Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose

American Journal of Physiology - Renal Physiology

Volumn 275, Issue 5 44-5, 1998, Pages

  Mogyorosi, Andras ^a   Ziyadeh, Fuad N ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Diabetic nephropathy; Endothelium; Epithelium; Glomerulus; Rat; Transforming growth factor

Indexed keywords

CORE PROTEIN; DECORIN; GLUCOSE; MESSENGER RNA; PROTEOGLYCAN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ENDOTHELIUM; GLOMERULUS EPITHELIUM; HYPERGLYCEMIA; KIDNEY CORTEX; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MESANGIUM; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; TISSUE INJURY;

EID: 0031788344     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1998.275.5.f827     Document Type: Article

References (32)

1. Border, W. A., N. A. Noble, T. Yamamoto, J. R. Harper, Y. Yamaguchi, M. D. Pierschbacher, and E. Rouslahti. Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease. Nature 360: 361-364, 1992.
2. Border, W. A., S. Okuda, L. R. Languino, and E. Ruoslahti. Transforming growth factor-β regulates production of proteoglycans by mesangial cells. Kidney Int. 37: 689-695, 1990.
3. Breuer, G., G. Schmidt, and H. Kresse. Non-uniform influence of transforming growth factor-β on the biosynthesis of different forms of small chondroitin sulphate/dermatan sulphate proteoglycan. Biochem. J. 269: 551-554, 1990.
4. Diamond, J. R., M. Levinson, R. Kreisberg, and S. D. Ricardo. Increased expression of decorin in experimental hydronephrosis. Kidney Int. 51: 1133-1139, 1997.
5. Goldstein, D. J., D. C. Wheeler, and D. J. Salant. Effects of omega-3 fatty acids on complement-mediated glomerular epithelial cell injury. Kidney Int. 50: 1863-1871, 1996.
6. Haverty, T., C. J. Kelly, W. H. Hines, P. S. Amenta, M. Watanabe, R. A. Harper, N. A. Kefalides, and E. G. Neilson. Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis. J. Cell Biol. 107: 1359-1368, 1988.
7. Isaka, Y., D. K. Brees, K. Ikegaya, Y. Kaneda, E. Imai, N. A. Noble, and W. A. Border. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney. Nat. Med. 2: 418-423, 1996.
8. Iwano, M., A. Kubo, T. Nishino, H. Sato, H. Nishioka, Y. Akai, H. Kurioka, Y. Fujii, M. Kanauchi, H. Shiiki, and K. Dohi. Quantification of glomerular TGF-β1 mRNA in patients with diabetes mellitus. Kidney Int. 49: 1120-1126, 1996.
9. Kahari, V. M., L. Hakkinen, J. Westermarck, and H. Larjava. Differential regulation of decorin and biglycan gene-expression by dexamethasone and retinoic acid in cultured human skin fibroblasts. J. Invest. Dermatol. 104: 503-508, 1995.
10. Kahari, V. M., H. Larjava, and J. Uitto. Differential regulation of extracellular matrix proteoglycan (PG) gene expression. Transforming growth factor-β1 up-regulates biglycan (PGI), and versican (large fibroblast PG) but down-regulates decorin (PGII) mRNA levels in human fibroblasts in culture. J. Biol. Chem. 266: 10608-10615, 1991.
11. Klein, D. J., R. M. Cohen, and Z. Rymaszewski. Proteoglycan synthesis by bovine myocardial endothelial cells is increased by long-term exposure to high concentrations of glucose. J. Cell. Physiol. 165: 493-502, 1995.
12. Mauviel, A., K. Korang, M. Santra, D. Tewari, J. Uitto, and R. V. Iozzo. Identification of a bimodal regulatory element encompassing a canonical AP-1 binding site in the proximal promoter region of the human decorin gene. J. Biol. Chem. 271: 24824-24829, 1996.
13. Mauviel, A., M. Santra, Y. Q. Chen, J. Uitto, and R. V. Iozzo. Transcriptional regulation of decorin gene expression: induction by quiescence and repression by tumor necrosis factor-α. J. Biol. Chem. 270: 11692-11700, 1995.
14. Meyuhas, O., and R. P. Perry. Construction and identification of cDNA clones for mouse ribosomal proteins: application for the study of r-protein gene expression. Gene 10: 113-129, 1980.
