메뉴 건너뛰기




Volumn 17, Issue 9, 2010, Pages 812-825

Natural polyphenols that display anticancer properties through inhibition of kinase activity

Author keywords

[No Author keywords available]

Indexed keywords

AURORA A KINASE; CARNOSIC ACID; CARNOSOL; COUMARIN DERIVATIVE; CURCUMIN; DELPHINIDIN; DITERPENE; EPIGALLOCATECHIN GALLATE; FLAVANOL DERIVATIVE; FLAVONOID; FLAVONOL DERIVATIVE; FLAVONOLIGNAN; GREEN TEA EXTRACT; ISOFLAVONE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOTRANSFERASE; POLO LIKE KINASE; POLYPHENOL DERIVATIVE; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; SILIBININ; STILBENE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE; TANNIN; TANNIN DERIVATIVE; UNINDEXED DRUG;

EID: 77950254934     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986710790712183     Document Type: Review
Times cited : (121)

References (107)
  • 1
    • 67649449180 scopus 로고    scopus 로고
    • Cancer prevention by tea: Animal studies, molecular mechanisms and human relevance
    • Yang, C. S.; Wang, X.; Lu, G.; Picinich, S. C. Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat. Rev. Cancer, 2009, 9, 429-439.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 429-439
    • Yang, C.S.1    Wang, X.2    Lu, G.3    Picinich, S.C.4
  • 3
    • 33750958329 scopus 로고    scopus 로고
    • New insights on the anticancer properties of dietary polyphenols
    • DOI 10.1002/med.20060
    • Fresco, P.; Borges, F.; Diniz, C.; Marques, M. P. M. New insights on the anticancer properties of dietary polyphenols. Med. Chem. Rev., 2006, 26, 747-766. (Pubitemid 44735552)
    • (2006) Medicinal Research Reviews , vol.26 , Issue.6 , pp. 747-766
    • Fresco, P.1    Borges, F.2    Diniz, C.3    Marques, M.P.M.4
  • 4
    • 43149091484 scopus 로고    scopus 로고
    • Mechanisms of combined action of different chemopreventive dietary compounds: A review
    • De Kok, T. M.; Van Breda, S. G.; Manson, M. M. Mechanisms of combined action of different chemopreventive dietary compounds: a review. Eur. J. Nutr., 2008, 47, 51-59.
    • (2008) Eur. J. Nutr. , vol.47 , pp. 51-59
    • De Kok, T.M.1    Van Breda, S.G.2    Manson, M.M.3
  • 5
    • 68949147006 scopus 로고    scopus 로고
    • Measuring and interpreting the selectivity of protein kinase inhibitors
    • Smyth, L.A.; Collins, I. Measuring and interpreting the selectivity of protein kinase inhibitors. J. Chem. Biol., 2009, 2, 131-151.
    • (2009) J. Chem. Biol. , vol.2 , pp. 131-151
    • Smyth, L.A.1    Collins, I.2
  • 6
    • 67650073265 scopus 로고    scopus 로고
    • Cell cycle kinases as therapeutic targets for cancer
    • Lapenna, S.; Giordano, A. cell cycle kinases as therapeutic targets for cancer. Nat. Rev. Drug Discov., 2009, 8, 547-566.
    • (2009) Nat. Rev. Drug Discov. , vol.8 , pp. 547-566
    • Lapenna, S.1    Giordano, A.2
  • 7
    • 69249137908 scopus 로고    scopus 로고
    • Peptide inhibitors targeting protein kinases
    • Eldar-Finkelman, H.; Eisenstein, M. Peptide inhibitors targeting protein kinases. Curr. Pharm. Res., 2009, 15, 2463-2470.
    • (2009) Curr. Pharm. Res. , vol.15 , pp. 2463-2470
    • Eldar-Finkelman, H.1    Eisenstein, M.2
  • 8
    • 65349122964 scopus 로고    scopus 로고
    • The current status of drug discovery against the human kinome
    • Eglen, R.M.; Reisine, T. The current status of drug discovery against the human kinome. Assay Drug Dev. Technol., 2009, 7, 22-43.
    • (2009) Assay Drug Dev. Technol. , vol.7 , pp. 22-43
    • Eglen, R.M.1    Reisine, T.2
  • 9
    • 70350772288 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors - A review on pharmacology, metabolism and side effects
    • Hartmann, J.T.; Haap, M.; Kopp, H.G.; Lipp, H.P. Tyrosine kinase inhibitors - A review on pharmacology, metabolism and side effects. Curr. Drug Metab., 2009, 10, 470-481.
    • (2009) Curr. Drug Metab. , vol.10 , pp. 470-481
    • Hartmann, J.T.1    Haap, M.2    Kopp, H.G.3    Lipp, H.P.4
  • 10
    • 68449096864 scopus 로고    scopus 로고
    • Small molecules aurora kinases inhibitors
    • Garuti, L.; Roberti, M.; Bottegoni, G. Small molecules aurora kinases inhibitors. Curr. Med. Chem., 2009, 16, 1949-1963.
