STAT3-activated GM-CSFRα Translocates to the nucleus and protects CLL cells from apoptosis

Molecular Cancer Research

Volumn 12, Issue 9, 2014, Pages 1267-1282

  Li, Ping ^a   Harris, David ^a   Liu, Zhiming ^a   Rozovski, Uri ^a   Ferrajoli, Alessandra ^a   Wang, Yongtao ^a   Bueso Ramos, Carlos ^a   Hazan Halevy, Inbal ^a   Grgurevic, Srdana ^a   Wierda, William ^a   Burger, Jan ^a   O'Brien, Susan ^a   Faderl, Stefan ^a   Keating, Michael ^a   Estrov, Zeev ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; STAT3 PROTEIN; UNCLASSIFIED DRUG; CSF2RA PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BINDING SITE; CELL FRACTIONATION; CELL NUCLEUS; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CHRONIC LYMPHATIC LEUKEMIA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; PROMOTER REGION; GENE TRANSLOCATION; GENETICS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL SURVIVAL; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; NF-KAPPA B; PROMOTER REGIONS, GENETIC; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSLOCATION, GENETIC;

EID: 84907261386     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-13-0652-T     Document Type: Article

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