Evaluation of gellan gum fluid gels as modified release oral liquids

International Journal of Pharmaceutics

Volumn 475, Issue 1, 2014, Pages 335-343

  Mahdi, Mohammed H ^a   Conway, Barbara R ^a   Smith, Alan M ^a  

^a UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

Gel; Gellan gum; Modified release; Oral liquid; Paediatric; Polysaccharides

Indexed keywords

BIOPOLYMER; GELLAN; IBUPROFEN; NANOMATERIAL; BACTERIAL POLYSACCHARIDE; GEL;

ACIDITY; ARTICLE; DRUG RELEASE; DRUG SOLUBILITY; DRUG SYNTHESIS; DYSPHAGIA; GEL; GELATION; GELLAN GUM FLUID GEL; MICROSCOPY; PH; SHEAR RATE; STOMACH JUICE; VISCOELASTICITY; VISCOMETRY; CHEMISTRY; MEDICINAL CHEMISTRY; ORAL DRUG ADMINISTRATION; PROCEDURES;

ADMINISTRATION, ORAL; CHEMISTRY, PHARMACEUTICAL; GELS; HYDROGEN-ION CONCENTRATION; IBUPROFEN; POLYSACCHARIDES, BACTERIAL;

EID: 84907199445     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.08.044     Document Type: Article

References (38)

