Role of polymeric biomaterials as wound healing agents

International Journal of Lower Extremity Wounds

Volumn 13, Issue 3, 2014, Pages 180-190

  Agrawal, Priyanka ^a   Soni, Sandeep ^a   Mittal, Gaurav ^a   Bhatnagar, Aseem ^a  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

polymer; wound dressing; wound healing

Indexed keywords

ABSORBENT; AGAR; ALGINIC ACID; ANTIINFECTIVE AGENT; ARABINOGALACTAN; BIOMATERIAL; BIOPOLYMER; CALCIUM ALGINATE; CELLULOSE; CHITIN; CHITOSAN; COLLAGEN; DEXTRAN; FIBRIN; FIBRINOGEN; FIBRONECTIN; GELATIN; HYALURONIC ACID; POLYACRYLIC ACID; POLYCAPROLACTONE; POLYGLACTIN; POLYGLYCOLIC ACID; POLYLACTIC ACID; POLYPROPYLENE; STARCH; THROMBIN; POLYMER;

ANGIOGENESIS; ANTIMICROBIAL ACTIVITY; APOPTOSIS; BACTERIAL SKIN DISEASE; BIOCOMPATIBILITY; BIODEGRADABILITY; BLOOD CLOTTING; CELL ADHESION; COLLAGEN SYNTHESIS; EPITHELIZATION; EXTRACELLULAR MATRIX; GRANULATION TISSUE; HYDROPHILICITY; INFLAMMATION; LYMPH VESSEL; PERSISTENT INFECTION; REVIEW; SKIN FIBROBLAST; SMOOTH MUSCLE FIBER; THROMBOCYTE ACTIVATION; TISSUE REGENERATION; VASOCONSTRICTION; WOUND CONTRACTION; WOUND DRESSING; WOUND HEALING; WOUND HEALING IMPAIRMENT; WOUND INFECTION; BANDAGE; HUMAN;

BANDAGES; BIOCOMPATIBLE MATERIALS; HUMANS; POLYMERS; WOUND HEALING;

EID: 84907196998     PISSN: 15347346     EISSN: 15526941     Source Type: Journal    
DOI: 10.1177/1534734614544523     Document Type: Review

References (123)

