-
4
-
-
2942536634
-
Drug delivery systems for vitreoretinal diseases
-
Yasukawa T, Ogura Y, Tabata Y, et al. Drug delivery systems for vitreoretinal diseases. Prog Retin Eye Res 2004;23:253-81
-
(2004)
Prog Retin Eye Res
, vol.23
, pp. 253-281
-
-
Yasukawa, T.1
Ogura, Y.2
Tabata, Y.3
-
5
-
-
0033895534
-
Retinal and choroidal neovascularization
-
Campochiaro P. Retinal and choroidal neovascularization. J Cell Physiol 2000;184:201-10
-
(2000)
J Cell Physiol
, vol.184
, pp. 201-210
-
-
Campochiaro, P.1
-
6
-
-
57949094834
-
Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Twoyear results of the ANCHOR study
-
Brown DM, Michels M, Kaiser PK, et al. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Twoyear results of the ANCHOR study. Ophthalmology 2009;116:57-65
-
(2009)
Ophthalmology
, vol.116
, pp. 57-65
-
-
Brown, D.M.1
Michels, M.2
Kaiser, P.K.3
-
7
-
-
68249126178
-
Intravitreal injection of therapeutic agents
-
Peyman GA, Lad EM, Moshfeghi DM. Intravitreal injection of therapeutic agents. Retina 2009;29:875-912
-
(2009)
Retina
, vol.29
, pp. 875-912
-
-
Peyman, G.A.1
Lad, E.M.2
Moshfeghi, D.M.3
-
9
-
-
28444444139
-
Topical and systemic drug delivery to the posterior segments
-
Hughes PM, Olejnik O, Chang-Lin JE, et al. Topical and systemic drug delivery to the posterior segments. Adv Drug Deliv Rev 2005;57:2010-32
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 2010-2032
-
-
Hughes, P.M.1
Olejnik, O.2
Chang-Lin, J.E.3
-
11
-
-
0022852854
-
Topical ocular drug delivery: Recent developments and future challenges
-
Lee VHL, Robinson JR. Topical ocular drug delivery: Recent developments and future challenges. J Ocul Pharmacol Ther 1986;2:67-108
-
(1986)
J Ocul Pharmacol Ther
, vol.2
, pp. 67-108
-
-
Vhl, L.1
Robinson, J.R.2
-
12
-
-
0344286485
-
Cyclodextrins in ophthalmic drug delivery
-
Loftssona T, Järvinen T. Cyclodextrins in ophthalmic drug delivery. Adv Drug Deliv Rev 1999;36:59-79
-
(1999)
Adv Drug Deliv Rev
, vol.36
, pp. 59-79
-
-
Loftssona, T.1
Järvinen, T.2
-
13
-
-
34447313299
-
Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye
-
Sigurdsson HH, Konrá-sdóttir F, Loftsson T, et al. Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye. Acta Ophthalmol Scand 2007;85:598-602
-
(2007)
Acta Ophthalmol Scand
, vol.85
, pp. 598-602
-
-
Sigurdsson, H.H.1
Konrá-sdóttir, F.2
Loftsson, T.3
-
14
-
-
70350769565
-
Current ocular drug delivery challenges for n-Acetylcarnosine: Novel patented routes and modes of delivery, design for enhancement of therapeutic activity and drug delivery relationships
-
Babizhayev MA. Current ocular drug delivery challenges for n-Acetylcarnosine: Novel patented routes and modes of delivery, design for enhancement of therapeutic activity and drug delivery relationships. Recent Pat Drug Deliv Formul 2009;3:229-65
-
(2009)
Recent Pat Drug Deliv Formul
, vol.3
, pp. 229-265
-
-
Babizhayev, M.A.1
-
15
-
-
84897880819
-
Contact lenses for antifungal ocular drug delivery: A review
-
Phan CM, Subbaraman L, Jones L. Contact lenses for antifungal ocular drug delivery: A review. Expert Opin Drug Deliv 2014;11:537-46
-
(2014)
Expert Opin Drug Deliv
, vol.11
, pp. 537-546
-
-
Phan, C.M.1
Subbaraman, L.2
Jones, L.3
-
16
-
-
84555187190
-
Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edema
-
Tanito M, Kara K, Takai Y, et al. Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edema. Invest Ophthalmol Vis Sci 2011;52:7944-8
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 7944-7948
-
-
Tanito, M.1
Kara, K.2
Takai, Y.3
-
17
-
-
84907193403
-
-
College of Medicine; King Saud University. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD) Available from [Cited 12 March 2014] NLM Identifier NCT01523314
-
College of Medicine; King Saud University. Topical dexamethasone-cyclodextrin microparticle eye drops for diabetic macular edema (DECEDE). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01523314 [Cited 12 March 2014] NLM Identifier NCT01523314
