Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection

Journal of Virology

Volumn 88, Issue 19, 2014, Pages 11034-11044

  Channappanavar, Rudragouda ^a   Fett, Craig ^a   Zhao, Jincun ^a   Meyerholz, David K ^b   Perlman, Stanley ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DENDRITIC CELL VACCINE; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA; VACCINIA VACCINE; VIRUS ANTIBODY; EPITOPE; PEPTIDE; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; INFECTION PREVENTION; LUNG; LUNG LAVAGE; MOUSE; NONHUMAN; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SPLEEN; VIRUS LOAD; ACTIVE IMMUNIZATION; ANIMAL; BIOSYNTHESIS; CELLULAR IMMUNITY; CHEMISTRY; DENDRITIC CELL; DRUG EFFECT; GENE EXPRESSION; GENETICS; HUMAN; HUMORAL IMMUNITY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; MORTALITY; PATHOGENICITY; SURVIVAL; TRANSPLANTATION; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; EPITOPES, T-LYMPHOCYTE; FEMALE; GENE EXPRESSION; HUMANS; IMMUNITY, ACTIVE; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNIZATION; IMMUNOLOGIC MEMORY; MICE; PEPTIDES; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; SURVIVAL ANALYSIS;

EID: 84906972730     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01505-14     Document Type: Article

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