    • (2009) Curr. Med. Chem. , vol.16 , pp. 1949-1963
    • Garuti, L.1    Roberti, M.2    Bottegoni, G.3
  • 11
    • 68049112546 scopus 로고    scopus 로고
    • Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology
    • Schöffski, P. Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. Oncologist, 2009, 14, 559-570.
    • (2009) Oncologist , vol.14 , pp. 559-570
    • Schöffski, P.1
  • 13
    • 33846531680 scopus 로고    scopus 로고
    • Modulation of protein kinase C by Curcumin; inhibition and activation switched by calcium ions
    • Mahmmoud, Y.A. Modulation of protein kinase C by Curcumin; inhibition and activation switched by calcium ions. Br. J. Pharmacol., 2007, 150, 200-208.
    • (2007) Br. J. Pharmacol. , vol.150 , pp. 200-208
    • Mahmmoud, Y.A.1
  • 14
    • 0035987830 scopus 로고    scopus 로고
    • Resveratrol modulates rat macrophage functions
    • DOI 10.1016/S1567-5769(02)00014-0, PII S1567576902000140
    • Leiro, J.; Alvarez, E.; Garcia, D.; Orallo, F. Resveratrol modulates rat macrophage functions. Int. Immunopharmacol., 2002, 2, 767-774. (Pubitemid 34603121)
    • (2002) International Immunopharmacology , vol.2 , Issue.6 , pp. 767-774
    • Leiro, J.1    Alvarez, E.2    Garcia, D.3    Orallo, F.4
  • 15
    • 0034333325 scopus 로고    scopus 로고
    • Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: Inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation
    • Stewart, J.R.; Christman, K.L.; O'Brian, C.A. Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation. Biochem. Pharmacol., 2000, 60, 1355-1359.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1355-1359
    • Stewart, J.R.1    Christman, K.L.2    O'Brian, C.A.3
  • 17
    • 2942612898 scopus 로고    scopus 로고
    • Phe nolic acid derivatives with potential anticancer properties-a structure- activity relationship study. Part 1: Methyl, propyl and octyl esters of caffeic and gallic acids
    • Fiuza, S. M.; Gomes, C.; Teixeira, L. G. ; Girao da Cruz, M. T.; Cordeiro, M. N.; Milhazes, N.; Borges, F.; Marques, M. P. M. Phe nolic acid derivatives with potential anticancer properties-a structure- activity relationship study. Part 1: Methyl, propyl and octyl esters of caffeic and gallic acids. Bioorg. Med. Chem., 2004, 12, 3581-3589.
    • (2004) Bioorg. Med. Chem. , vol.12 , pp. 3581-3589
    • Fiuza, S.M.1    Gomes, C.2    Teixeira, L.G.3    Girao Da Cruz, M.T.4    Cordeiro, M.N.5    Milhazes, N.6    Borges, F.7    Marques, M.P.M.8
  • 18
    • 0344009736 scopus 로고    scopus 로고
    • N-Caffeoyltyramine arrests growth of U937 and Jurkat cells by inhibiting protein tyrosine phosphorylation and inducing caspase-3
    • DOI 10.1016/j.canlet.2003.08.010
    • Park, J. B.; Schoene, N. N-Caffeoyltyramine arrests growth of U937 and Jurkat cells by inhibiting protein tyrosine phosphorylation and inducing caspase-3. Cancer Lett., 2003, 202, 161-171. (Pubitemid 37485889)
    • (2003) Cancer Letters , vol.202 , Issue.2 , pp. 161-171
    • Park, J.B.1    Schoene, N.2
  • 19
    • 34247898927 scopus 로고    scopus 로고
    • Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells
    • Kim, Y. M.; Hwang, J. T.; Kwak, D. W.; Lee, Y. K.; Park, O. J. Involvement of AMPK signaling cascade in capsaicin-induced apoptosis of HT-29 colon cancer cells. Ann. N. Y. Acad. Sci., 2007, 1095, 496-503.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1095 , pp. 496-503
    • Kim, Y.M.1    Hwang, J.T.2    Kwak, D.W.3    Lee, Y.K.4    Park, O.J.5
  • 20
    • 39149100314 scopus 로고    scopus 로고
    • Capsiate, a nunpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity
    • Pyun, B. J.; Choi, S.; Lee, Y.; Kim, T. W.; Min, J. K.; Kim, Y.; Kim, B. D.; Kim, J. H.; Kim, T. Y.; Kim, Y. M.; Kwon, Y. G. Capsiate, a nunpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity. Cancer Res., 2008, 68, 227-235.
    • (2008) Cancer Res. , vol.68 , pp. 227-235
    • Pyun, B.J.1    Choi, S.2    Lee, Y.3    Kim, T.W.4    Min, J.K.5    Kim, Y.6    Kim, B.D.7    Kim, J.H.8    Kim, T.Y.9    Kim, Y.M.10    Kwon, Y.G.11
  • 21
    • 0035110888 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-gingerol
    • Bode, A. M.; Ma, W. Y.; Surh, Y. J.; Dong, Z. Inhibition of epidermal growth factor-induced cell transformation and activator protein 1 activation by [6]-Gingerol. Cancer Res., 2001, 61, 850-853. (Pubitemid 32174390)
    • (2001) Cancer Research , vol.61 , Issue.3 , pp. 850-853
    • Bode, A.M.1    Ma, W.-Y.2    Surh, Y.-J.3    Dong, Z.4
  • 22
    • 40749083585 scopus 로고    scopus 로고
    • Multiple mechanisms are involved in 6-Gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells
    • Lee, S. H.; Cekanova, M.; Baek, S. J. Multiple mechanisms are involved in 6-Gingerol-induced cell growth arrest and apoptosis in human colorectal cancer cells. Mol. Carcinog., 2008, 47, 197-208.