-
(2000)
Topical Dexamethasone-cyclodextrin Microparticle Eye Drops for Diabetic Macular Edema (DECEDE)
-
-
-
19
-
-
52049087662
-
Molecular design for enhancement of ocular penetration
-
Shirasaki Y. Molecular design for enhancement of ocular penetration. J Pharm Sci 2008;97:2462-96
-
(2008)
J Pharm Sci
, vol.97
, pp. 2462-2496
-
-
Shirasaki, Y.1
-
20
-
-
84858157691
-
In vivo characterisation of a novel water-soluble cyclosporine A prodrug for the treatment of dry eye disease
-
Rodriguez-Aller M, Kaufmann B, Guillarme D, et al. In vivo characterisation of a novel water-soluble cyclosporine A prodrug for the treatment of dry eye disease. Eur J Pharm Biopharm 2012;80:544-52
-
(2012)
Eur J Pharm Biopharm
, vol.80
, pp. 544-552
-
-
Rodriguez-Aller, M.1
Kaufmann, B.2
Guillarme, D.3
-
21
-
-
0032410376
-
Comparison of the ocular distribution of a model oligonucleotide after topical instillation in rabbits of conventional and new dosage forms
-
Bochot A, Mashhour B, Puisieux F, et al. Comparison of the ocular distribution of a model oligonucleotide after topical instillation in rabbits of conventional and new dosage forms. J Drug Target 1998;6:309-13
-
(1998)
J Drug Target
, vol.6
, pp. 309-313
-
-
Bochot, A.1
Mashhour, B.2
Puisieux, F.3
-
22
-
-
84898638408
-
Topical delivery of avastin to the posterior segment of the eye in vivo using annexin A5-Associated liposomes
-
Davis BM, Normando EM, Guo L, et al. Topical delivery of avastin to the posterior segment of the eye in vivo using annexin A5-Associated liposomes. Small 2014;10:1575-84
-
(2014)
Small
, vol.10
, pp. 1575-1584
-
-
Davis, B.M.1
Normando, E.M.2
Guo, L.3
-
23
-
-
0034624078
-
Structure of membrane-bound annexin A5 trimers: A hybrid cryo-EM-x-ray crystallography study
-
Oling F, Santos JS, Govorukhina N, et al. Structure of membrane-bound annexin A5 trimers: A hybrid cryo-EM-x-ray crystallography study. J Mol Biol 2000;304:561-73
-
(2000)
J Mol Biol
, vol.304
, pp. 561-573
-
-
Oling, F.1
Santos, J.S.2
Govorukhina, N.3
-
24
-
-
79951965818
-
Ocular distribution of difluprednate ophthalmic emulsion 0.05% in rabbits
-
Tajika T, Isowaki A, Sakaki H. Ocular distribution of difluprednate ophthalmic emulsion 0.05% in rabbits. J Ocul Pharmacol Ther 2011;27:43-9
-
(2011)
J Ocul Pharmacol Ther
, vol.27
, pp. 43-49
-
-
Tajika, T.1
Isowaki, A.2
Sakaki, H.3
-
25
-
-
84868111418
-
Treatment of diffuse diabetic macular oedema using steroid eye drops
-
Nakano Goto S, Yamamoto T, Kirii E, et al. Treatment of diffuse diabetic macular oedema using steroid eye drops. Acta Ophthalmol 2012;90:629-32
-
(2012)
Acta Ophthalmol
, vol.90
, pp. 629-632
-
-
Nakano Goto, S.1
Yamamoto, T.2
Kirii, E.3
-
26
-
-
77952095945
-
Steroid eye drop treatment (difluprednate ophthalmic emulsion) is effective in reducing refractory diabetic macular edema
-
Nakano S, Yamamoto T, Kirii E, et al. Steroid eye drop treatment (difluprednate ophthalmic emulsion) is effective in reducing refractory diabetic macular edema. Graefes Arch Clin Exp Ophthalmol 2010;248:805-10
-
(2010)
Graefes Arch Clin Exp Ophthalmol
, vol.248
, pp. 805-810
-
-
Nakano, S.1
Yamamoto, T.2
Kirii, E.3
-
27
-
-
84907187121
-
-
Ocular Therapeutix Inc. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). Available from 25 March 2014] NLM Identifier NCT01666210
-
Ocular Therapeutix, Inc. Phase II study evaluating safety/efficacy of OTX-DP for treatment of ocular inflammation and pain after cataract surgery. In: ClinicalTrials.gov [Internet]. Bethesda (MD): National Library of Medicine (US). 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01666210 [cited 25 March 2014] NLM Identifier NCT01666210
-
(2000)
Phase II Study Evaluating Safety/efficacy of OTX-DP for Treatment of Ocular Inflammation and Pain after Cataract Surgery
