Crystal structure of calcium bound domain VI of calpain at 1.9 Å resolution and its role in enzyme assembly, regulation, and inhibitor binding

Nature Structural Biology

Volumn 4, Issue 7, 1997, Pages 539-547

  Lin, Guang Da ^a   Chattopadhyay, Debasish ^a   Maki, Masatoshi ^b   Wang, Kevin K W ^c   Carson, Mike ^a   Jin, Lei ^a   Yuen, Po Wai ^c   Takano, Emiko ^d   Hatanaka, Masakazu ^d   DeLucas, Lawrence J ^a   Narayana, Sthanam V L ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b NAGOYA UNIVERSITY   (Japan)

^c PFIZER INC   (United States)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4 IODOPHENYL) 2 MERCAPTO 2 PROPENOIC ACID; CALCIUM; CALCIUM BINDING PROTEIN; CALPAIN; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; SWINE;

ACRYLATES; AMINO ACID SEQUENCE; BINDING SITES; CALCIUM; CALPAIN; CRYSTALLOGRAPHY, X-RAY; CYSTEINE PROTEINASE INHIBITORS; DIMERIZATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; SEQUENCE HOMOLOGY, AMINO ACID;

SUIDAE; SUS SCROFA;

EID: 0030963932     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb0797-539     Document Type: Article

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