1. Lazarus GS, Cooper DM, Knighton DR, et al. Definitions and guidelines for assessment of wounds and evaluation of healing. Arch Dermatol. 1994 ; 130: 489-493
2. Percival JN. Classification of wounds and their management. Surgery. 2002 ; 20: 114-117
3. Harding KG, Morris HL, Patel GK. Science, medicine and the future: healing chronic wounds. BMJ. 2002 ; 324: 160-163
4. Moore K, McCallion R, Searle RJ, Stacey MC, Harding KG. Prediction and monitoring the therapeutic response of chronic dermal wounds. Int Wound J. 2006 ; 3: 89-96
5. Cutting K, White RJ. Maceration of the skin and wound bed 1: its nature and causes. J Wound Care. 2002 ; 11: 275-278
6. Bolton L, Rijswijk VL. Wound dressings: meeting clinical and biological needs. Dermatol Nurs. 1991 ; 3: 146-161
7. Krasner D, Kennedy KL, Rolstad BS, Roma AW. The ABCs of wound care dressings. Wound Manage. 1993 ; 66: 68-69
8. Eccleston GM Pharmaceutics: The Science of Dosage Form Design. 3 rd ed.London, UK: Churchill Livingstone; 2007:264-271. Aulton ME, ed. London, UK: Churchill Livingstone ; 2007: 264-271.
9. Rothe M, Falanga V. Growth factors, their biology and promise in dermatologic disease and tissue repair. Arch Dermatol. 1989 ; 125: 1390-1398
10. Shakespeare P. Burn wound healing and skin substitutes. Burns. 2001 ; 27: 517-522
11. Schultz GS Acute and Chronic Wounds: Nursing Management. 2 nd ed.St Louis, MO: Mosby; 1999:413-429. Bryant RA Nix DP, ed. St Louis, MO: Mosby ; 1999: 413-429.
12. Martin P. Wound healing: aiming for perfect skin regeneration. Science. 1997 ; 276: 75-81
13. Lawrence WT. Physiology of the acute wound. Clin Plast Surg. 1998 ; 25 (3). 321-40
14. Yamaguchi Y, Yoshikawa Y. Cutaneous wound healing: an update. J Dermatol. 2001 ; 28: 521-534
15. Singer AJ, Clark RA. Mechanisms of disease: cutaneous wound healing. N Engl J Med. 1999 ; 341: 738-746
16. Bolton L, van Rijswijk L. Wound dressings: meeting clinical and biological needs. Dermatol Nurs. 1991 ; 3: 146-161
17. Kokabi M, Sirousazar M, Hassan ZM. PVA-clay-nanocomposite hydrogels for wound dressing. Eur Polym J. 2007 ; 43: 773-781
18. Watson NFS, Hodgkin W. Wound dressings. Surgery. 2005 ; 23: 52-55
19. Capturing the full power of biomaterials for military medicine. http://www.nap.edu/catalog.php?record-id=11063. Accessed July 9, 2014.
20. Robinson K. Controlling bleeding in the field: hemostatic powders and dressings debut in the prehospital setting. J Emerg Nurs. 2004 ; 30: 160-161
21. Neuffer MC, McDivitt J, Rose D, et al. Hemostatic dressings for the first responder: a review. Mil Med. 2004 ; 169: 716-720
22. Seyednejad H, Imani M, Jamieson T, Seifalian AM. Topical haemostatic agents. Br J Surg. 2008 ; 95: 1197-1225
23. Stewart R, Myers J, Dent D, et al. Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention. J Trauma. 2003 ; 54: 66-71
24. Champion H, Bellamy R, Roberts C, Leppaniemi A. A profile of combat injury. J Trauma. 2003 ; 54: 13-19
25. Pusateri AE, Holcomb JB, Kheirabadi BS, Alam HB, Wade CE, Ryan KL. Making sense of the preclinical literature on advanced hemostatic products. J Trauma. 2006 ; 60: 674-682
26. Torchiana DF. Polyethylene glycol based synthetic sealants: potential uses in cardiac surgery. J Card Surg. 2003 ; 18: 504-506
27. Reece TB, Maxey TS, Kron IL. A prospectus on tissue adhesives. Am J Surg. 2001 ; 182: 40-44
28. Bishoff JT, Cornum RL, Perahia B, et al. Laparoscopic hemi nephrectomy using a new fibrin sealant powder. Urology. 2003 ; 62: 1139-1143
29. Kilbourne M, Keledjian K, Hess JR, Scalea T, Bochicchio GV. Hemostatic efficacy of modified amylopectin powder in a lethal porcine model of extremity arterial injury. Ann Emerg Med. 2009 ; 53: 804-810
