Allosteric inhibitors of calpains: Reevaluating inhibition by PD150606 and LSEAL

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 12, 2014, Pages 3367-3373

  Low, Kristin E ^a   Karunan Partha, Sarathy ^a   Davies, Peter L ^a,b   Campbell, Robert L ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Allosteric inhibitor Calcium activated protease Calpain Penta EF hand PD150606 Enzyme kinetics

Indexed keywords

CALPAIN 1; CALPAIN 2; CALPASTATIN; CASEIN; LSEAL PEPTIDE; PD 150606; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MECHANISM; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; IN VITRO STUDY; LIGHT SCATTERING; PROTEIN DEGRADATION; PROTEIN HYDROLYSIS; STEADY STATE;

EID: 84907148946     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.08.014     Document Type: Article

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