-
-
-
28
-
-
84907203563
-
-
Ocular Therapeutix Inc Bedford MA. Available from [Last accessed 29 April 2014]
-
Dexamethasone Punctum Plug. Ocular Therapeutix, Inc., Bedford, MA; 2014. Available from: Www.ocutx.com/pipeline/dexamethasone-punctum-plug [Last accessed 29 April 2014]
-
(2014)
Dexamethasone Punctum Plug
-
-
-
29
-
-
84907193402
-
Multi-center evaluation of safety and efficacy of sustained-release dexamethasone after cataract surgery
-
The Annual ASCRS and ASOA Symposium and Congress 27 April 2014; Boston, MA 30. Pipeline. Ocular Therapeutix, Inc., Bedford, MA Available from accessed 29 April 2014]
-
Endl MJ, Levenson JH, Walters TR, et al. Multi-center evaluation of safety and efficacy of sustained-release dexamethasone after cataract surgery, in: Intraocular Surgery Medications. The Annual ASCRS and ASOA Symposium and Congress; 27 April 2014; Boston, MA 30. Pipeline. Ocular Therapeutix, Inc., Bedford, MA; 2014. Available from: Www.ocutx.com/pipeline [Last accessed 29 April 2014]
-
(2014)
Intraocular Surgery Medications
-
-
Endl, M.J.1
Levenson, J.H.2
Walters, T.R.3
-
31
-
-
84870948029
-
Hydrogel contact lens for extended delivery of ophthalmic drugs
-
Hu X, Hao L, Wang H, et al. Hydrogel contact lens for extended delivery of ophthalmic drugs. Int J Polym Sci 2011;2011:1-9
-
(2011)
Int J Polym Sci
, vol.2011
, pp. 1-9
-
-
Hu, X.1
Hao, L.2
Wang, H.3
-
32
-
-
33745964142
-
Verteporfin: A review of its use in the management of subfoveal choroidal neovascularization
-
Fenton C, Perry CM. Verteporfin: A review of its use in the management of subfoveal choroidal neovascularization. Drug Aging 2006;23:421-45
-
(2006)
Drug Aging
, vol.23
, pp. 421-445
-
-
Fenton, C.1
Perry, C.M.2
-
33
-
-
0036822175
-
Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: Threeyear results of an open-label extension of 2 randomized clinical trials-TAP
-
report no
-
Blumenkranz MS, Bressler NM, Bressler SB, et al. Verteporfin therapy for subfoveal choroidal neovascularization in age-related macular degeneration: Threeyear results of an open-label extension of 2 randomized clinical trials-TAP report no. 5. Arch Ophthalmol 2002;120:1307-14
-
(2002)
5. Arch Ophthalmol
, vol.120
, pp. 1307-1314
-
-
Blumenkranz, M.S.1
Bressler, N.M.2
Bressler, S.B.3
-
35
-
-
1542742166
-
Reduction of diabetic macular edema by oral administration of the kinase inhibitor PKC412
-
The C99-PKC412-003 Study Group.
-
Campochiaro PA; The C99-PKC412-003 Study Group. Reduction of diabetic macular edema by oral administration of the kinase inhibitor PKC412. Invest Ophthalmol Vis Sci 2004;45:922-31
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 922-931
-
-
Campochiaro, P.A.1
-
36
-
-
0142231905
-
Periocular injection of microspheres containing PKC412 inhibits choroidal neovascularization in a porcine model
-
Saishin Y, Silva RL, Saishin Y, et al. Periocular injection of microspheres containing PKC412 inhibits choroidal neovascularization in a porcine model. Invest Ophthalmol Vis Sci 2003;44:4989-93
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 4989-4993
-
-
Saishin, Y.1
Silva, R.L.2
Saishin, Y.3
-
37
-
-
44349161777
-
Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina
-
Golczak M, Maeda A, Bereta G, et al. Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina. J Biol Chem 2008;283:9543-54
-
(2008)
J Biol Chem
, vol.283
, pp. 9543-9554
-
-
Golczak, M.1
Maeda, A.2
Bereta, G.3
-
38
-
-
77954958266
-
Visual cycle modulation in neurovascular retinopathy
-
Akula JD, Hansen RM, Tzekov R, et al. Visual cycle modulation in neurovascular retinopathy. Exp Eye Res 2010;91:153-61
-
(2010)
Exp Eye Res
, vol.91
, pp. 153-161
-
-
Akula, J.D.1
Hansen, R.M.2
Tzekov, R.3
-
39
-
-
84894473858
-
Phase 1, doseranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers
-