30. Oz MC, Rondinone JF, Shargill NS. Floseal matrix: new generation topical hemostatic sealant. J Card Surg. 2003 ; 18: 486-493
31. Kim BS, Baez CE, Atala A. Biomaterials for tissue engineering. World J Urol. 2000 ; 18: 2-9
32. Gomes ME, Ribeiro AS, Malafaya PB, Reis RL, Cunha AM. A new approach based on injection molding to produce biodegradable starch-based polymeric scaffolds: morphology, mechanical and degradation behavior. Biomaterials. 2001 ; 22: 883-889
33. Gomes ME, Reis RL, Behravesh E, Mikos AG, Sikavitsas VI. Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A. 2003 ; 67: 87-95
34. Salgado AJ, Coutinho OP, Reis RL. Novel starch-based scaffolds for bone tissue engineering: cytotoxicity, cell culture, and protein expression. Tissue Eng. 2004 ; 10: 465-474
35. Rodriguez-Gonzalez FJ, Ramsay BA, Favis BD. Rheological and thermal properties of thermoplastic starch with high glycerol content. Carbohydr Polym. 2004 ; 58: 139-147
36. Ciardelli G, Chiono V, Vozzi G, et al. Blends of poly-(caprolactone) and polysaccharides in tissue engineering applications. Biomacromolecules. 2005 ; 6: 1961-1976
37. Azevedo HS, Gama FM, Reis RL. In vitro assessment of the enzymatic degradation of several starch based biomaterials. Biomacromolecules. 2003 ; 4: 1703-1712
38. Entcheva E, Bien H, Yin LH, et al. Functional cardiac cell constructs on cellulose-based scaffolding. Biomaterials. 2004 ; 25: 5753-5762
39. Svensson A, Nicklasson E, Harrah T, et al. Bacterial cellulose as a potential scaffold for tissue engineering of cartilage. Biomaterials. 2005 ; 26: 419-431
40. Franz G, Blaschek W Methods in Plant Biochemistry. Dey PM, ed. London, UK: Academic Press ; 1990: 291-322.
41. Stephen AM, Churms SC, Vogt DC. Exudate gums in methods in plant biochemistry. Carbohydrates. 1990 ; 2: 483-522
42. Bouhadir KH, Lee KY, Alsberg E, et al. Degradation of partially oxidized alginate and its potential application for tissue engineering. Biotechnol Prog. 2001 ; 17: 945-950
43. Percival E, McDowell RH. Algal polysaccharides: methods in plant biochemistry. Carbohydrates. 1990 ; 2: 523-547
44. Awad HA, Wickham MQ, Leddy HA, Gimble JM, Guilak F. Chondrogenic differentiation of adipose derived adult stem cells in agarose, alginate, and gelatin scaffolds. Biomaterials. 2004 ; 25: 3211-3222
45. Balgude AP, Yu X, Szymanski A, Bellamkonda RV. Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials. 2001 ; 22: 1077-1084
46. Mauck RL, Wang CCB, Oswald ES, Ateshian GA, Hung CT. The role of cell seeding density and nutrient supply for articular cartilage tissue engineering with deformational loading. Osteoarthritis Cartilage. 2003 ; 11: 879-890
47. Kim SK, Rajapakse N. Enzymatic production and biological activities of chitosan oligosaccharides (COS): a review. Carbohydr Polym. 2005 ; 62: 357-368
48. Nettles DL, Elder SH, Gilbert JA. Potential use of chitosan as a cell scaffold material for cartilage tissue engineering. Tissue Eng. 2002 ; 8: 1009-1016
49. Freier T, Montenegro R, Koh H, Shoichet MS. Chitin-based tubes for tissue engineering in the nervous system. Biomaterials. 2005 ; 26: 4624-4632
50. Levesque SG, Lim RM, Shoichet MS. Macroporous interconnected dextran scaffolds of controlled porosity for tissue-engineering applications. Biomaterials. 2005 ; 26: 7436-7446
51. Cascone MG, Barbani N, Cristallini C, et al. Bioartificial polymeric materials based on polysaccharides. J Biomater Sci Polym. 2001 ; 12: 267-281
52. Englehart MS, Cho SD, Tieu BH, et al. A novel highly porous silica and chitosan-based hemostatic dressing is superior to hemcon and gauze sponges. J Trauma. 2008 ; 65: 884-892