    • (2008) Mol. Carcinog. , vol.47 , pp. 197-208
    • Lee, S.H.1    Cekanova, M.2    Baek, S.J.3
  • 23
    • 0032717520 scopus 로고    scopus 로고
    • Superoxide radical anion production is inhibited by tyrosol and p-coumaric acid in human neutrophils: Specific effect on protein kinase C activity
    • Virgili, F.; Sinibaldi, P.; Nardini, M.; Canali, R.; Fimiani, A.; DeLorenzo, A. Superoxide radical anion production is inhibited by tyrosol and p-coumaric acid in human neutrophils: specific effect on protein kinase C activity. Res. Comm. Biochem. Cell Mol. Biol., 1999, 3, 95-104.
    • (1999) Res. Comm. Biochem. Cell Mol. Biol. , vol.3 , pp. 95-104
    • Virgili, F.1    Sinibaldi, P.2    Nardini, M.3    Canali, R.4    Fimiani, A.5    DeLorenzo, A.6
  • 25
    • 55949110359 scopus 로고    scopus 로고
    • Rosmarinic acid antagonizes activator protein-1-dependent activation of cyclooxygenase-2 expression in human cancer and nonmalignant cell lines
    • Scheckel, K. A.; Degner, S. C.; Romagnolo, D. Rosmarinic acid antagonizes activator protein-1-dependent activation of cyclooxygenase-2 expression in human cancer and nonmalignant cell lines. J. Nutr., 2008, 138, 2098-2105.
    • (2008) J. Nutr. , vol.138 , pp. 2098-2105
    • Scheckel, K.A.1    Degner, S.C.2    Romagnolo, D.3
  • 28
    • 77950648920 scopus 로고    scopus 로고
    • http://dtp.nci.nih.gov/.
  • 30
    • 33745913944 scopus 로고    scopus 로고
    • Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism
    • Yip, E. C. H.; Chan, A. S. L.; Pang, H.; Tam, Y. K.; Wong, Y. H. Protocatechuic acid induces cell death in HepG2 hepatocellular carcinoma cells through a c-Jun N-terminal kinase-dependent mechanism. Cell Biol. Toxicol., 2006, 22, 293-302.
    • (2006) Cell Biol. Toxicol. , vol.22 , pp. 293-302
    • Yip, E.C.H.1    Chan, A.S.L.2    Pang, H.3    Tam, Y.K.4    Wong, Y.H.5
  • 31
    • 34247381960 scopus 로고    scopus 로고
    • Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation
    • DOI 10.1002/ijc.22571
    • Lin, H. S.; Chen, J. H.; Huang, C. C.; Wang, C. J. Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation. Int. J. Cancer, 2007, 120, 2306-2316. (Pubitemid 46642115)
    • (2007) International Journal of Cancer , vol.120 , Issue.11 , pp. 2306-2316
    • Lin, H.-H.1    Chen, J.-H.2    Huang, C.-C.3    Wang, C.-J.4
  • 32
    • 0031850754 scopus 로고    scopus 로고
    • Inhibitory effect of Pruni Cortex extract and its component, octacosyl ferulate, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two- Stage carcinogenesis in mouse skin
    • DOI 10.1002/(SICI)1099-1573(199806)12:4<261::AID-PTR290>3.0.CO;2-9
    • Yasukawa, K.; Dimitrijevic, S. M.; Evans, F. J.; Kawabata, S.; Takido, M. Inhibitory effect of Pruni cortex extract and its component, octacosyl ferulate, on tumour promotion by 12-O-tetradecanoylphorbol- 13-acetate in two-stage carcinogenesis in mouse skin. Phytoter. Res., 1998, 12, 261-265. (Pubitemid 28331460)
    • (1998) Phytotherapy Research , vol.12 , Issue.4 , pp. 261-265
    • Yasukawa, K.1    Dimitrijevic, S.M.2    Evans, F.J.3    Kawabata, S.4    Takido, M.5
  • 33
    • 60149095366 scopus 로고    scopus 로고
    • Caffeic acid, a phenolic phytochemical in coffe, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression
    • Kang, N. J.; Lee, K. W.; Shin, B. J.; Jung, S. K.; Hwang, M. K.; Bode, A. M.; Heo, Y. S.; Lee, H. J.; Dong, Z. Caffeic acid, a phenolic phytochemical in coffe, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression. Carcinogenesis, 2009, 30, 321-330.
