Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity

Journal of Biological Chemistry

Volumn 289, Issue 37, 2014, Pages 25737-25749

  Nguyen, Khanh Quynh N ^a   Tsou, Wen I ^a,b   Calarese, Daniel A ^d   Kimani, Stanley G ^a   Singh, Sukhwinder ^c   Hsieh, Shelly ^d   Liu, Yongzhang ^e   Lu, Bin ^e   Wu, Yi ^f   Garforth, Scott J ^d   Almo, Steve C ^d   Kotenko, Sergei V ^a,b,g   Birge, Raymond B ^a,g  

^a University of Medicine and Dentistry of New Jersey   (United States)

^b The State University of New Jersey   (United States)

^c UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e INSTITUTE OF BIOPHYSICS   (China)

^f SOOCHOW UNIVERSITY   (China)

^g New Jersey Medical School University Hospital Cancer Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; CYTOLOGY; DIGITAL STORAGE; DISEASES; ENZYMES; TISSUE CULTURE;

CANCER PROGRESSION; CELL TRANSFORMATION; EPITHELIAL CANCER CELLS; HUMAN BREAST CANCER CELLS; IMMUNE SUPPRESSION; PHOSPHATIDYLSERINE; RECEPTOR TYROSINE KINASE; STABLE EXPRESSION;

CELLS;

IMMUNOGLOBULIN; PHOSPHATIDYLSERINE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; PROTEIN MERTK; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; AXL RECEPTOR TYROSINE KINASE; MERTK PROTEIN, HUMAN; ONCOPROTEIN; TYRO3 PROTEIN, HUMAN;

AGAR MEDIUM; ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CANCER GROWTH; CANCER RESISTANCE; CELL MIGRATION; CELL MOTILITY; CELL TRANSFORMATION; CONTROLLED STUDY; EFFEROCYTOSIS; EPITHELIAL CANCER CELL LINE; FEMALE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN STRUCTURE; IMMUNOMODULATION; MEMBRANE BIOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLEIOTROPY; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR IMMUNITY; BREAST TUMOR; CELL MOTION; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHAGOCYTOSIS;

APOPTOSIS; BREAST NEOPLASMS; CELL MOVEMENT; CELL TRANSFORMATION, NEOPLASTIC; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PHAGOCYTOSIS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 84907164518     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.570838     Document Type: Article

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