Chloroquine improved carbon tetrachloride-induced liver fibrosis through its inhibition of the activation of hepatic stellate cells: Role of autophagy

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 9, 2014, Pages 1505-1509

  He, Wei ^a   Wang, Bin ^b   Yang, Jing ^a   Zhuang, Yun ^a   Wang, Liangzhi ^a   Huang, Xiaodan ^c   Chen, Jianping ^a  

^a THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c THE SECOND AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Chloroquine; Hepatic stellate cell; Liver fibrosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA SMOOTH MUSCLE ACTIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; CHLOROQUINE; HYDROXYPROLINE; PROTEIN P62; TRANSFORMING GROWTH FACTOR BETA1; ACTIN; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN; PROTECTIVE AGENT; SMOOTH MUSCLE ACTIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BLOOD SAMPLING; CARBON TETRACHLORIDE-INDUCED LIVER FIBROSIS; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNOFLUORESCENCE; IN VIVO STUDY; LIVER FUNCTION; MALE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; STAINING; STELLATE CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; BLOOD; CHEMICALLY INDUCED; DRUG EFFECTS; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ACTINS; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; AUTOPHAGY; CARBON TETRACHLORIDE; CHLOROQUINE; HEPATIC STELLATE CELLS; HYDROXYPROLINE; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MICROTUBULE-ASSOCIATED PROTEINS; PROTECTIVE AGENTS; RATS, SPRAGUE-DAWLEY;

EID: 84906967458     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b14-00297     Document Type: Article

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