Kubota R, Al-Fayoumi S, Mallikaarjun S, et al. Phase 1, doseranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers. Retina 2014;34:603-9
-
(2014)
Retina
, vol.34
, pp. 603-609
-
-
Kubota, R.1
Al-Fayoumi, S.2
Mallikaarjun, S.3
-
40
-
-
0036510535
-
Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin
-
Ben-Shabat S, Parish CA, Vollmer HR, et al. Biosynthetic studies of A2E, a major fluorophore of retinal pigment epithelial lipofuscin. J Biol Chem 2002;277:7183-90
-
(2002)
J Biol Chem
, vol.277
, pp. 7183-7190
-
-
Ben-Shabat, S.1
Parish, C.A.2
Vollmer, H.R.3
-
42
-
-
0035289188
-
Prodrug based optimal drug delivery via membrane transporter/receptor
-
Yang C, Tirucherai GS, Mitra AK. Prodrug based optimal drug delivery via membrane transporter/receptor. Expert Opin Biol Ther 2001;1:159-75
-
(2001)
Expert Opin Biol Ther
, vol.1
, pp. 159-175
-
-
Yang, C.1
Tirucherai, G.S.2
Mitra, A.K.3
-
43
-
-
35048821557
-
Transport barriers in transscleral drug delivery for retinal diseases
-
Kim S, Lutz R, Wang N, et al. Transport barriers in transscleral drug delivery for retinal diseases. Ophthalmic Res 2007;39:244-54
-
(2007)
Ophthalmic Res
, vol.39
, pp. 244-254
-
-
Kim, S.1
Lutz, R.2
Wang, N.3
-
44
-
-
28444440585
-
Recent progress in ocular drug delivery for posterior segment disease: Emphasis on transcleral iontophoresis
-
Myles ME, Neumann DM, Hill JM. Recent progress in ocular drug delivery for posterior segment disease: Emphasis on transcleral iontophoresis. Adv Drug Deliv Rev 2005;57:2063-79
-
(2005)
Adv Drug Deliv Rev
, vol.57
, pp. 2063-2079
-
-
Myles, M.E.1
Neumann, D.M.2
Hill, J.M.3
-
45
-
-
23944493904
-
Transcorneal and transscleral iontophoresis of dexamethasone phosphate using drug loaded hydrogel
-
Eljarrat-Binstock E, Raiskup F, Frucht-Pery J, et al. Transcorneal and transscleral iontophoresis of dexamethasone phosphate using drug loaded hydrogel. J Control Release 2005;106:386-90
-
(2005)
J Control Release
, vol.106
, pp. 386-390
-
-
Eljarrat-Binstock, E.1
Raiskup, F.2
Frucht-Pery, J.3
-
46
-
-
84855320097
-
Evaluation of dexamethasone phosphate delivered by ocular iontophoresis for treating noninfectious anterior uveitis
-
Cohen AE, Assang C, Patane MA, et al. Evaluation of dexamethasone phosphate delivered by ocular iontophoresis for treating noninfectious anterior uveitis. Ophthalmology 2012;119:66-73
-
(2012)
Ophthalmology
, vol.119
, pp. 66-73
-
-
Cohen, A.E.1
Assang, C.2
Ma, P.3
-
47
-
-
79957467372
-
Ocular iontophoresis of EGP-437 (dexamethasone phosphate) in dry eye patients: Results of a randomized clinical trial
-
Patane MA, Cohen A, From S, et al. Ocular iontophoresis of EGP-437 (dexamethasone phosphate) in dry eye patients: Results of a randomized clinical trial. Clin Ophthalmol 2011;5:633-43
-
(2011)
Clin Ophthalmol
, vol.5
, pp. 633-643
-
-
Ma, P.1
Cohen, A.2
From, S.3
-
48
-
-
84907215189
-
-
Department of Ophthalmology and Epidemiology University of Pennsylvania In: Clinical Trials.gov [Internet]. National Library of Medicine (US), Bethesda (MD) Available from [Cited 21 March 2014] NLM Identifier NCT01059955
-
Department of Ophthalmology and Epidemiology; University of Pennsylvania. Iontophoresis delivery of dexamethasone phosphate for noninfectious, non-necrotizing anterior scleritis, phase 1 dose-varying study. In: Clinical Trials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01059955 [Cited 21 March 2014] NLM Identifier NCT01059955
-
(2000)
Iontophoresis Delivery of Dexamethasone Phosphate for Noninfectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study
-
-
-
49
-
-
84907193401
-
-
Available from [Last accessed 29 April 2014]
-
Pipeline. Eyegate Pharmaceuticals, Inc., Waltham, MA. 2013. Available from: Www.eyegatepharma.com/therapeutics/pipeline5.html [Last accessed 29 April 2014]
-
(2013)
Pipeline. Eyegate Pharmaceuticals Inc Waltham M.A.
