IFN-α exerts opposing effects on activation-induced and IL-7-induced proliferation of T cells that may impair homeostatic maintenance of CD4+T cell numbers in treated HIV infection

Journal of Immunology

Volumn 193, Issue 5, 2014, Pages 2178-2186

  Cha, Lilian ^a   De Jong, Emma ^a   French, Martyn A ^a,b   Fernandez, Sonia ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; ALPHA8 INTERFERON; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; KI 67 ANTIGEN; STAPHYLOCOCCUS ENTEROTOXIN B; STAT5 PROTEIN; UNCLASSIFIED DRUG; IFNA8 PROTEIN, HUMAN; IL7 PROTEIN, HUMAN; INTERLEUKIN 7 RECEPTOR ALPHA;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW STROMA CELL; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOLOGY; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION; VIRUS CELL INTERACTION; CELL PROLIFERATION; CLINICAL TRIAL; DRUG EFFECTS; IMMUNOLOGY; MIDDLE AGED; MULTICENTER STUDY; PATHOLOGY;

ADULT; AGED; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; HIV INFECTIONS; HUMANS; INTERFERON-ALPHA; INTERLEUKIN-7; INTERLEUKIN-7 RECEPTOR ALPHA SUBUNIT; KI-67 ANTIGEN; MALE; MIDDLE AGED; STAT5 TRANSCRIPTION FACTOR;

EID: 84907031396     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1302536     Document Type: Article

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