Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage

RNA

Volumn 20, Issue 10, 2014, Pages 1532-1538

  Hauptmann, Judith ^a   Kater, Lukas ^a   Löffler, Patrick ^a   Merkl, Rainer ^a   Meister, Gunter ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Ago4; Argonaute proteins; Gene silencing; MicroRNAs; RNAi; SiRNAs

Indexed keywords

ARGONAUTE 1 PROTEIN; ARGONAUTE 2 PROTEIN; ARGONAUTE 3 PROTEIN; ARGONAUTE 4 PROTEIN; ARGONAUTE PROTEIN; MICRORNA; UNCLASSIFIED DRUG; EIF2C2 PROTEIN, HUMAN; EIF2C4 PROTEIN, HUMAN; INITIATION FACTOR; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CATALYSIS; EMBRYO; HEK293 CELL LINE; IN VITRO STUDY; MOUSE; NONHUMAN; PHYLOGENETIC TREE; PHYLOGENY; PROTEIN DOMAIN; PROTEIN EXPRESSION; RNA BINDING; RNA CLEAVAGE; RNA STRUCTURE; SEQUENCE ANALYSIS; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NORTHERN BLOTTING; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ARGONAUTE PROTEINS; BLOTTING, NORTHERN; CATALYSIS; EUKARYOTIC INITIATION FACTORS; HEK293 CELLS; HUMANS; MICRORNAS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHYLOGENY; PROTEIN CONFORMATION; RNA CLEAVAGE; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84907217760     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.045203.114     Document Type: Article

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