-
-
-
50
-
-
84907223987
-
-
In: Development of Sustained Delivery Lucentis. Genentech, Inc., South San Francisco, CA. Available from [Last accessed 21 March 2014]
-
Genentech Announces First Milestone Payment to Device-Maker ForSight VISION4, Inc. In: Development of Sustained Delivery Lucentis. Genentech, Inc., South San Francisco, CA. 2012. Available from: Www.gene.com/media/press-releases/13808/2012-01-13/genentech-Announces-first-milestonepaym [Last accessed 21 March 2014]
-
(2012)
Genentech Announces First Milestone Payment to Device-Maker ForSight VISION4, Inc
-
-
-
51
-
-
84907208307
-
-
Forsight Vision4. In: ClinicalTrials. gov [Internet]. National Library of Medicine (US), Bethesda (MD) Available from [Cited 21 Mar 2014] NLM Identifier NCT01186432
-
Forsight Vision4. Preliminary safety and efficacy of the PDS-1.0 in patients with neovascular age related macular degeneration (AMD). In: ClinicalTrials. gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials. gov/ct2/show/NCT01186432 [Cited 21 Mar 2014] NLM Identifier NCT01186432
-
(2000)
Preliminary Safety and Efficacy of the PDS-1.0 in Patients with Neovascular Age Related Macular Degeneration (AMD)
-
-
-
53
-
-
0034059710
-
Intraocular penetration of vancomycin eye drops after application to the medial canthus with closed lids
-
Alster Y, Herlin L, Lazar M, et al. Intraocular penetration of vancomycin eye drops after application to the medial canthus with closed lids. Br J Ophthalmol 2000;84:300-2
-
(2000)
Br J Ophthalmol
, vol.84
, pp. 300-302
-
-
Alster, Y.1
Herlin, L.2
Lazar, M.3
-
54
-
-
84907203562
-
-
Santen Pharmaceutical Co Ltd. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US) Bethesda (MD) Available from [Cited 25 Mar 2014] NLM Identifier NCT01411254
-
Santen Pharmaceutical Co., Ltd. Efficacy and safety of betamethasone microsphere in patients with diabetic macular wdema (TSUBASA). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01411254 [Cited 25 Mar 2014] NLM Identifier NCT01411254
-
(2000)
Efficacy and Safety of Betamethasone Microsphere in Patients with Diabetic Macular Wdema (TSUBASA)
-
-
-
55
-
-
84907193400
-
-
Santen Pharmaceutical Co Ltd. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US) Bethesda (MD) Available from [Cited 25 Mar 2014] NLM Identifier NCT01512901
-
Santen Pharmaceutical Co., Ltd. Efficacy and safety of betamethasone microsphere in patients with macular edema following branch retinal vein occlusion (HIKARI). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01512901 [Cited 25 Mar 2014] NLM Identifier NCT01512901
-
(2000)
Efficacy and Safety of Betamethasone Microsphere in Patients with Macular Edema Following Branch Retinal Vein Occlusion (HIKARI)
-
-
-
56
-
-
47749100898
-
Conducting clinical trials: Even more challenges
-
Novack GD. Conducting clinical trials: Even more challenges. Ocul Surf 2008;6:99-101
-
(2008)
Ocul Surf
, vol.6
, pp. 99-101
-
-
Novack, G.D.1
-
57
-
-
84907223704
-
-
Oakwood Laboratories LLC. Oakwood Village OH,. Available from [Last accessed 25 March 2014]
-
Chroniject-Technology. Oakwood Laboratories, LLC., Oakwood Village, OH, 2014. Available from: Www.oakwoodlabs.com/technology/index. php [Last accessed 25 March 2014]
-
(2014)
Chroniject-Technology
-
-
-
58
-
-
34250710927
-
Canaloplasty: Circumferential viscodilation and tensioning of Schlemm's canal using a flexible microcatheter for the treatment of openangle glaucoma in adults: Interim clinical study analysis
-
Lewis RA, von Wolff K, Tetz M, et al. Canaloplasty: Circumferential viscodilation and tensioning of Schlemm's canal using a flexible microcatheter for the treatment of openangle glaucoma in adults: Interim clinical study analysis. J Cataract Refract Surg 2007;33:1217-26
-
(2007)
J Cataract Refract Surg
, vol.33
, pp. 1217-1226
-
-
Lewis, R.A.1
Von Wolff, K.2
Tetz, M.3
-
59
-
-
33750086968
-
Cannulation of the suprachoroidal space: A novel drug delivery methodology to the posterior segment
-
Olsen TW, Feng X, Wabner K, et al. Cannulation of the suprachoroidal space: A novel drug delivery methodology to the posterior segment. Am J Ophthalmol 2006;142:777-87
-
(2006)
Am J Ophthalmol
, vol.142
, pp. 777-787
-
-
Olsen, T.W.1
Feng, X.2
Wabner, K.3
-
60
-
-
80052385883
-
Pharmacokinetics of pars plana intravitreal injections versus microcannula suprachoroidal injections of bevacizumab in a porcine model
-
Olsen TW, Feng X, Wabner K, et al. Pharmacokinetics of pars plana intravitreal injections versus microcannula suprachoroidal injections of bevacizumab in a porcine model. Invest Ophthalmol Vis Sci 2011;52:4749-56