    • (2009) Carcinogenesis , vol.30 , pp. 321-330
    • Kang, N.J.1    Lee, K.W.2    Shin, B.J.3    Jung, S.K.4    Hwang, M.K.5    Bode, A.M.6    Heo, Y.S.7    Lee, H.J.8    Dong, Z.9
  • 34
    • 31444437266 scopus 로고    scopus 로고
    • Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin
    • DOI 10.1007/s10495-005-3275-z
    • Sanchez, A. M.; Sanchez, M. G.; Malagarie-Cazenave, S.; Olea, N.; Diaz-Laviada, I. Induction of apoptosis in prostate tumor PC-3 cells and inhibition of xenograft prostate tumor growth by the vanilloid capsaicin. Apoptosis, 2006, 11, 89-99. (Pubitemid 43151647)
    • (2006) Apoptosis , vol.11 , Issue.1 , pp. 89-99
    • Sanchez, A.M.1    Sanchez, M.G.2    Malagarie-Cazenave, S.3    Olea, N.4    Diaz-Laviada, I.5
  • 35
    • 56349151331 scopus 로고    scopus 로고
    • In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway
    • Zhang, R.; Humphreys, I.; Sahu, R. P.; Shi, Y.; Srivastava, S. K. In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway. Apoptosis, 2008, 13, 1465-1478.
    • (2008) Apoptosis , vol.13 , pp. 1465-1478
    • Zhang, R.1    Humphreys, I.2    Sahu, R.P.3    Shi, Y.4    Srivastava, S.K.5
  • 37
    • 35348855249 scopus 로고    scopus 로고
    • Keratinocyte proliferation, differentiation, and apoptosis-Differential mechanisms of regulation by curcumin, EGCG and apigenin
    • Balasubramanian, S.; Eckert, R. L. Keratinocyte proliferation, differentiation, and apoptosis-Differential mechanisms of regulation by curcumin, EGCG and apigenin. Toxicol. Appl. Pharm., 2007, 224, 214-219.
    • (2007) Toxicol. Appl. Pharm. , vol.224 , pp. 214-219
    • Balasubramanian, S.1    Eckert, R.L.2
  • 38
    • 59149091041 scopus 로고    scopus 로고
    • Curcumin disrupts the mammalian target of rapamycin-raptor complex
    • Beevers, C. S.; Chen, L.; Liu, L.; Luo, Y.; Webster, N. J. G. Curcumin disrupts the mammalian target of rapamycin-raptor complex. Cancer Res., 2009, 69, 1000-1008.
    • (2009) Cancer Res. , vol.69 , pp. 1000-1008
    • Beevers, C.S.1    Chen, L.2    Liu, L.3    Luo, Y.4    Webster, N.J.G.5
  • 40
    • 51349132313 scopus 로고    scopus 로고
    • Cancer chemopreventive and therapeutical potential of resveratrol: Mechanistic perspectives
    • Kundu, J. K.; Surh, Y. J. Cancer chemopreventive and therapeutical potential of resveratrol: mechanistic perspectives. Cancer Lett., 2008, 269, 243-261.
    • (2008) Cancer Lett. , vol.269 , pp. 243-261
    • Kundu, J.K.1    Surh, Y.J.2
  • 41
    • 0030053296 scopus 로고    scopus 로고
    • Oncogene signal transduction inhibitors from medicinal plants
    • Chang, C. J.; Ashendel, C. L.; Geahlen, R. L.; Mclaughlin, J. L.; Waters, D. J. Oncogene signal transduction inhibitors from medicinal plants. In vivo, 1996, 10, 185-190. (Pubitemid 26001182)
    • (1996) In Vivo , vol.10 , Issue.2 , pp. 185-190
    • Chang, C.-J.1    Ashendel, C.L.2    Geahlen, R.L.3    Mclaughlin, J.L.4    Waters, D.J.5
  • 43
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur, J. A.; Sinclair, D. A. Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. Drug Discov., 2006, 5, 493-506.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 44
    • 55749100319 scopus 로고    scopus 로고
    • Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: A Bcl-2- and superoxide dismutase 2-dependent mechanism
    • Priego, S.; Feddi, F.; Ferrer, P.; Mena, S.; Benlloch, M.; Ortega, A.; Carretero, J.; Obrador, E.; Asensi, M.; Estrela J. M. Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: a Bcl-2- and superoxide dismutase 2-dependent mechanism. Mol. Cancer Ther., 2008; 7, 3330-3342.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3330-3342
    • Priego, S.1    Feddi, F.2    Ferrer, P.3    Mena, S.4    Benlloch, M.5    Ortega, A.6    Carretero, J.7    Obrador, E.8    Asensi, M.9    Estrela, J.M.10
  • 46
    • 36749022239 scopus 로고    scopus 로고
    • Baicalein induces cancer cell death and proliferation retardation by inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and Akt
    • Chao, J. I.; Su, W. C.; Liu, H. F. Baicalein induces cancer cell death and proliferation retardation by inhibition of CDC2 kinase and survivin associated with opposite role of p38 mitogen-activated protein kinase and Akt. Mol. Cancer Ther., 2007, 6, 3039-3048.
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 3039-3048
    • Chao, J.I.1    Su, W.C.2    Liu, H.F.3
  • 47
    • 55449124465 scopus 로고    scopus 로고
    • Luteolin, a flavonoid with potential for cancer prevention and therapy
    • Lin, Y.; Shi, R.; Wang, X.; Shen, H. M. Luteolin, a flavonoid with potential for cancer prevention and therapy. Curr. Cancer Drug Targets, 2008, 8, 634-649.
