Glycosaminoglycan therapy prevents TGF-β1 overexpression and pathologic changes in renal tissue of long-term diabetic rats

Journal of the American Society of Nephrology

Volumn 11, Issue 12, 2000, Pages 2324-2336

  Ceol, Monica ^a,b   Gambaro, Giovanni ^a   Sauer, Ulrich ^c   Baggio, Bruno ^a   Anglani, Franca ^a   Forino, Monica ^a   Facchin, Sonia ^a,b   Bordin, Luciana ^a   Weigert, Cora ^b   Nerlich, Andreas ^c   Schleicher, Erwin D ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSAMINOGLYCAN; HEPARIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTICOAGULATION; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC NEPHROPATHY; DOSE RESPONSE; GENE OVEREXPRESSION; GLOMERULOSCLEROSIS; HISTOPATHOLOGY; IMMUNOPATHOGENESIS; IMMUNOTHERAPY; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033672331     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (3)

1. Ziyadeh FN: The extracellular matrix in diabetic nephropathy. Am J Kidney Dis 22: 736-744, 1993
2. Osterby R: Glomerular structural changes in type 1 (insulin-dependent) diabetes mellitus: Causes, consequences, and prevention. Diabetologia 35: 803-819, 1992
3. Mauer SM, Steffes MW, Ellis EN, Sutherland DN, Brown DM, Goetz FC: Structural-functional relationships in diabetic nephropathy. J Clin Invest 74: 1143-1155, 1984