1. R.J. Babu, S. Sathigari, M.T. Kumar, and J.K. Pandit Formulation of controlled release gellan gum macro beads of amoxicillin Current Drug Deliv. 7 2010 36 43
2. H.K. Batchelor, R. Kendall, S. Desset-Brethes, R. Alex, and T.B. Ernest Application of in vitro biopharmaceutical methods in development of immediate release oral dosage forms intended for paediatric patients Eur. J. Pharm. Biopharm. 85 2013 833 842
3. A. Bowles, J. Keane, T. Ernest, D. Clapham, and C. Tuleu Specific aspects of gastrointestinal transit in children for drug delivery design Int. J. Pharm. 395 2010 37 43
4. J.F. Bradbeer, R. Hancocks, F. Spyropoulos, and I.T. Norton Self-structuring foods based on acid-sensitive low and high acyl mixed gellan systems to impact on satiety Food Hydrocolloid 35 2014 522 530
5. J. Carlfors, K. Edsman, R. Petersson, and K. Jörnving Rheological evaluation of Gelrite® in situ gels for ophthalmic use Eur. J. Pharm. Sci. 6 1998 113 119
6. R. Chandrasekaran, L.C. Puigjaner, K.L. Joyce, and S. Arnott Cation interactions in gellan: an-X-ray study of the potassium salt Carbohydr. Res. 181 1988 23 40
7. M. Cuña, J.L. Vila Jato, and D. Torres Controlled-release liquid suspensions based on ion-exchange particles entrapped within acrylic microcapsules Int. J. Pharm. 199 2000 151 158
8. L. Dai, X.X. Liu, Y.L. Liu, and Z. Tong Concentration dependence of critical exponents for gelation in gellan gum aqueous solutions upon cooling Eur. Polym. J. 44 2008 4012 4019
9. A. Dalmoro, G. Lamberti, G. Titomanlio, A.A. Barba, and M. d'Amore Enteric micro-particles for targeted oral drug delivery AAPS PharmsciTech 11 2010 1500 1507
10. P.B. Deasy, and K.J. Quigley Rheological evaluation of deacetylated gellan gum (Gelrite®) for pharmaceutical use Int. J. Pharm. 73 1991 117 123
11. W. de Carvalho, and M. Djabourov Physical gelation under shear for gelatin gels Rheol. Acta 36 1997 591 609
12. L.W. Doner Rapid purification of commercial gellan gum to highly soluble and gellable monovalent cation salts Carbohydr. Polym. 32 1997 245 247
13. I. Fernández Farrés, and I.T. Norton Formation kinetics and rheology of alginate fluid gels produced by in-situ calcium release Food Hydrocolloid 40 2014 76 84
14. A. Gabriele, F. Spyropoulos, and I.T. Norton Kinetic study of fluid gel formation and viscoelastic response with kappa-carrageenan Food Hydrocolloid 23 2009 2054 2061
15. D.A. Garrec, B. Guthrie, and I.T. Norton Kappa carrageenan fluid gel material properties. Part 1: rheology Food Hydrocolloid 33 2013 151 159
16. D.A. Garrec, and I.T. Norton Understanding fluid gel formation and properties J. Food Eng. 112 2012 175 182
17. H. Grasdalen, and O. Smidsrod Gelation of gellan gum Carbohydr. Polym. 7 1987 371 393
18. K. Itoh, R. Tsuruya, T. Shimoyama, H. Watanabe, S. Miyazaki, A.D. Emanuele, and D. Attwood In situ gelling xyloglucan/alginate liquid formulation for oral sustained drug delivery to dysphagic patients Drug Dev. Ind. Pharm. 36 2010 449 455
19. K. Itoh, M. Yahaba, A. Takahashi, R. Tsuruya, S. Miyazaki, M. Dairaku, M. Togashi, R. Mikami, and D. Attwood In situ gelling xyloglucan/pectin formulations for oral sustained drug delivery Int. J. Pharm. 356 2008 95 101
20. S.H. Jahromi, L.M. Grover, J.Z. Paxton, and A.M. Smith Degradation of polysaccharide hydrogels seeded with bone marrow stromal cells J. Mech. Behav. Biomed. Mater. 4 2011 1157 1166
21. W. Kubo, K. Itoh, S. Miyazaki, and D. Attwood Oral sustained delivery of theophylline and cimetidine from in situ gelling pectin formulations in rabbits Drug Dev. Ind. Pharm. 31 2005 819 825
22. W. Kubo, Y. Konno, S. Miyazaki, and D. Attwood In situ gelling pectin formulations for oral sustained delivery of paracetamol Drug Dev. Ind. Pharm. 30 2004 593 599
23. W. Kubo, S. Miyazaki, and D. Attwood Oral sustained delivery of paracetamol from in situ-gelling gellan and sodium alginate formulations Int. J. Pharm. 258 2003 55 64
24. S. Miyazaki, H. Aoyama, N. Kawasaki, W. Kubo, and D. Attwood In situ-gelling gellan formulations as vehicles for oral drug delivery J. Control. Release 60 1999 287 295
25. S. Miyazaki, K. Endo, N. Kawasaki, W. Kubo, H. Watanabe, and D. Attwood Oral sustained delivery of paracetamol from in situ gelling xyloglucan formulations Drug Dev. Ind. Pharm. 29 2003 113 119
26. S. Miyazaki, W. Kubo, K. Itoh, Y. Konno, M. Fujiwara, M. Dairaku, M. Togashi, R. Mikami, and D. Attwood The effect of taste masking agents on in situ gelling pectin formulations for oral sustained delivery of paracetamol and ambroxol Int. J. Pharm. 297 2005 38 49
27. E.R. Morris, K. Nishinari, and M. Rinaudo Gelation of gellan - a review Food Hydrocolloid 28 2012 373 414
28. A. Nagita, K. Amemoto, A. Yoden, S. Aoki, M. Sakaguchi, K. Ashida, and M. Mino Diurnal variation in intragastric pH in children with and without peptic ulcers Pediatr. Res. 40 1996 528 532
29. Norton, I.T., Foster, T., Brown, R., 1998. The science and technology of fluid gels. In: Williams, P.A., Phillips, G.O. (Eds.), Gums and Stabilisers for the Food Industry, 9, 259-269.
30. I.T. Norton, D.M. Goodall, S.A. Frangou, E.R. Morris, and D.A. Rees Mechanism and dynamics of conformational ordering in xanthan polysaccharides J. Mol. Biol. 175 1984 371 394
31. I.T. Norton, D.A. Jarvis, and T.J. Foster A molecular model for the formation and properties of fluid gels Int. J. Biol. Macromol. 26 1999 255 261
32. E. Ogawa Conformational transition of polysaccharide sodium-gellan gum in aqueous solutions Macromolecules 29 1996 5178 5182
33. J.T. Oliveira, L. Martins, R. Picciochi, P.B. Malafaya, R.A. Sousa, N.M. Neves, J.F. Mano, and R.L. Reis Gellan gum: a new biomaterial for cartilage tissue engineering applications J. Biomed. Mater. Res. 93 2010 852 863
34. P.S. Rajinikanth, and B. Mishra Floating in situ gelling system for stomach site-specific delivery of clarithromycin to eradicate H. pylori J. Control. Release 125 2008 33 41
35. D.A. Rees, E.R. Morris, D. Thom, and J. Madden Shapes and interactions of carbohydrate chains G.O. Aspinall, The Polysaccharides Vol. 1 1982 Academic press New York 195-290
36. A.M. Smith, A. Ingham, L.M. Grover, and Y. Perrie Polymer film formulations for the preparation of enteric pharmaceutical capsules J. Pharm. Pharmacol. 62 2010 167 172
37. A.M. Smith, R.M. Shelton, Y. Perrie, and J.J. Harris An initial evaluation of gellan gum as a material for tissue engineering applications J. Biomater. App. 22 2007 241 254
38. G. Sworn, G.R. Sanderson, and W. Gibson Gellan gum fluid gels Food Hydrocolloid 9 1995 265 271