    • (2008) Curr. Cancer Drug Targets , vol.8 , pp. 634-649
    • Lin, Y.1    Shi, R.2    Wang, X.3    Shen, H.M.4
  • 48
    • 58949083755 scopus 로고    scopus 로고
    • Protein kinase C in prostate cancer and herbal products: A bioinformatics approach
    • Singh, S.; Malik, B. K.; Sharma, D. K. Protein kinase C in prostate cancer and herbal products: a bioinformatics approach. Int. J. Integrat. Biol., 2007, 1, 72-87.
    • (2007) Int. J. Integrat. Biol. , vol.1 , pp. 72-87
    • Singh, S.1    Malik, B.K.2    Sharma, D.K.3
  • 49
    • 58249129942 scopus 로고    scopus 로고
    • MKK4 is a novel target for the inhibition of tumor necrosis factor-α-induced vascular endothelial growth factor expression by myricetin
    • Kim, J. E.; Kwon, J. Y.; Lee, D. E.; Kang, N. J.; Heo, Y. S.; Lee, K. W.; Lee, H. J. MKK4 is a novel target for the inhibition of tumor necrosis factor-α-induced vascular endothelial growth factor expression by myricetin. Biochem. Pharmacol., 2009, 77, 412-421.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 412-421
    • Kim, J.E.1    Kwon, J.Y.2    Lee, D.E.3    Kang, N.J.4    Heo, Y.S.5    Lee, K.W.6    Lee, H.J.7
  • 51
    • 0035135225 scopus 로고    scopus 로고
    • (+)-Catechin inhibits intestinal tumor formation and suppresses focal adhesion kinase activation in the Min/+ Mouse
    • Weyant, M. J.; Carothers, A. M.; Dannenberg, A. J.; Bertagnolli, M. M. (+)-Catechin inhibits intestinal tumor formation and suppresses focal adhesion kinase activation in the Min/+ Mouse. Cancer Res., 2001, 61, 118-125.
    • (2001) Cancer Res. , vol.61 , pp. 118-125
    • Weyant, M.J.1    Carothers, A.M.2    Dannenberg, A.J.3    Bertagnolli, M.M.4
  • 52
    • 33645094927 scopus 로고    scopus 로고
    • Targeting multiple signalling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate
    • Khan, N.; Afaq, F.; Saleem, M.; Ahmad, N.; Mukhtar, H. Targeting multiple signalling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res., 2006, 66, 2500-2505.
    • (2006) Cancer Res. , vol.66 , pp. 2500-2505
    • Khan, N.1    Afaq, F.2    Saleem, M.3    Ahmad, N.4    Mukhtar, H.5
  • 53
    • 3042662699 scopus 로고    scopus 로고
    • Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase-pathways by tea polyphenols in human prostate cancer cells
    • Siddiqui, I. A.; Adhami, V. M.; Afaq, F.; Ahmad, N. ; Mukhtar, H. Modulation of phosphatidylinositol-3-kinase/protein kinase B- and mitogen-activated protein kinase-pathways by tea polyphenols in human prostate cancer cells. J. Cell. Biochem., 2003, 91, 232-242.
    • (2003) J. Cell. Biochem. , vol.91 , pp. 232-242
    • Siddiqui, I.A.1    Adhami, V.M.2    Afaq, F.3    Ahmad, N.4    Mukhtar, H.5
  • 55
    • 33748655440 scopus 로고    scopus 로고
    • Nutritional and chemopreventive anti-cancer agents upregulate expression of p27KipI, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells
    • Eto, I. Nutritional and chemopreventive anti-cancer agents upregulate expression of p27KipI, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells. Cancer Cell Int., 2006, 6:20.
    • (2006) Cancer Cell Int. , vol.6 , pp. 20
    • Eto, I.1
  • 56
    • 0033594891 scopus 로고    scopus 로고
    • 1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention
    • DOI 10.1073/pnas.96.13.7490
    • Zi, X.; Agarwal, R. Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: Implications for prostate cancer intervention. Proc. Natl. Acad. Sci. USA, 1999, 96, 7490-7495. (Pubitemid 29299689)
    • (1999) Proceedings of the National Academy of Sciences of the United States of America , vol.96 , Issue.13 , pp. 7490-7495
    • Zi, X.1    Agarwal, R.2
  • 57
    • 33244472101 scopus 로고    scopus 로고
    • Silymarin and Silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: A comparison of flavonone silibinin with flavonolignan mixture silymarin
    • Deep, G.; Singh, R. P.; Agarwal, C.; Kroll, D. J.; Agarwal, R. Silymarin and Silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavonone silibinin with flavonolignan mixture silymarin. Oncogene, 2009, 25, 1053-1069.
    • (2009) Oncogene , vol.25 , pp. 1053-1069
    • Deep, G.1    Singh, R.P.2    Agarwal, C.3    Kroll, D.J.4    Agarwal, R.5
  • 58
    • 59449097284 scopus 로고    scopus 로고
    • Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signalling
    • Singh, R. P.; Raina, K.; Deep, G.; Chan, D.; Agarwal, R. Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signalling. Clin. Cancer Res., 2009, 15, 613-621.
