The synthesis of phenylalanine-derived C5-substituted rhodanines and their activity against selected methicillin-resistant Staphylococcus aureus (MRSA) strains

European Journal of Medicinal Chemistry

Volumn 45, Issue 12, 2010, Pages 5827-5832

  Hardej, Diane ^a   Ashby Jr , Charles R ^a   Khadtare, Nikhil S ^a   Kulkarni, Shridhar S ^a   Singh, Satyakam ^a   Talele, Tanaji T ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

MRSA; Rhodanine; Serum

Indexed keywords

2 (5 (3 PHENOXYBENZYLIDENE)4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; 2 (5 (4 METHOXYBENZYLIDENE)4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; 2 (5 (4 QUINOLINYLIDENE)4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID QUINOLIN 4 YL; 2 (5 (CINNAMYLIDENE)4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID STYRYL; 2 (5 (CYCLOHEXYLIDENE)4 OXO 2 THIOXOTHIAZOLIDIN 3 YL)ACETIC ACID; ANTIINFECTIVE AGENT; CIPROFLOXACIN; PENICILLIN G; UNCLASSIFIED DRUG; VANCOMYCIN;

ARTICLE; BACTERIAL STRAIN; DRUG SYNTHESIS; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN;

ANTI-BACTERIAL AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PHENYLALANINE; RHODANINE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 78649333994     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.09.045     Document Type: Article

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