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Volumn 9, Issue 9, 2014, Pages

Grape Seed Proanthocyanidins (GSPs) inhibit the growth of cervical cancer by inducing apoptosis mediated by the mitochondrial pathway

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CASPASE 3; PROANTHOCYANIDIN; PROTEIN BAK; PROTEIN BCL 2; ANTINEOPLASTIC AGENT; BAK1 PROTEIN, MOUSE; BCL2 PROTEIN, MOUSE; CASP3 PROTEIN, MOUSE; GRAPE SEED EXTRACT; GRAPE SEED PROANTHOCYANIDINS;

EID: 84906965708     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107045     Document Type: Article
Times cited : (44)

References (36)
  • 3
    • 84886953875 scopus 로고    scopus 로고
    • Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix
    • Saavedra KP, Brebi PM, Roa JCS (2012) Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix. Clinical Epigenetics 4: 1-7.
    • (2012) Clinical Epigenetics , vol.4 , pp. 1-7
    • Saavedra, K.P.1    Brebi, P.M.2    Roa, J.C.S.3
  • 4
    • 77951113169 scopus 로고    scopus 로고
    • Trends in incidence and mortality rates of squamous cell carcinoma and adenocarcinoma of cervix-worldwide
    • Mathew A, George PS (2009) Trends in incidence and mortality rates of squamous cell carcinoma and adenocarcinoma of cervix-worldwide. Asian Pac J Cancer Prev 10: 645-650.
    • (2009) Asian Pac J Cancer Prev , vol.10 , pp. 645-650
    • Mathew, A.1    George, P.S.2
  • 5
    • 0042284013 scopus 로고    scopus 로고
    • Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk
    • Riboli E, Norat T (2003) Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk. The American journal of clinical nutrition 78: 559S-569S.
    • (2003) The American Journal of Clinical Nutrition , vol.78 , pp. 559S-569S
    • Riboli, E.1    Norat, T.2
  • 7
    • 77950254934 scopus 로고    scopus 로고
    • Natural polyphenols that display anticancer properties through inhibition of kinase activity
    • Lamoral-Theys D, Pottier L, Dufrasne F, Neve J, Dubois J, et al. (2010) Natural polyphenols that display anticancer properties through inhibition of kinase activity. Curr Med Chem 17: 812-825.
    • (2010) Curr Med Chem , vol.17 , pp. 812-825
    • Lamoral-Theys, D.1    Pottier, L.2    Dufrasne, F.3    Neve, J.4    Dubois, J.5
  • 8
    • 77949474775 scopus 로고    scopus 로고
    • The anticancer properties of dietary polyphenols and its relation with apoptosis
    • Fresco P, Borges F, Marques MP, Diniz C (2010) The anticancer properties of dietary polyphenols and its relation with apoptosis. Current pharmaceutical design 16: 114-134.
    • (2010) Current Pharmaceutical Design , vol.16 , pp. 114-134
    • Fresco, P.1    Borges, F.2    Marques, M.P.3    Diniz, C.4
  • 9
    • 74749104307 scopus 로고    scopus 로고
    • Current understanding of dietary polyphenols and their role in health and disease
    • Pandey KB, Rizvi SI (2009) Current understanding of dietary polyphenols and their role in health and disease. Current Nutrition & Food Science 5: 249-263.
    • (2009) Current Nutrition & Food Science , vol.5 , pp. 249-263
    • Pandey, K.B.1    Rizvi, S.I.2
  • 10
    • 84856296568 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects triggered by grape seed extract (GSE) versus epigallocatechin and procyanidins on colon cancer cell lines
    • Dinicola S, Cucina A, Pasqualato A, D'Anselmi F, Proietti S, et al. (2012) Antiproliferative and apoptotic effects triggered by grape seed extract (GSE) versus epigallocatechin and procyanidins on colon cancer cell lines. International journal of molecular sciences 13: 651-664.
    • (2012) International Journal of Molecular Sciences , vol.13 , pp. 651-664
    • Dinicola, S.1    Cucina, A.2    Pasqualato, A.3    D'Anselmi, F.4    Proietti, S.5
  • 11
    • 0042889220 scopus 로고    scopus 로고
    • Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: Relationship to decreased fat and lipid peroxidation
    • Mittal A, Elmets CA, Katiyar SK (2003) Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidation. Carcinogenesis 24: 1379-1388.
    • (2003) Carcinogenesis , vol.24 , pp. 1379-1388
    • Mittal, A.1    Elmets, C.A.2    Katiyar, S.K.3
  • 13
    • 0042889220 scopus 로고    scopus 로고
    • Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: Relationship to decreased fat and lipid peroxidation
    • Mittal A, Elmets CA, Katiyar SK (2003) Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidation. Carcinogenesis 24: 1379-1388.