15. Mogyorosi, A., and F. N. Ziyadeh. Update on pathogenesis, markers, and management of diabetic nephropathy. Curr. Opin. Nephrol. Hypertens. 5: 243-253, 1996.
16. Quigg, R. J., A. V. Cybulsky, J. B. Jacobs, and D. J. Salant. Anti-Fx1A produces complement dependent cytotoxicity of glomerular epithelial cells. Kidney Int. 34: 43-52, 1988.
17. Robbins, J. R., S. P. Evanko, and K. G. Vogel. Mechanical loading and TGF-β regulate proteoglycan synthesis in tendon. Arch. Biochem. Biophys. 342: 203-211, 1997.
18. Rocco, M., Y. Chen, S. Goldfarb, and F. N. Ziyadeh. Elevated glucose stimulates TGF-β gene expression and bioactivity in proximal tubule. Kidney Int. 41: 107-114, 1992.
19. Scholzen, T., M. Solursh, S. Suzuki, R. Reiter, J. L. Morgan, A. M. Buchberg, L. D. Siracusa, and R. V. Iozzo. The murine decorin. Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation. J. Biol. Chem. 269: 28270-28281, 1994.
20. Schonherr, E., H. T. Jarvelainen, M. G. Kinsella, L. J. Sandell, and T. N. Wight. Platelet-derived growth factor and transforming growth factor-β1 differentially affect the synthesis of biglycan and decorin by monkey arterial smooth muscle cells. Arterioscler. Thromb. 13: 1026-1036, 1993.
21. Sharma, K., J. Guo, Y. Jin, and F. N. Ziyadeh. Neutralization of TGF-β by anti-TGF-β antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes 45: 522-530, 1996.
22. Sharma, K., and F. N. Ziyadeh. Renal hypertrophy is associated with upregulation of TGF-β1 gene expression in diabetic BB rat and NOD mouse. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F1094-F1101, 1994.
23. Sharma, K., F. N. Ziyadeh, B. Alzahabi, T. A. McGowan, S. Kapoor, B. R. C. Kurnik, P. B. Kurnik, and L. S. Weisberg. Increased renal production of transforming growth factor-β1 in patients with type II diabetes. Diabetes 46: 854-859, 1997.
24. Takeuchi, Y., T. Matsumoto, E. Ogata, and Y. Shishiba. Effects of transforming growth-factor-β1 and L-ascorbate on synthesis and distribution of proteoglycans in murine osteoblast-like cells. J. Bone Miner. Metab. 8: 823-830, 1993.
25. Vleming, L. J., J. J. Baelde, R. G. Westendorp, M. R. Daha, L. A. van Es, and J. A. Bruijn. Progression of chronic renal disease in humans is associated with the deposition of basement membrane components and decorin in the interstitial extracellular matrix. Clin. Nephrol. 44: 211-219, 1995.
26. Wahab, N. A., K. Harper, and R. M. Mason. Expression of extracellular matrix molecules in human mesangial cells in response to prolonged hyperglycemia. Biochem. J. 316: 985-992, 1996.
27. Westergren-Thorsson, G., P. Antonsson, A. Malmstrom, D. Heinegard, and A. Oldberg. The synthesis of a family of structurally related proteoglycans in fibroblasts is differently regulated by TGF-β. Matrix 11: 177-183, 1991.
28. Wolf, G., K. Sharma, Y. Chen, M. Ericksen, and F. N. Ziyadeh. High glucose-induced proliferation in mesangial cells is reversed by autocrine TGF-β. Kidney Int. 42: 647-656, 1992.
29. Wolf, G., F. N. Ziyadeh, G. Zahner, R. Schroeder, and R. A. K. Stahl. Angiotensin II is mitogenic for cultured rat glomerular endothelial cells. Hypertension 27: 897-905, 1996.
30. Yamamoto, T., N. A. Noble, A. H. Cohen, C. C. Nast, A. Hishida, L. I. Gold, and W. A. Border. Expression of transforming growth factor-β isoforms in human glomerular diseases. Kidney Int. 49: 461-469, 1996.
31. Ziyadeh, F. N., K. Sharma, M. Ericksen, and G. Wolf. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by activation of transforming growth factor-β. J. Clin. Invest. 93: 536-542, 1994.
32. Ziyadeh, F. N., E. R. Snipes, M. Watanabe, R. J. Alvarez, S. Goldfarb, and T. P. Haverty. High glucose induces cell hypertrophy and stimulates collagen gene transcription in proximal tubule. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F704-F714, 1990.