Interleukin-7 signalling defects in naive CD4+ T cells of HIV patients with CD4+ T-cell deficiency on antiretroviral therapy are associated with T-cell activation and senescence

AIDS

Volumn 28, Issue 6, 2014, Pages 821-830

  Tanaskovic, Sara ^a   Fernandez, Sonia ^a   Price, Patricia ^a   French, Martyn A ^a,b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ROYAL PERTH HOSPITAL   (Australia)

Author keywords

CD127; HIV; Immune activation; Interleukin 7; Senescence; Signal transducer and activator of transcription 5 phosphorylation

Indexed keywords

CD14 ANTIGEN; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HLA DR ANTIGEN; INTERLEUKIN 7; INTERLEUKIN 7 RECEPTOR; STAT5 PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CELL AGING; DOWN REGULATION; HOMEOSTASIS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INNATE IMMUNITY; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ADULT; AGED; ANTI-RETROVIRAL AGENTS; ANTIGENS, CD; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; FEMALE; HIV INFECTIONS; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-7; KI-67 ANTIGEN; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR;

EID: 84898016838     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0000000000000213     Document Type: Article

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