    • (2009) Clin. Cancer Res. , vol.15 , pp. 613-621
    • Singh, R.P.1    Raina, K.2    Deep, G.3    Chan, D.4    Agarwal, R.5
  • 59
    • 18844437520 scopus 로고    scopus 로고
    • Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma
    • Bonham, M.; Posakony, J.; Coleman, I.; Montgomery, B.; Simon, J.; Nelson, P. S. Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma. Clin. Cancer Res., 2005, 11, 3905-3914.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3905-3914
    • Bonham, M.1    Posakony, J.2    Coleman, I.3    Montgomery, B.4    Simon, J.5    Nelson, P.S.6
  • 60
    • 38849134933 scopus 로고    scopus 로고
    • Raf and MEK Protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine
    • Lee, K. W.; Kang, N. J.; Heo, Y. S.; Rogozin, E. A.; Pugiliese, A.; Hwang, M. K.; Bowden, G. T.; Bode, A. M.; Lee, H. J.; Dong, Z. Raf and MEK Protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine. Cancer Res., 2008, 68, 946-955.
    • (2008) Cancer Res. , vol.68 , pp. 946-955
    • Lee, K.W.1    Kang, N.J.2    Heo, Y.S.3    Rogozin, E.A.4    Pugiliese, A.5    Hwang, M.K.6    Bowden, G.T.7    Bode, A.M.8    Lee, H.J.9    Dong, Z.10
  • 61
    • 0034573074 scopus 로고    scopus 로고
    • Activation of antioxidant response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death
    • Chen, C; Yu, R.; Owuor, E. D.; Kong, A. D. Activation of antioxidant response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch. Pharm. Res., 2000, 23, 605-612.
    • (2000) Arch. Pharm. Res. , vol.23 , pp. 605-612
    • Chen, C.1    Yu, R.2    Owuor, E.D.3    Kong, A.D.4
  • 62
    • 5144220625 scopus 로고    scopus 로고
    • Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention
    • Hou, Z.; Lambert, J. D.; Chin, K. V.; Yang, C. S. Effects of tea polyphenols on signal transduction pathways related to cancer chemoprevention. Mut. Res., 2004, 555, 3-19.
    • (2004) Mut. Res. , vol.555 , pp. 3-19
    • Hou, Z.1    Lambert, J.D.2    Chin, K.V.3    Yang, C.S.4
  • 63
    • 1842424851 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway
    • Sah, J. F.; Balasubramanian, S.; Eckert, R. L.; Rorke, E. A. Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. J. Biol. Chem., 2004, 279, 12755-12762.
    • (2004) J. Biol. Chem. , vol.279 , pp. 12755-12762
    • Sah, J.F.1    Balasubramanian, S.2    Eckert, R.L.3    Rorke, E.A.4
  • 64
    • 33845636448 scopus 로고    scopus 로고
    • Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo
    • Thangapazham, R. L.; Singh, A. K.; Sharma, A.; Warren, J.; Gaddipati, J. P.; Maheshwari, R. K. Green tea polyphenols and its constituent epigallocatechin gallate inhibits proliferation of human breast cancer cells in vitro and in vivo. Cancer Lett., 2007, 245, 232-241.
    • (2007) Cancer Lett. , vol.245 , pp. 232-241
    • Thangapazham, R.L.1    Singh, A.K.2    Sharma, A.3    Warren, J.4    Gaddipati, J.P.5    Maheshwari, R.K.6
  • 65
    • 0029124096 scopus 로고
    • Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate
    • Liao, S.; Umekita, Y.; Guo, J.; Kokontis, J. M.; Hiipakka, R. A. Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate. Cancer Lett., 1995, 96, 239-243.
    • (1995) Cancer Lett. , vol.96 , pp. 239-243
    • Liao, S.1    Umekita, Y.2    Guo, J.3    Kokontis, J.M.4    Hiipakka, R.A.5
  • 66
    • 0037392942 scopus 로고    scopus 로고
    • The specificities of protein kinase inhibitors: An update
    • DOI 10.1042/BJ20021535
    • Bain, J.; McLauchlan, H.; Elliott, M.; Cohen, P. The specificities of protein kinase inhibitors: an update. Biochem. J., 2003, 371, 199-204. (Pubitemid 36458094)
    • (2003) Biochemical Journal , vol.371 , Issue.1 , pp. 199-204
    • Bain, J.1    McLauchlan, H.2    Elliott, M.3    Cohen, P.4
  • 67
    • 4444368237 scopus 로고    scopus 로고
    • Black tea polyphenol theaflavins inhibits aromatase activity and attenuate tamoxifen resistance in HER2/neu-transfected human breast cancer cells through tyrosine kinase suppression
    • Way, T. D.; Lee, H. H.; Kao, M. C.; Lin, J. K. Black tea polyphenol theaflavins inhibits aromatase activity and attenuate tamoxifen resistance in HER2/neu-transfected human breast cancer cells through tyrosine kinase suppression. Eur. J. Cancer, 2004, 40, 2165-2174.
