Synthesis and bioactivity evaluation of rhodanine derivatives as potential anti-bacterial agents

European Journal of Medicinal Chemistry

Volumn 54, Issue , 2012, Pages 403-412

  Song, Ming Xia ^a   Zheng, Chang Ji ^a   Deng, Xian Qing ^a   Wang, Qing ^a   Hou, Shao Pu ^a   Liu, Ting Ting ^a   Xing, Xiao Lan ^a   Piao, Hu Ri ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

Acetic acid; Anti bacterial activity; Propanoic acid; Rhodanine

Indexed keywords

2 [5 [4 [2 (2 BROMOPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (2 BROMOPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (2 CHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (2 CHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (2 FLUOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (2 FLUOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (2,4 DICHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (2,4 DICHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (3 BROMOPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (3 BROMOPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (3 CHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (3 CHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (4 BROMOPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (4 BROMOPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (4 CHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (4 CHLOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 2 [5 [4 [2 (4 FLUOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (1H INDOL 3 YL)PROPANOIC ACID; 2 [5 [4 [2 (4 FLUOROPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIA ZOLIDIN 3 YL] 3 (4 HYDROXYPHENYL)PROPANOIC ACID; 3 (1H INDOL 3 YL) 2 [4 OXO 5 [4 (2 OXO 2 PHENYLETHOXY)BENZYLIDENE] 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; 3 (1H INDOL 3 YL) 2 [4 OXO 5 [4 [2 OXO 2 (4 TOLYL)ETHOXY]BENZYLIDENE] 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; 3 (1H INDOL3 YL) 2 [5 [4 [2 (3 METHOXYPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; 3 (1H INDOL3 YL) 2 [5 [4 [2 (4 METHOXYPHENYL) 2 OXOETHOXY]BENZYLIDENE] 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; 3 (4 HYDROXYPHENYL) 2 [4 OXO 5 [4 (2 OXO 2 PHENYLETHOXY)BENZYLIDENE] 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; 3 (4 HYDROXYPHENYL) 2 [4 OXO 5 [4 [2 OXO 2 (4 TOLYL)ETHOXY]BENZYLIDENE] 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; 3 (4 HYDROXYPHENYL) 2 [5 [4 [2 (3 METHOXYPHENYL) 2 OXOETHOXY]BENZYLIDENE] 2 THIOXOTHIAZOLIDIN 3 YL]PROPANOIC ACID; ANTIINFECTIVE AGENT; NORFLOXACIN; OXACILLIN; RHODANINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; GRAM POSITIVE BACTERIUM; INFRARED RADIATION; MASS SPECTROMETRY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-BACTERIAL AGENTS; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG RESISTANCE, MULTIPLE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; QUINOLONES; RHODANINE;

EID: 84864418734     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.05.023     Document Type: Article

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