53. Sambasivan CN, Cho SD, Zink KA, Differding JA, Schreiber MA. A highly porous silica and chitosan-based hemostatic dressing is superior in controlling hemorrhage in a severe groin injury model in swine. Am J Surg. 2009 ; 197: 576-580
54. Jiang L, Yan W, Li J, et al. Addition of an alginate to a modified zeolite improves hemostatic performance in a swine model of lethal groin injury. J Trauma. 2009 ; 66: 612-620
55. Carrawaya JW, Kenta D, Younga K, Colea A, Friedmanb R, Ward KR. Comparison of a new mineral based hemostatic agent to a commercially available granular zeolite agent for hemostasis in a swine model of lethal extremity arterial hemorrhage. Resuscitation. 2008 ; 78: 230-235
56. Muehrcke DD, Barberi P, Shimp WM. Calcium phosphate cements to control bleeding in osteoporotic sternums. Ann Thorac Surg. 2007 ; 84: 259-261
57. Momota Y, Miyamoto Y, Ishikawa K, et al. Effects of neutral sodium hydrogen phosphate on the setting property and hemostatic ability of hydroxyapatite putty as a local hemostatic agent for bone. J Biomed Mater Res B Appl Biomater. 2004 ; 69: 99-103
58. Wallace DG, Cruise GM, Rhee WM, et al. A tissue sealant based on reactive multifunctional polyethylene glycol. J Biomed Mater Res. 2001 ; 58: 545-555
59. Otani Y, Tabata Y, Ikada Y. Hemostatic capability of rapidly curable glues from gelatin, poly (l-glutamic acid), and carbodi imide. Biomaterials. 1998 ; 19: 2091-2098
60. Whang HS, Kirsch W, Zhu YH, Yang CZ, Hudson SM. Hemostatic agents derived from chitin and chitosan. J Macromol Sci Part C Polym Rev. 2005 ; 45: 309-323
61. Peter MG. Applications and environmental aspects of chitin and chitosan. Pure Appl Chem. 1995 ; 32: 629-640
62. Rinaudo M, Pavlov G, Desbrières J. Influence of acetic acid concentration on the solubilization of chitosan. Polymer. 1999 ; 40: 7029-7032
63. Okamoto Y, Yano R, Miyatake K, Tomohiro I, Shigemasa Y, Minami S. Effects of chitin and chitosan on blood coagulation. Carbohydr Polym. 2003 ; 53: 337-342
64. Oliver LC, Blaine G. Haemostasis with absorbable alginates in neurosurgical practice. Br J Surg. 1950 ; 37: 307-310
65. Ueno H, Mori T, Fujinaga T. Topical formulations and wound healing applications of chitosan. Adv Drug Deliv Rev. 2001 ; 52: 105-115
66. Chou TC, Fu E, Wu CJ, Yeh JH. Chitosan enhances platelet adhesion and aggregation. Biochem Biophys Res Commun. 2003 ; 302: 480-483
67. Loke WK, Lau SK, Yong LL, Khor E, Sum CK. Wound dressing with sustained anti-microbial capability. J Biomed Mater Res. 2000 ; 53: 8-17
68. Peh K, Khan T, Ch'ng H. Mechanical, bioadhesive strength and biological evaluations of chitosan films for wound dressing. J Pharm Pharm Sci. 2000 ; 3: 303-311
69. Paul W, Sharma C. Chitosan and alginate wound dressings: a short review. Trends Biomater Artif Organs. 2004 ; 18: 18-23
70. Farndale RW, Sixma JJ, Barnes MJ, De Groot PG. The role of collagen in thrombosis and hemostasis. J Thromb Hemostasis. 2004 ; 2: 561-573
71. Schiele U, Kuntz G, Riegler A. Haemotyptic preparations on the basis of collagen alone and as fixed combination with fibrin glue. Clin Mater. 1992 ; 9: 169-177
72. Silverstein ME, Keown K, Owen JA, Chvapil M. Collagen fibers as a fleece hemostatic agent. J Trauma. 1980 ; 20: 688-694
73. Green JG, Durham TM. Application of instat hemostat in the control of gingival hemorrhage in the patient with thrombocytopenia: a case report. Oral Surg Oral Med Oral Pathol. 1991 ; 71: 27-30
74. Wagner WR, Pachence JM, Ristich J, Johnson PC. Comparative in-vitro analysis of topical hemostatic agents. J Surg Res. 1996 ; 66: 100-108
75. Zwischenberger JB, Brunston RL, Swann JR, Conti VR. Comparison of two topical collagen- based hemostatic sponges during cardiothoracic procedures. J Invest Surg. 1999 ; 12: 101-106