    • (2003) Carcinogenesis , vol.24 , pp. 1379-1388
    • Mittal, A.1    Elmets, C.A.2    Katiyar, S.K.3
  • 14
    • 51549102594 scopus 로고    scopus 로고
    • Multi-targeted prevention and therapy of cancer by proanthocyanidins
    • Nandakumar V, Singh T, Katiyar SK (2008) Multi-targeted prevention and therapy of cancer by proanthocyanidins. Cancer letters 269: 378-387.
    • (2008) Cancer Letters , vol.269 , pp. 378-387
    • Nandakumar, V.1    Singh, T.2    Katiyar, S.K.3
  • 15
    • 3042778748 scopus 로고    scopus 로고
    • Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B
    • Vayalil PK, Mittal A, Katiyar SK (2004) Proanthocyanidins from grape seeds inhibit expression of matrix metalloproteinases in human prostate carcinoma cells, which is associated with the inhibition of activation of MAPK and NF kappa B. Carcinogenesis 25: 987-995.
    • (2004) Carcinogenesis , vol.25 , pp. 987-995
    • Vayalil, P.K.1    Mittal, A.2    Katiyar, S.K.3
  • 17
    • 55949101361 scopus 로고    scopus 로고
    • Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells
    • Kaur M, Mandair R, Agarwal R, Agarwal C (2008) Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells. Nutrition and cancer 60 Suppl 1: 2-11.
    • (2008) Nutrition and Cancer , vol.60 , pp. 2-11
    • Kaur, M.1    Mandair, R.2    Agarwal, R.3    Agarwal, C.4
  • 18
    • 77949717864 scopus 로고    scopus 로고
    • Proanthocyanidins Inhibit In vitro and In vivo Growth of Human Non-Small Cell Lung Cancer Cells by Inhibiting the Prostaglandin E2 and Prostaglandin E2 Receptors
    • Sharma SD, Meeran SM, Katiyar SK (2010) Proanthocyanidins Inhibit In vitro and In vivo Growth of Human Non-Small Cell Lung Cancer Cells by Inhibiting the Prostaglandin E2 and Prostaglandin E2 Receptors. Molecular cancer therapeutics 9: 569-580.
    • (2010) Molecular Cancer Therapeutics , vol.9 , pp. 569-580
    • Sharma, S.D.1    Meeran, S.M.2    Katiyar, S.K.3
  • 19
    • 80555129638 scopus 로고    scopus 로고
    • Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo
    • Singh T, Sharma SD, Katiyar SK (2011) Grape Proanthocyanidins Induce Apoptosis by Loss of Mitochondrial Membrane Potential of Human Non-Small Cell Lung Cancer Cells In Vitro and In Vivo. PloS one 6.
    • (2011) PloS One , vol.6
    • Singh, T.1    Sharma, S.D.2    Katiyar, S.K.3
  • 20
    • 84864709263 scopus 로고    scopus 로고
    • Grape proanthocyanidin inhibit pancreatic cancer cell growth in vitro and in vivo through induction of apoptosis and by targeting the PI3K/Akt pathway
    • Prasad R, Vaid M, Katiyar SK (2012) Grape proanthocyanidin inhibit pancreatic cancer cell growth in vitro and in vivo through induction of apoptosis and by targeting the PI3K/Akt pathway. PloS one 7: e43064.
    • (2012) PloS One , vol.7 , pp. e43064
    • Prasad, R.1    Vaid, M.2    Katiyar, S.K.3
  • 21
    • 84866881726 scopus 로고    scopus 로고
    • Bioactive phytochemical proanthocyanidins inhibit growth of head and neck squamous cell carcinoma cells by targeting multiple signaling molecules
    • Prasad R, Katiyar SK (2012) Bioactive phytochemical proanthocyanidins inhibit growth of head and neck squamous cell carcinoma cells by targeting multiple signaling molecules. PloS one 7: e46404.
    • (2012) PloS One , vol.7 , pp. e46404
    • Prasad, R.1    Katiyar, S.K.2
  • 22
    • 13944278899 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation
    • Roy AM, Baliga MS, Katiyar SK (2005) Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation. Mol Cancer Ther 4: 81-90.
    • (2005) Mol Cancer Ther , vol.4 , pp. 81-90
    • Roy, A.M.1    Baliga, M.S.2    Katiyar, S.K.3
  • 23
    • 78449279629 scopus 로고    scopus 로고
    • Notch1 regulates the growth of human colon cancers
    • Zhang Y, Li B, Ji ZZ, Zheng PS (2010) Notch1 regulates the growth of human colon cancers. Cancer 116: 5207-5218.
