Periocular Injection of Microspheres Containing PKC412 Inhibits Choroidal Neovascularization in a Porcine Model

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 11, 2003, Pages 4989-4993

  Saishin, Yoshitsugu ^a   Silva, Raquel Lima ^a   Saishin, Yumiko ^a   Callahan, Kevin ^a   Schoch, Christian ^b   Ahlheim, Markus ^b   Lai, Hong ^a   Kane, Frances ^c   Brazzell, R K ^c   Bodmer, David ^b   Campochiaro, Peter A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

^c Novartis Ophthalmics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSPHERE; MIDOSTAURIN; PLATELET DERIVED GROWTH FACTOR; POLYGLACTIN; PROTEIN KINASE C INHIBITOR; STEM CELL FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRUCH MEMBRANE; CHOROID; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; FEMALE; IMAGE ANALYSIS; LASER COAGULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RETINA; SUBRETINAL NEOVASCULARIZATION; SWINE; TECHNIQUE; TIME SERIES ANALYSIS; VITREOUS BODY;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOLOGICAL AVAILABILITY; BRUCH MEMBRANE; CHOROID; CHOROIDAL NEOVASCULARIZATION; DISEASE MODELS, ANIMAL; DRUG CARRIERS; FEMALE; INJECTIONS; LACTIC ACID; LASER COAGULATION; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; PROTEIN KINASE C; RETINA; STAUROSPORINE; SWINE; VITREOUS BODY;

EID: 0142231905     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0600     Document Type: Article

References (22)

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