76. Maddalo F, Lampietra M, Eldridge S, Torgerson R. Collagen hemostatic foam.. 2000 ;:
77. Yang C, Hillas P, Tang J, Balan J, Notbohm H, Polarek J. Development of a recombinant human collagen-type iii based hemostat. J Biomed Mater Res B Appl Biomater. 2004 ; 69: 18-24
78. Doita M, Nishida K, Kurosaka M. Radiculopathy due to microfibrillar collagen hemostat mimicking recurrence of disc herniation. Skeletal Radiol. 2006 ; 35: 953-955
79. Sirlak M, Eryilmaz S, Yazicioglu L, et al. Comparative study of micro-fibrillar collagen hemostat (colgel) and oxidized cellulose (SURGICEL) in high transfusion-risk cardiac surgery. J Thorac Cardiovasc Surg. 2003 ; 126: 666-670
80. Eastoe JE, Leach AA The Science and Technology of Gelatin. Ward A Courts A, ed. London, UK: Academic Press ; 1977: 77-90.
81. Permpongkosol S, Nicol TL, Bagga HS, Kohanim S., Kavoussi L, Solomon SB. Prophylactic gelatin sponge tract injection to prevent bleeding after percutaneous renal cryo-ablation in a swine model. J Vasc Interv Radiol. 2006 ; 17: 1505-1509
82. Singh I, Saran RN, Jain M. Does sealing of the tract with absorbable gelatin (spongostanò) facilitate tubeless pcnl? A prospective study. J Endourol. 2008 ; 22: 2485-2493
83. Griffith BC, Morey AF, Rozanski TA, et al. Central renal stab wounds: treatment with augmented fibrin sealant in a porcine model. J Urol. 2004 ; 171: 445-447
84. Liening DA, Lundy L, Silberberg B, Finstuen K. A comparison of the biocompatibility of three absorbable hemostatic agents in the rat middle ear. Otolaryngol Head Neck Surg. 1997 ; 116: 454-457
85. Sabel M, Stummer W. The use of local agents: SURGICEL and SURGIFOAM. Eur Spine J. 2004 ; 13: 97-101
86. Dhandayuthapani B, Krishnan UM, Sethuraman S. Fabrication and characterization of chitosan-gelatin blend nanofibers for skin tissue engineering. J Biomed Mater Res B Appl Biomater. 2010 ; 94: 264-272
87. Solchaga LA, Dennis JE, Goldberg VM, Caplan AI. Hyaluronic acid-based polymers as cell carriers for tissue-engineered repair of bone and cartilage. J Orthop Res. 1999 ; 17: 205-213
88. Stillaert FB, Di Bartolo C, Hunt JA, et al. Human clinical experience with adipose precursor cells seeded on hyaluronic acid-based spongy scaffolds. Biomaterials. 2008 ; 29: 3953-3959
89. West DC, Kumar S. Endothelial cell proliferation and diabetic retinopathy. Lancet. 1988 ; 1: 715-716
90. West DC, Hampson IN, Arnold F, Kumar S. Angiogenesis induced by degradation products of hyaluronic acid. Science. 1985 ; 228: 1324-1326
91. Perng CK, Wang YJ, Tsi CH, Ma H. In vivo angiogenesis effect of porous collagen scaffold with hyaluronic acid oligosaccharides. J Surg Res. 2011 ; 168: 9-15
92. Slevin M, Krupinski J, Gaffney J, et al. Hyaluronan-mediated angiogenesis in vascular disease: uncovering RHAMM and CD44 receptor signaling pathways. Matrix Biol. 2007 ; 26: 58-68
93. Ågren MS. Four alginate dressings in the treatment of partial thickness wounds: a comparative experimental study. Br J Plast Surg. 1996 ; 49: 129-134
94. Blaine G. Experimental observations on absorbable alginate products in surgery. Ann Surg. 1947 ; 125: 102-107
95. Matthew IR, Browne RM, Frame JW, Millar BG. Alginate fiber dressing for oral mucosal wounds. Oral Surg Oral Med Oral Pathol. 1994 ; 77: 456-460
96. Matthew IR, Browne RM, Frame JW, Millar BG. Tissue response to a haemostatic alginate wound dressing in tooth extraction sockets. Br J Oral Maxillofac Surg. 1993 ; 31: 165-169
97. Segal HC, Hunt BJ, Gilding K. The effects of alginate and non-alginate wound dressings on blood coagulation and platelet activation. J Biomater Appl. 1998 ; 12: 249-257