    • (2004) Eur. J. Cancer , vol.40 , pp. 2165-2174
    • Way, T.D.1    Lee, H.H.2    Kao, M.C.3    Lin, J.K.4
  • 68
    • 0032993095 scopus 로고    scopus 로고
    • Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate
    • Liang, Y. C.; Chen, Y. C.; Lin, Y. L.; Lin-Shiau, S. Y.; Ho, C. T.; Lin, J. K. Suppression of extracellular signals and cell proliferation by the black tea polyphenol, theaflavin-3,3'-digallate. Carcinogenesis, 1999, 20, 733-736.
    • (1999) Carcinogenesis , vol.20 , pp. 733-736
    • Liang, Y.C.1    Chen, Y.C.2    Lin, Y.L.3    Lin-Shiau, S.Y.4    Ho, C.T.5    Lin, J.K.6
  • 69
    • 48649083102 scopus 로고    scopus 로고
    • Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells
    • Choi, E. J.; Kim, G. H. Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells. Phytomedecine, 2008, 15, 683-690.
    • (2008) Phytomedecine , vol.15 , pp. 683-690
    • Choi, E.J.1    Kim, G.H.2
  • 70
    • 0038308563 scopus 로고    scopus 로고
    • Effects on soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity
    • Su, S. J.; Chow, N. H.; Kung, M. L.; Hung, T. C.; Chang, K. L. Effects on soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity. Nutr. Cancer, 2003, 45, 113-123.
    • (2003) Nutr. Cancer , vol.45 , pp. 113-123
    • Su, S.J.1    Chow, N.H.2    Kung, M.L.3    Hung, T.C.4    Chang, K.L.5
  • 71
    • 0028567131 scopus 로고
    • Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein
    • Scholar, E. M.; Toews, M. L.; Inhibition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor genistein. Cancer Lett., 1994, 87, 159-162.
    • (1994) Cancer Lett. , vol.87 , pp. 159-162
    • Scholar, E.M.1    Toews, M.L.2
  • 72
    • 48749117943 scopus 로고    scopus 로고
    • Multi-targeted therapy of cancer by genistein
    • Banerjee, S.; Li, Y.; Wang, Z.; Sarkar, F. H. Multi-targeted therapy of cancer by genistein. Cancer Lett., 2008, 269, 226-242.
    • (2008) Cancer Lett. , vol.269 , pp. 226-242
    • Banerjee, S.1    Li, Y.2    Wang, Z.3    Sarkar, F.H.4
  • 73
    • 40949106128 scopus 로고    scopus 로고
    • Silibinin inhibits colorectal cancer growth by inhibiting tumor cell proliferation and angiogenesis
    • DOI 10.1158/0008-5472.CAN-07-6247
    • Singh, R. P.; Gu, M.; Agarwal, R. Silibinin Inhibits Colorectal Cancer Growth by Inhibiting Tumor Cell Proliferation and Angiogenesis. Cancer Res., 2008, 68, 2043-2050. (Pubitemid 351416592)
    • (2008) Cancer Research , vol.68 , Issue.6 , pp. 2043-2050
    • Singh, R.P.1    Gu, M.2    Agarwal, R.3
  • 74
    • 36949029439 scopus 로고    scopus 로고
    • Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft
    • DOI 10.1093/carcin/bgm218
    • Singh, R. P.; Deep, G.; Blouin, M. J.; Pollak, M. N.; Agarwal, R. Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft. Carcinogenesis, 2007, 28, 2567-2574. (Pubitemid 350238960)
    • (2007) Carcinogenesis , vol.28 , Issue.12 , pp. 2567-2574
    • Singh, R.P.1    Deep, G.2    Blouin, M.-J.3    Pollak, M.N.4    Agarwal, R.5
  • 75
    • 20144372639 scopus 로고    scopus 로고
    • Milk thistle and prostate cancer: Differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells
    • Davis-Searles, P. R.; Nakanishi, Y.; Kim, N. C.; Graf, T. N.; Oberlies, §N. H.; Wani, M. C.; Wall, M. E.; Agarwal, R.; Kroll, D. J. Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells. Cancer Res., 2005, 65, 4448-4457.
    • (2005) Cancer Res. , vol.65 , pp. 4448-4457
    • Davis-Searles, P.R.1    Nakanishi, Y.2    Kim, N.C.3    Graf, T.N.4    Oberlies, N.H.5    Wani, M.C.6    Wall, M.E.7    Agarwal, R.8    Kroll, D.J.9
  • 76
    • 0040454756 scopus 로고
    • The biosynthesis of coumarin in Melitus Alba
    • Stoker, J. R.; Bellis, D. M. The biosynthesis of coumarin in Melitus Alba. J. Biol. Chem., 1962, 237, 2303-2305.
