Synthesis and biological evaluation of (E)-1-(substituted)-3-phenylprop-2-en-1-ones bearing rhodanines as potent anti-microbial agents

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 29, Issue 5, 2014, Pages 647-653

  Song, Ming Xia ^a   Deng, Xian Qing ^a   Li, Ya Ru ^b   Zheng, Chang Ji ^b   Hong, Lan ^b   Piao, Hu Ri ^b  

^a Department of Pharmacy Jing Gangshan University College of Medicine   (China)

^b YANBIAN UNIVERSITY   (China)

Author keywords

Anti bacterial; Methicillin resistant Staphylococcus aureus; Rhodanine

Indexed keywords

(2) 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL) BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 METHYLPENTANOIC ACID; (2) 3 METHYL 2 ( 5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1EN 1 YL)BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)PENTANOIC ACID; (S)-4-MET5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1EN 1 YL)BENZYLIDENE 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)PENTANOIC ACID; 2 (5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1 EN 1 YL)BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 PHENYLPROPANOIC ACID; 2 (5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1 EN 1YL)BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 PHENYLPROPANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL )BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 PHENYLPROPANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL) BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 (1H INDOL 3 YL) PROPANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL) BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL) BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 3 METHYLBUTANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL) BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) 4 METHYLPENTANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL) BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL) METHYLPENTANOIC ACID; 2 (5 (4 (3 ([1,1' BIPHENYL] 4 YL) 3 OXOPROP 1 EN 1YL)BENZYLIDENE); 3 (1H INDOL 3 YL) 2 (5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1 EN 1 YL)BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)PROPANOIC ACID; 3 (1H INDOL 3 YL) 2 (5 (4-(3 (NAPHTHALEN 2 YL) 3 OXOPROP 1 EN 1 YL)BENZYLIDENE)4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)PROPANOIC ACID; 3 METHYL 2 ( 5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1EN 1 YL)BENZYLIDENE) 4 OXO 2 THIOXOTHOAZOLDIN 3 YL)BUTANOIC ACID; 3 METHYL 2 (5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1EN 1 YL)BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)BUTANOIC ACID; 4 METHYL 2 (5 (4 (3 (NAPHTHALEN 2 YL) 3 OXOPROP 1EN 1 YL)BENZYLIDENE) 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)PENTANOIC ACID; ANTIINFECTIVE AGENT; CHALCONE; RHODANINE; UNCLASSIFIED DRUG; 4-METHYL-2-(5-(4-(3-(NAPHTHALEN-2-YL)-3-OXOPROP-1-EN-1-YL)BENZYLIDENE)-4-OXO-2-THIOXOTHIAZOLIDIN-3-YL)PENTANOIC ACID; CHALCONE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANCE; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; RHODANINE; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84907057145     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2013.837899     Document Type: Article

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