Reduction of diabetic macular edema by oral administration of the kinase inhibitor PKC412

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 3, 2004, Pages 922-931

  Campochiaro, Peter A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MIDOSTAURIN; PHOSPHOTRANSFERASE INHIBITOR; PLACEBO; DRUG DERIVATIVE; PROTEIN KINASE C; STAUROSPORINE;

ABDOMINAL PAIN; ADULT; AGED; ANEMIA; ARTICLE; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC MACULAR EDEMA; DIARRHEA; DIZZINESS; DOSE CALCULATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; DRUG TOLERABILITY; EYE PHOTOGRAPHY; FEMALE; FLUORESCENCE ANGIOGRAPHY; FUNDUS PHOTOGRAPHY; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; HYPERGLYCEMIA; INCREASED LACRIMATION; LACRIMATION; LEUKOPENIA; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RETINA FOVEA; RETINA MACULA EDEMA; RETINA THICKENING; RETINA VOLUME; THICKNESS; URTICARIA; VISUAL ACUITY; VISUAL IMPAIRMENT; VOLUMETRY; VOMITING; DIABETIC RETINOPATHY; DRUG ANTAGONISM; DRUG EFFECT; MIDDLE AGED; ORAL DRUG ADMINISTRATION; PATHOLOGY; RETINA; RETINA MACULA CYSTOID EDEMA; SAFETY;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; DIABETIC RETINOPATHY; DOUBLE-BLIND METHOD; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; MACULAR EDEMA, CYSTOID; MALE; MIDDLE AGED; PROTEIN KINASE C; RETINA; SAFETY; STAUROSPORINE; TOMOGRAPHY, OPTICAL COHERENCE; VISUAL ACUITY;

EID: 1542742166     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0955     Document Type: Article

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