98. Paul W, Sharma CP Encyclopedia of Surface and Colloid Science. Somasundaram P, ed. New York, NY: Marcel Dekker ; 2004: 5056-5067.
99. Seymour J. Alginate dressing in wound care management. Nurs Times. 1997 ; 93: 49-52
100. Sedlarik KM, Nusser B. Modern wound dressings. 1: Alginates [in German]. Z Arztl Fortbild (Jena). 1992 ; 86: 559-63
101. Piacquadio D, Nelson DB. Alginates: a "new" dressing alternative. J Dermatol Surg Oncol. 1992 ; 18: 992-995
102. Developments in Wound Care. London, UK: PJB Publications ; 1994: 43-60.
103. O'Donoghue JM, O'Sullivan ST, Beausang ES, Panchal JI, O'Shaughnessy M, O'Connor TP. Calcium alginate dressings promote healing of split skin graft donor sites. Acta Chir Plast. 1997 ; 39: 53-55
104. Disa JJ, Alizadeh K, Smith JW, Hu Q, Cordeiro PG. Evaluation of a combined calcium sodium alginate and bio-occlusive membrane dressing in the management of split-thickness skin graft donor sites. Ann Plast Surg. 2001 ; 46: 405-408
105. Franklin B, Lowell S. Cellulose oxidation by a perfluorinated hydrocarbon solution of nitrogen dioxide.. 1993 ;:
106. Pendharkar S, Guo J. Biodegradable hemostatic wound dressings.. 2004 2004 ;:
107. Christenson LJ, Otley CC, Roenigk RK. Oxidized regenerated cellulose gauze for hemostasis of a two-stage interpolation flap pedicle. Dermatol Surg. 2004 ; 30: 1593-1594
108. Mair H, Kaczmarek I, Oberhoffer M, Groetzner J, Daebritz S, Reichart B. Surgical nu-knit hemostat for bleeding control of fragile sternum. J Thorac Cardiovasc Surg. 2005 ; 130: 605-606
109. Arat YO, Dorotheo EU, Tang RA, Boniuk M, Schiffman JS. Compressive optic neuropathy after use of oxidized regenerated cellulose in orbital surgery: review of complications, prophylaxis, and treatment. Ophthalmology. 2006 ; 113: 333-337
110. Laurence S, Bareille R, Baquey C, Fricain JC. Development of a resorbable macroporous cellulosic material used as hemostatic in an osseous environment. J Biomed Mater Res A. 2005 ; 73: 422-429
111. Blombäck B, Blombäck M. The molecular structure of fibrinogen. Ann N Y Acad Sci. 1972 ; 202: 77-97
112. Lundblad RL, Bradshaw RA, Gabriel D, Ortel TL, Lawson J, Mann KG. A review of the therapeutic uses of thrombin. Thromb Haemost. 2004 ; 91: 851-860
113. Blombäck B. Fibrinogen and fibrin-proteins with complex roles in hemostasis and thrombosis. Thromb Res. 1996 ; 83: 1-75
114. Budzinski A, Olexa S, Pandya B. Fibrin polymerization sites in fibrinogen and fibrin fragments. Ann NY Acad Sci. 1983 ; 202: 77-97
115. Folk JE, Finlayson JS. The epsilon-(gamma-glutamyl) lysine crosslink and the catalytic role of trans-glutaminases. Adv Protein Chem. 1977 ; 31: 1-133
116. Su CH, Sun CS, Juan SW, Hu CH, Ke WT, Sheu MT. Fungal mycelia as the source of chitin and polysaccharides and their applications as skin substitutes. Biomaterials. 1997 1169 ; 18 :
117. Muzzarelli RAA. Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone. Carbohydr Polym. 2009 ; 76: 167-182
118. Jayakumar R, Prabaharan M, Sudheesh Kumar PT, Nair SV, Tamura H. Biomaterials based on chitin and chitosan in wound dressing applications. Biotechnol Adv. 2011 ; 29: 322-337
119. Moustafa MG, Wittke R, Knittel D, Schollmeyer E. Use of chitosan/polyamine biopolymers based cotton as a model system to prepare antimicrobial wound dressing. Int J Diabetes Mellit. 2009 ; 1: 61-64
120. Kim YH, Sun G. Dye molecules as bridges for functional modification of nylon: antimicrobial functions. Textile Res J. 2000 ; 70: 728-733
121. Jixiong Y, Jiachong C. Antimicrobial yarn having nanosilver particles and methods for manufacturing the same.. 2003 ;:
122. Gulrajani ML. Nano finishes. Indian J Fibre Textile Res. 2006 ; 31: 187-201
123. Wallis TE Text Book of Pharmacognosy. New Delhi, India: CBS ; 2004 :