    • (2010) Cancer , vol.116 , pp. 5207-5218
    • Zhang, Y.1    Li, B.2    Ji, Z.Z.3    Zheng, P.S.4
  • 24
    • 84906967900 scopus 로고    scopus 로고
    • Autofluorescent vesicular structures in hematoxylin and eosin stained duodenal mucosa of the domestic cat
    • Isitor GN, Rao S, Nayak SB, Sundaram V (2012) Autofluorescent vesicular structures in hematoxylin and eosin stained duodenal mucosa of the domestic cat. West Indian Veterinary Journal 9: 27-32.
    • (2012) West Indian Veterinary Journal , vol.9 , pp. 27-32
    • Isitor, G.N.1    Rao, S.2    Nayak, S.B.3    Sundaram, V.4
  • 25
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • Oltval ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death. Cell 74: 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltval, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 26
    • 0032509773 scopus 로고    scopus 로고
    • Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease
    • Kitamura Y, Shimohama S, Kamoshima W, Ota T, Matsuoka Y, et al. (1998) Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease. Brain research 780: 260-269.
    • (1998) Brain Research , vol.780 , pp. 260-269
    • Kitamura, Y.1    Shimohama, S.2    Kamoshima, W.3    Ota, T.4    Matsuoka, Y.5
  • 27
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 28
  • 29
    • 0033575255 scopus 로고    scopus 로고
    • Suicidal tendencies: Apoptotic cell death by caspase family proteinases
    • Wolf BB, Green DR (1999) Suicidal tendencies: apoptotic cell death by caspase family proteinases. Journal of Biological Chemistry 274: 20049-20052.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 20049-20052
    • Wolf, B.B.1    Green, D.R.2
  • 30
    • 33747879101 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins induce apoptosis and inhibit metastasis of highly metastatic breast carcinoma cells
    • Mantena SK, Baliga MS, Katiyar SK (2006) Grape seed proanthocyanidins induce apoptosis and inhibit metastasis of highly metastatic breast carcinoma cells. Carcinogenesis 27: 1682-1691.
    • (2006) Carcinogenesis , vol.27 , pp. 1682-1691
    • Mantena, S.K.1    Baliga, M.S.2    Katiyar, S.K.3
  • 31
    • 61349174095 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins inhibit the growth of human non-small cell lung cancer xenografts by targeting insulin-like growth factor binding protein-3, tumor cell proliferation, and angiogenic factors
    • Akhtar S, Meeran SM, Katiyar N, Katiyar SK (2009) Grape seed proanthocyanidins inhibit the growth of human non-small cell lung cancer xenografts by targeting insulin-like growth factor binding protein-3, tumor cell proliferation, and angiogenic factors. Clinical Cancer Research 15: 821-831.
    • (2009) Clinical Cancer Research , vol.15 , pp. 821-831
    • Akhtar, S.1    Meeran, S.M.2    Katiyar, N.3    Katiyar, S.K.4
  • 32
    • 0032797136 scopus 로고    scopus 로고
    • The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells
    • Ye X, Krohn R, Liu W, Joshi S, Kuszynski C, et al. (1999) The cytotoxic effects of a novel IH636 grape seed proanthocyanidin extract on cultured human cancer cells. Molecular and cellular biochemistry 196: 99-108.
    • (1999) Molecular and Cellular Biochemistry , vol.196 , pp. 99-108
    • Ye, X.1    Krohn, R.2    Liu, W.3    Joshi, S.4    Kuszynski, C.5
  • 33
    • 13444279819 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways
    • Roy AM, Baliga MS, Elmets CA, Katiyar SK (2005) Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways. Neoplasia (New York, NY) 7: 24-36.
    • (2005) Neoplasia (New York, NY) , vol.7 , pp. 24-36
    • Roy, A.M.1    Baliga, M.S.2    Elmets, C.A.3    Katiyar, S.K.4
  • 34
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, et al. (2004) Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014.
    • (2004) Science , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3    Droin, N.M.4    Newmeyer, D.D.5
  • 35
    • 25444519182 scopus 로고    scopus 로고
    • Pharmacologic modulation of glycogen synthase kinase-3b promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells
    • Tan J, Zhuang L, Leong H-S, Iyer NG, Liu ET, et al. (2005) Pharmacologic modulation of glycogen synthase kinase-3b promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer research 65: 9012-9020.
    • (2005) Cancer Research , vol.65 , pp. 9012-9020
    • Tan, J.1    Zhuang, L.2    Leong, H.-S.3    Iyer, N.G.4    Liu, E.T.5
  • 36
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.