ANIMALS; BINDING SITES; BRAIN; HYDROLYSIS; KINETICS; MICE, KNOCKOUT; MODELS, MOLECULAR; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

EID: 84907272228     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106320     Document Type: Article

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