Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 305, Issue 12, 2013, Pages

  Das, Suvarthi ^a   Seth, Ratanesh Kumar ^a   Kumar, Ashutosh ^b   Kadiiska, Maria B ^b   Michelotti, Gregory ^c   Diehl, Anna Mae ^c   Chatterjee, Saurabh ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

5; 5 dimethyl 1 pyrroline N oxide nitrone adducts; CYP2E1; Cytokines; GABA A receptor associated protein; Light chain 3 isoform B; Lipid peroxidation; Tyrosine nitration

Indexed keywords

BROMODICHLOROMETHANE; CHOLINE; CYTOCHROME P450 2E1; HEAT SHOCK PROTEIN 70; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2A; PURINERGIC P2X7 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CHAPERONE-MEDIATED AUTOPHAGY; CONFOCAL LASER MICROSCOPY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEEDING; GENE DELETION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; INFLAMMATION; MALE; METABOLISM; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VITAMIN DEFICIENCY; WESTERN BLOTTING;

5,5-DIMETHYL-1-PYRROLINE N-OXIDE-NITRONE ADDUCTS; CYP2E1; CYTOKINES; GABA-A RECEPTOR-ASSOCIATED PROTEIN; LIGHT CHAIN 3 ISOFORM B; LIPID PEROXIDATION; TYROSINE NITRATION;

ANIMALS; AUTOPHAGY; CARCINOGENS; CHOLINE DEFICIENCY; CYTOCHROME P-450 CYP2E1; FATTY LIVER; GENE EXPRESSION PROFILING; HSC70 HEAT-SHOCK PROTEINS; INFLAMMATION; LIVER; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, ANIMAL; OXIDATIVE STRESS; RECEPTORS, GABA-A; RECEPTORS, PURINERGIC P2X7; TRIHALOMETHANES;

EID: 84890342238     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00235.2013     Document Type: Article

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