Galectin-3 is a new MerTK-specific eat-me signal

Journal of Cellular Physiology

Volumn 227, Issue 2, 2012, Pages 401-407

  Caberoy, Nora B ^a   Alvarado, Gabriela ^a   Bigcas, Jo Lawrence ^a   Li, Wei ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GALECTIN 3;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHOSPHORYLATION; CELL ACTIVATION; CELL STIMULATION; CHROMATIN IMMUNOPRECIPITATION; CLONING; CONTROLLED STUDY; EPITHELIUM CELL; IMMUNOSURVEILLANCE; MACROPHAGE; MOUSE; NONHUMAN; OPEN READING FRAME; PHAGE DISPLAY; PHAGOCYTOSIS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; RECEPTOR AFFINITY;

ANIMALS; CELL LINE; CLONING, MOLECULAR; GALECTIN 3; GENE EXPRESSION REGULATION; HUMANS; MICE; PEPTIDE LIBRARY; PHAGOCYTOSIS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 82155179230     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22955     Document Type: Article

References (33)

1. Barile GR, Schmidt AM. 2007. RAGE and its ligands in retinal disease. Curr Mol Med 7: 758-765.
2. Bratkovic T. 2010. Progress in phage display: Evolution of the technique and its application. Cell Mol Life Sci 67: 749-767.
3. Caberoy NB, Zhou Y, Alvarado G, Fan X, Li W. 2009a. Efficient identification of phosphatidylserine-binding proteins by ORF phage display. Biochem Biophys Res Commun 386: 197-201.
4. Caberoy NB, Zhou Y, Li W. 2009b. Can phage display be used as a tool to functionally identify endogenous eat-me signals in phagocytosis? J Biomol Screen 14: 653-661.
5. Caberoy NB, Maiguel D, Kim Y, Li W. 2010a. Identification of tubby and tubby-like protein 1 as eat-me signals by phage display. Exp Cell Res 316: 245-257.
6. Caberoy NB, Zhou Y, Jiang X, Alvarado G, Li W. 2010b. Efficient identification of tubby-binding proteins by an improved system of T7 phage display. J Mol Recognit 23: 74-83.
7. Caberoy NB, Zhou Y, Li W. 2010c. Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis. EMBO J 29: 3898-3910.
8. Canesin G, Gonzalez-Peramato P, Palou J, Urrutia M, Cordon-Cardo C, Sanchez-Carbayo M. 2010. Galectin-3 expression is associated with bladder cancer progression and clinical outcome. Tumour Biol 31: 277-285.
9. Dumic J, Dabelic S, Flogel M. 2006. Galectin-3: An open-ended story. Biochim Biophys Acta 1760: 616-635.
10. Erwig LP, Henson PM. 2007. Immunological consequences of apoptotic cell phagocytosis. Am J Pathol 171: 2-8.
11. Fernandez GC, Ilarregui JM, Rubel CJ, Toscano MA, Gomez SA, Beigier Bompadre M, Isturiz MA, Rabinovich GA, Palermo MS. 2005. Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: Involvement of alternative MAPK pathways. Glycobiology 15: 519-527.
12. Grillo MA, Colombatto S. 2008. Advanced glycation end-products (AGEs): Involvement in aging and in neurodegenerative diseases. Amino Acids 35: 29-36.
13. Hafizi S, Dahlback B. 2006. Gas6 and protein S. Vitamin K-dependent ligands for the Axl receptor tyrosine kinase subfamily. FEBS J 273: 5231-5244.
14. Hsieh CL, Koike M, Spusta SC, Niemi EC, Yenari M, Nakamura MC, Seaman WE. 2009. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J Neurochem 109: 1144-1156.
15. Hughes RC. 1999. Secretion of the galectin family of mammalian carbohydrate-binding proteins. Biochim Biophys Acta 1473: 172-185.
16. Iacobini C, Oddi G, Menini S, Amadio L, Ricci C, Di Pippo C, Sorcini M, Pricci F, Pugliese F, Pugliese G. 2005. Development of age-dependent glomerular lesions in galectin-3/AGE-receptor-3 knockout mice. Am J Physiol Renal Physiol 289: F611-F621.
17. Kevany BM, Palczewski K. 2010. Phagocytosis of retinal rod and cone photoreceptors. Physiology 25: 8-15.
18. Kim Y, Caberoy NB, Alvarado G, Davis JL, Feuer WJ, Li W. 2011. Identification of Hnrph3 as an autoantigen for acute anterior uveitis. Clin Immunol 138: 60-66.
19. Krumpe LR, Atkinson AJ, Smythers GW, Kandel A, Schumacher KM, McMahon JB, Makowski L, Mori T. 2006. T7 lytic phage-displayed peptide libraries exhibit less sequence bias than M13 filamentous phage-displayed peptide libraries. Proteomics 6: 4210-4222.
20. Li W. 2011. Eat-me signals: Keys to molecular phagocyte biology and "appetite" control. J. Cell. Physiol. (in press)
21. Li W, Caberoy NB. 2010. New perspective for phage display as an efficient and versatile technology of functional proteomics. Appl Microbiol Biotechnol 85: 909-919.
22. Miksa M, Komura H, Wu R, Shah KG, Wang P. 2009. A novel method to determine the engulfment of apoptotic cells by macrophages using pHrodo succinimidyl ester. J Immunol Methods 342: 71-77.
23. Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K. 1996. Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem 271: 30022-30027.
24. Neumann H, Takahashi K. 2007. Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis. J Neuroimmunol 184: 92-99.
25. Paschke M. 2006. Phage display systems and their applications. Appl Microbiol Biotechnol 70: 2-11.
26. Ravichandran KS, Lorenz U. 2007. Engulfment of apoptotic cells: Signals for a good meal. Nat Rev Immunol 7: 964-974.
27. Rothlin CV, Lemke G. 2010. TAM receptor signaling and autoimmune disease. Curr Opin Immunol 22: 740-746.
28. Rotshenker S, Reichert F, Gitik M, Haklai R, Elad-Sfadia G, Kloog Y. 2008. Galectin-3/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI/II mediated myelin phagocytosis in microglia. Glia 56: 1607-1613.
29. Sano H, Hsu DK, Apgar JR, Yu L, Sharma BB, Kuwabara I, Izui S, Liu FT. 2003. Critical role of galectin-3 in phagocytosis by macrophages. J Clin Invest 112: 389-397.
30. Strick DJ, Vollrath D. 2010. Focus on molecules: MERTK. Exp Eye Res 91: 786-787.
31. Thorp E, Tabas I. 2009. Mechanisms and consequences of efferocytosis in advanced atherosclerosis. J Leukoc Biol 86: 1089-1095.
32. Uehara F, Ohba N, Ozawa M. 2001. Isolation and characterization of galectins in the mammalian retina. Invest Ophthalmol Vis Sci 42: 2164-2172.
33. Vlassara H, Li YM, Imani F, Wojciechowicz D, Yang Z, Liu FT, Cerami A. 1995. Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): A new member of the AGE-receptor complex. Mol Med 1: 634-646.