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 4749-4756
-
-
Olsen, T.W.1
Feng, X.2
Wabner, K.3
-
61
-
-
84860452674
-
Safety of submacular suprachoroidal drug administration via a microcatheter: Retrospective analysis of European treatment results
-
Tetz M, Rizzo S, Augustin AJ. Safety of submacular suprachoroidal drug administration via a microcatheter: Retrospective analysis of European treatment results. Ophthalmologica 2012;227:183-9
-
(2012)
Ophthalmologica
, vol.227
, pp. 183-189
-
-
Tetz, M.1
Rizzo, S.2
Augustin, A.J.3
-
62
-
-
84859100882
-
Suprachoroidal drug infusion for the treatment of severe subfoveal hard exudates
-
Rizzo S, Ebert FG, Bartolo ED, et al. Suprachoroidal drug infusion for the treatment of severe subfoveal hard exudates. Retina 2012;32:776-84
-
(2012)
Retina
, vol.32
, pp. 776-784
-
-
Rizzo, S.1
Ebert, F.G.2
Bartolo, E.D.3
-
63
-
-
84907189363
-
-
Janssen Research & Development, LLC. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD) Available from [Cited 29 April 2014] NLM Identifier NCT01226628
-
Janssen Research & Development, LLC. A safety study of CNTO 2476 in patients with age-related macular degeneration. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials. gov/ct2/show/NCT01226628 [Cited 29 April 2014] NLM Identifier NCT01226628
-
(2000)
A Safety Study of CNTO 2476 in Patients with Age-related Macular Degeneration
-
-
-
64
-
-
78651245667
-
Suprachoroidal drug delivery to the back of the eye using hollow microneedles
-
Patel SR, Lin AS, Edelhauser HF, et al. Suprachoroidal drug delivery to the back of the eye using hollow microneedles. Pharm Res 2011;28:166-76
-
(2011)
Pharm Res
, vol.28
, pp. 166-176
-
-
Patel, S.R.1
Lin, A.S.2
Edelhauser, H.F.3
-
65
-
-
33751268869
-
Intraocular implants for extended drug delivery: Therapeutic applications
-
Bourges J, Bloquel C, Thomas A, et al. Intraocular implants for extended drug delivery: Therapeutic applications. Adv Drug Deliv Rev 2006;58:1182-202
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 1182-1202
-
-
Bourges, J.1
Bloquel, C.2
Thomas, A.3
-
66
-
-
33749445317
-
Ranibizumab for neovascular agerelated macular degeneration
-
Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular agerelated macular degeneration. N Engl J Med 2006;355:1419-31
-
(2006)
N Engl J Med
, vol.355
, pp. 1419-1431
-
-
Rosenfeld, P.J.1
Brown, D.M.2
Heier, J.S.3
-
67
-
-
79955085045
-
Pharmacotherapy for neovascular age-related macular degeneration: An analysis of the 100% 2008 Medicare fee-for-service part B claims file
-
Brechner RJ, Rosenfeld PJ, Babish JD, et al. Pharmacotherapy for neovascular age-related macular degeneration: An analysis of the 100% 2008 Medicare fee-for-service part B claims file. Am J Ophthalmol 2011;151:887-95
-
(2011)
Am J Ophthalmol
, vol.151
, pp. 887-895
-
-
Brechner, R.J.1
Rosenfeld, P.J.2
Babish, J.D.3
-
68
-
-
84863320414
-
Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration
-
Martin DF, Maguire MG, Fine SL, et al. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration. Ophthalmology 2012;119:1388-98
-
(2012)
Ophthalmology
, vol.119
, pp. 1388-1398
-
-
Martin, D.F.1
Maguire, M.G.2
Fine, S.L.3
-
69
-
-
74949119167
-
Phase i study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors
-
Lockhart AC, Rothenberg ML, Dupont J, et al. Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors. J Clin Oncol 2010;28:207-14
-
(2010)
J Clin Oncol
, vol.28
, pp. 207-214
-
-
Lockhart, A.C.1
Rothenberg, M.L.2
Dupont, J.3
-
70
-
-
84870723704
-
Intravitreal aflibercept (VEGF Trap-Eye) in wet age-related macular degeneration
-
Heier JS, Brown DM, Chong V, et al. Intravitreal aflibercept (VEGF Trap-Eye) in wet age-related macular degeneration. Ophthalmology 2012;119:2537-48
-
(2012)
Ophthalmology
, vol.119
, pp. 2537-2548
-
-
Heier, J.S.1
Brown, D.M.2
Chong, V.3
-
71
-
-
84891631034
-
Intravitreal aflibercept injection for neovascular agerelated macular degeneration
-
Schmidt-Erfurth U, Kaiser PK, Korobelnik JF, et al. Intravitreal aflibercept injection for neovascular agerelated macular degeneration. Ophthalmology 2014;121:193-201
-
(2014)
Ophthalmology
, vol.121
, pp. 193-201
-
-
Schmidt-Erfurth, U.1
Kaiser, P.K.2
Korobelnik, J.F.3
-
72
-
-
84873738185
-
Intravitreal aflibercept injection for macular edema secondary to central retinal vein occlusion: 1-year results from the phase 3 COPERNICUS study
-
Brown DM, Heier JS, Clark WL, et al. Intravitreal aflibercept injection for macular edema secondary to central retinal vein occlusion: 1-year results from the phase 3 COPERNICUS study. Am J Ophthalmol 2013;155:429-37
