Mutations in the lamin B1 gene are not present in multiple sclerosis

European Journal of Neurology

Volumn 16, Issue 4, 2009, Pages 544-546

  Brussino, A ^a   D'Alfonso, S ^b   Cagnoli, C ^a   Di Gregorio, E ^a   Barberis, M ^a   Padovan, S ^a,c   Vaula, G ^a   Pinessi, L ^a   Squadrone, S ^d   Abete, M C ^d   Collimedaglia, L ^b   Guerini, F R ^e   Migone, N ^a   Brusco, A ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c CNR   (Italy)

^d LIGURIA E VALLE D AOSTA   (Italy)

^e IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

Lamin; LMNB1; Multiple sclerosis; Myelin

Indexed keywords

LAMIN B; LAMIN B1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE DUPLICATION; GENE SEQUENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NUCLEOTIDE SEQUENCE; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FAMILY; FEMALE; GENE DUPLICATION; HUMANS; LAMIN TYPE B; MALE; MULTIPLE SCLEROSIS; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 62849085779     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2009.02536.x     Document Type: Article

References (12)

1. Rizvi S. Multiple sclerosis: current and future treatment options. Endocrine, Metabolic & Immune Disorders Drug Targets 2007 7 : 292 299.
2. Zeis T, Schaeren-Wiemers N. Lame ducks or fierce creatures? The role of oligodendrocytes in multiple sclerosis Journal of Molecular Neuroscience 2008 35 : 91 100.
3. Miller DH, Leary SM. Primary-progressive multiple sclerosis. Lancet Neurology 2007 6 : 903 912.
4. Eldridge R, Anayiotos CP, Schlesinger S, et al. Hereditary adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. New England Journal of Medicine 1984 311 : 948 953.
5. Padiath QS, Saigoh K, Schiffmann R, et al. Lamin B1 duplications cause autosomal dominant leukodystrophy. Nature Genetics 2006 38 : 1114 1123.
6. Brussino A, Vaula G, Cagnoli C, et al. A novel family with lamin b1 duplication associated with adult-onset leukoencephalopathy. Journal of Neurology, Neurosurgery, and Psychiatry 2009 80 : 237 240.
7. Meijer IA, Simoes-Lopes AA, Laurent S, et al. A novel duplication confirms the involvement of 5q23.2 in autosomal dominant leukodystrophy. Archives of Neurology 2008 65 : 1496 1501.
8. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of Neurology 2001 50 : 121 127.
9. Lublin FD, Reingold SC. Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996 46 : 907 911.
10. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001 25 : 402 408.
11. Kenealy SJ, Babron MC, Bradford Y, et al. A second-generation genomic screen for multiple sclerosis. American Journal of Human Genetics 2004 75 : 1070 1078.
12. Broadley S, Sawcer S, D'Alfonso S, et al. A genome screen for multiple sclerosis in Italian families. Genes and Immunity 2001 2 : 205 210.