-
(2013)
Am J Ophthalmol
, vol.155
, pp. 429-437
-
-
Brown, D.M.1
Heier, J.S.2
Clark, W.L.3
-
73
-
-
84907198824
-
-
Bayer. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD) Available fromCited 29 April 2014] NLM Identifier NCT01331681
-
Bayer. VEGF trap-eye in vision impairment due to DME (VIVIDDME). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials. gov/ct2/show/NCT01331681 [Cited 29 April 2014] NLM Identifier NCT01331681
-
(2000)
VEGF Trap-eye in Vision Impairment Due to DME (VIVIDDME)
-
-
-
74
-
-
84907223703
-
-
Regeneron Pharmaceuticals In: ClinicalTrials.gov [Internet]. National Library of Medicine (US) Bethesda (MD) Available fromCited 29 April 2014] NLM Identifier NCT01363440
-
Regeneron Pharmaceuticals. Study of intravitreal administration of VEGF trap-eye (BAY86-5321) in patients with diabetic macular edema (VISTA DME). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01363440 [Cited 29 April 2014] NLM Identifier NCT01363440
-
(2000)
Study of Intravitreal Administration of VEGF Trap-eye (BAY86-5321) in Patients with Diabetic Macular Edema (VISTA DME)
-
-
-
75
-
-
84907213482
-
-
Bayer. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US) Bethesda (MD) Available from [Cited 29 April 2014] NLM Identifier NCT01783886
-
Bayer. Efficacy and safety of VEGF trap eye in diabetic macular edema (DME) with central involvement (VIVID EAST). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01783886 [Cited 29 April 2014] NLM Identifier NCT01783886
-
(2000)
Efficacy and Safety of VEGF Trap Eye in Diabetic Macular Edema (DME) with Central Involvement (VIVID EAST)
-
-
-
76
-
-
84907223702
-
-
New York NY. Available from [Last accessed 24 March 2014]
-
Fovista-. Ophtotech Co. New York, NY; 2014. Available from: Www.ophthotech.com/productcandidates/fovista/[Last accessed 24 March 2014]
-
(2014)
Fovista-Ophtotech Co
-
-
-
77
-
-
84907208505
-
-
Ophthotech Corp. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US) Bethesda (MD) Available from [Cited 24 March 2014] NLM Identifier NCT01089517
-
Ophthotech Corp. A safety and efficacy study of E10030 (anti-PDGF pegylated aptamer) plus Lucentis for neovascular age-related macular degeneration. In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01089517 [Cited 24 March 2014] NLM Identifier NCT01089517
-
(2000)
A Safety and Efficacy Study of E10030 (Anti-PDGF Pegylated Aptamer) Plus Lucentis for Neovascular Age-related Macular Degeneration
-
-
-
80
-
-
79952990684
-
A novel sustained-release intravitreal drug delivery system for retinal vascular disease
-
Fung AE. A novel sustained-release intravitreal drug delivery system for retinal vascular disease. Retin Today 2010;51-3
-
(2010)
Retin Today
, pp. 51-53
-
-
Fung, A.E.1
-
82
-
-
84907203561
-
-
University of Illinois-Chicago Eye and Ear Infirmary In: ClinicalTrials.gov [Internet]. National Library of Medicine (US) Bethesda (MD) Available from 17 Mar 2014] NLM Identifier NCT01175395
-
University of Illinois-Chicago Eye and Ear Infirmary. 20089 TA+Lucentis combo intravitreal injections for treatment of neovascular age-related macular degeneration (AMD) (20089/Combo). In: ClinicalTrials.gov [Internet]. National Library of Medicine (US), Bethesda (MD); 2000. Available from: Www.clinicaltrials.gov/ct2/show/NCT01175395 [Cited 17 Mar 2014] NLM Identifier NCT01175395
-
A 20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) (20089/Combo)
-
-
-
83
-
-
84907223701
-
-
IBI-10090. Available from [Last accessed 17 March 2014]
-
IBI-10090. Icon Bioscience, Inc., Sunnyvale, CA; 2014. Available from: Www.iconbioscience.com/ibi-10090 [Last accessed 17 March 2014]
-
(2014)
Icon Bioscience, Inc., Sunnyvale, CA
-
-
-
84
-
-
0033104581
-
Visual and anatomic outcomes associated with posterior segment complications after ganciclovir implant procedures in patients with AIDS and cytomegalovirus retinitis
-
Lim JI, Wolitz RA, Dowling AH, et al. Visual and anatomic outcomes associated with posterior segment complications after ganciclovir implant procedures in patients with AIDS and cytomegalovirus retinitis. Am J Ophthalmol 1999;127:288-93
-
(1999)
Am J Ophthalmol
, vol.127
, pp. 288-293
-
-
Lim, J.I.1
Wolitz, R.A.2
Dowling, A.H.3
-
85
-
-
3042763334
-
Ocular pharmacokinetics of fluocinolone acetonide after Retisert-intravitreal implantation in rabbits over a 1-year period
-
Driot JY, Novack GD, Rittenhouse KD, et al. Ocular pharmacokinetics of fluocinolone acetonide after Retisert-intravitreal implantation in rabbits over a 1-year period. J Ocul Pharmacol Ther 2004;20:269-75
-
(2004)
J Ocul Pharmacol Ther
, vol.20
, pp. 269-275
-
-
Driot, J.Y.1
Novack, G.D.2
Rittenhouse, K.D.3
-
86
-
-
53249147453
-
NT-501: An ophthalmic implant of polymerencapsulated ciliary neurotrophic factor-producing cells
-
Emerich DF, Thanos C. NT-501: An ophthalmic implant of polymerencapsulated ciliary neurotrophic factor-producing cells. Curr Opin Mol Ther 2008;10:506-15
-
(2008)
Curr Opin Mol Ther
, vol.10
, pp. 506-515
-
-
Emerich, D.F.1
Thanos, C.2
-
87
-
-
33746059820
-
Application of encapsulated cell technology for retinal degenerative diseases
-
Tao W. Application of encapsulated cell technology for retinal degenerative diseases. Expert Opin Biol Ther 2006;6:717-26
-
(2006)
Expert Opin Biol Ther
, vol.6
, pp. 717-726
-
-
Tao, W.1
-
88
-
-
33644872951
-
Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase i trial of CNTF delivered by encapsulated cell intraocular implants
-
Sieving PA, Caruso RC, Tao W, et al. Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants. Proc Natl Acad Sci USA 2006;103:3896-901
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3896-3901
-
-
Sieving, P.A.1
Caruso, R.C.2
Tao, W.3
-
89
-
-
84907213481
-
-
ECT Pipeline Cumberland RI. Available fromLast accessed 19 March 2014]
-
ECT Pipeline. Neurotech Pharmaceuticals, Inc., Cumberland, RI; 2012. Available from: Www.neurotechusa. com/ect-pipeline.html [Last accessed 19 March 2014]
-
(2012)
Neurotech Pharmaceuticals Inc
-
-
-
90
-
-
21444461055
-
Long-Term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis
-
Jaffe GJ, McCallum RM, Branchaud B, et al. Long-Term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis. Ophthalmology 2005;112:1192-8
-
(2005)
Ophthalmology
, vol.112
, pp. 1192-1198
-
-
Jaffe, G.J.1
McCallum, R.M.2
Branchaud, B.3
-
91
-
-
84907209295
-
-
Bausch & Lomb, Inc., Rochester, NY Available fromLast accessed 18 March 2014]
-
Retisert (fluocinolone acetonide intravitreal implant) 0.59 mg. Bausch & Lomb, Inc., Rochester, NY; 2014. Available from: Www.bausch.com/en/ecp/our-products/rx-pharmaceuticals/rxpharmaceuticals-ecp/retisert/[Last accessed 18 March 2014]
-
(2014)
Retisert (Fluocinolone Acetonide Intravitreal Implant) 0.59 Mg
-
-
-
92
-
-
54049091605
-
Iluvien-: A new sustained delivery technology for posterior eye disease
-
Kane FE, Burdan J, Cutino A, Green KE. Iluvien-: A new sustained delivery technology for posterior eye disease. Expert Opin Drug Deliv 2008;5:1039-46
-
(2008)
Expert Opin Drug Deliv
, vol.5
, pp. 1039-1046
-
-
Kane, F.E.1
Burdan, J.2
Cutino, A.3
Green, K.E.4
-
93
-
-
33947275043
-
Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema
-
Kuppermann BD, Blumenkranz MS, Haller JA, et al. Randomized controlled study of an intravitreous dexamethasone drug delivery system in patients with persistent macular edema. Arch Ophthalmol 2007;125:309-17
-
(2007)
Arch Ophthalmol
, vol.125
, pp. 309-317
-
-
Kuppermann, B.D.1
Blumenkranz, M.S.2
Haller, J.A.3
-
96
-
-
78649910389
-
Role of thermo-responsiveness and poly(ethylene glycol) diacrylate cross-link density on protein release from poly(Nisopropylacrylamide) hydrogels
-
Drapala PW, Brey EM, Mieler WF, et al. Role of thermo-responsiveness and poly(ethylene glycol) diacrylate cross-link density on protein release from poly(Nisopropylacrylamide) hydrogels. J Biomater Sci Polym Ed 2011;22:59-75
-
(2011)
J Biomater Sci Polym Ed
, vol.22
, pp. 59-75
-
-
Drapala, P.W.1
Brey, E.M.2
Mieler, W.F.3
-
97
-
-
79952107113
-
The effects of cross-linked thermoresponsive PNIPAAm-based hydrogel injection on retinal function
-
Turturro SB, Guthrie MJ, Appel AA. The effects of cross-linked thermoresponsive PNIPAAm-based hydrogel injection on retinal function. Biomaterials 2011;32:3620-6
-
(2011)
Biomaterials
, vol.32
, pp. 3620-3626
-
-
Turturro, S.B.1
Guthrie, M.J.2
Appel, A.A.3
-
98
-
-
84895466689
-
The effect of glutathione as chain transfer agent in PNIPAAm-based thermo-responsive hydrogels for controlled release of proteins
-
Drapala PW, Jiang B, Chiu YC, et al. The effect of glutathione as chain transfer agent in PNIPAAm-based thermo-responsive hydrogels for controlled release of proteins. Pharm Res 2014;31:742-53
-
(2014)
Pharm Res
, vol.31
, pp. 742-753
-
-
Drapala, P.W.1
Jiang, B.2
Chiu, Y.C.3
-
99
-
-
84892365869
-
Objective area measurement technique for choroidal neovascularization
-
Guthrie MJ, Osswald CR, Valio NL, et al. Objective area measurement technique for choroidal neovascularization. Microvasc Res 2014;91:1-7
-
(2014)
Microvasc Res
, vol.91
, pp. 1-7
-
-
Guthrie, M.J.1
Osswald, C.R.2
Valio, N.L.3
|