    • (1962) J. Biol. Chem. , vol.237 , pp. 2303-2305
    • Stoker, J.R.1    Bellis, D.M.2
  • 77
    • 6944237046 scopus 로고    scopus 로고
    • Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer
    • DOI 10.2174/1381612043382693
    • Lacy, A.; O'Kennedy, R. Studies on coumarins and coumarin-related compounds to determine their therapeutic role in the treatment of cancer. Curr. Pharm. Design, 2004, 10, 3797-3811. (Pubitemid 39409871)
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.30 , pp. 3797-3811
    • Lacy, A.1    O'Kennedy, R.2
  • 79
    • 33749527183 scopus 로고    scopus 로고
    • Comparative immunomodulatory effect of scopoletin on tumoral and normal lymphocytes
    • DOI 10.1016/j.lfs.2006.06.045, PII S0024320506005200
    • Manuele, G. M.; Ferraro, G.; Arcos, M. L. B.; Lopez, P.; Cremaschi, G.; Anesini, C. Comparative immunomodulatory effect of scopoletin on tumoral and normal lymphocytes. Life Sci., 2006, 79, 2043-2048. (Pubitemid 44528585)
    • (2006) Life Sciences , vol.79 , Issue.21 , pp. 2043-2048
    • Manuele, M.G.1    Ferraro, G.2    Barreiro Arcos, M.L.3    Lopez, P.4    Cremaschi, G.5    Anesini, C.6
  • 80
    • 0033554002 scopus 로고    scopus 로고
    • Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor
    • Yang, E. B.; Zhao, Y. N. ; Zhang, K. ; Mack, P. Daphnetin, one of coumarin derivatives, is a protein kinase inhibitor. Biochem. Biophys. Res. Commun., 1999, 260, 682-685.
    • (1999) Biochem. Biophys. Res. Commun. , vol.260 , pp. 682-685
    • Yang, E.B.1    Zhao, Y.N.2    Zhang, K.3    Mack, P.4
  • 81
    • 0027438581 scopus 로고
    • Effects of tannic acid on 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C activation in NIH 3T3 cells
    • DOI 10.1016/0006-2952(93)90095-E
    • Kuo, M. L.; Wu, W. S.; Lee, C.; Lin, J. K. Effects of tannic acid on 12-Otetradecanoylphorbol-13-acetate-induced protein kinase C activation in the NIH 3T3 cells. Biochem. Pharmacol., 1993, 46, 1327-1332. (Pubitemid 23319300)
    • (1993) Biochemical Pharmacology , vol.46 , Issue.8 , pp. 1327-1332
    • Kuo, M.-L.1    Wu, W.-S.2    Lee, K.-C.3    Lin, J.-K.4
  • 82
    • 3042574709 scopus 로고    scopus 로고
    • Potential toxicity of flavonoids and other dietary phenolics: Significance for their chemopreventive and anticancer properties
    • Galati, G.; O'Brien, P. J. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic. Biol. Med., 2004, 37, 287-303.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 287-303
    • Galati, G.1    O'Brien, P.J.2
  • 84
    • 0035114407 scopus 로고    scopus 로고
    • The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor
    • DOI 10.1021/jf0009100
    • Meiers, S.; Kemény, M.; Weyand, U.; Gastpar, R.; Von Angerer, E.; Marko, D. The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. J. Agric. Food Chem., 2001, 49, 958-962. (Pubitemid 32172654)
    • (2001) Journal of Agricultural and Food Chemistry , vol.49 , Issue.2 , pp. 958-962
    • Meiers, S.1    Kemeny, M.2    Weyand, U.3    Gastpar, R.4    Von Angerer, E.5    Marko, D.6
  • 85
    • 61449168794 scopus 로고    scopus 로고
    • Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha
    • Hwang, M. K.; Kang, N. J.; Heo, Y. S.; Lee, K. W.; Lee, H. J. Fyn kinase is a direct molecular target of delphinidin for the inhibition of cyclooxygenase-2 expression induced by tumor necrosis factor-alpha. Biochem. Pharmacol., 2009, 77, 1213-1222.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 1213-1222
    • Hwang, M.K.1    Kang, N.J.2    Heo, Y.S.3    Lee, K.W.4    Lee, H.J.5
  • 86
    • 34247860702 scopus 로고    scopus 로고
    • Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2
    • Kwon, J. Y.; Lee, K. W.; Hur, H. J.; Lee, H. J. Peonidin inhibits phorbol-ester-induced COX-2 expression and transformation in JB6 P+ cells by blocking phosphorylation of ERK-1 and -2. Ann. N. Y. Acad. Sci., 2007, 1095, 513-520.
    • (2007) Ann. N. Y. Acad. Sci. , vol.1095 , pp. 513-520
    • Kwon, J.Y.1    Lee, K.W.2    Hur, H.J.3    Lee, H.J.4
  • 87
    • 49549117517 scopus 로고    scopus 로고
    • Carnosol, a dietary diterpene, display growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5′-AMP-activated protein kinase (AMPK) pathway
    • Johnson, J. J.; Syed, D. N.; Heren, C. R.; Suh, Y.; Adhami, V. M.; Mukhtar, H. Carnosol, a dietary diterpene, display growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5′-AMP-activated protein kinase (AMPK) pathway. Pharm. Res., 2008, 25, 2125-2134.
    • (2008) Pharm. Res. , vol.25 , pp. 2125-2134
    • Johnson, J.J.1    Syed, D.N.2    Heren, C.R.3    Suh, Y.4    Adhami, V.M.5    Mukhtar, H.6
  • 88
    • 33846044020 scopus 로고    scopus 로고
    • The effect of plant phenols on the expression and activity of phorbol ester-induced PKC in mouse epidermis
    • DOI 10.1016/j.tox.2006.10.001, PII S0300483X06005890
    • Szaefer, H.; Kaczmarek, J.; Rybczynska, M.; Baer-Dubowska, W. The effect of plant phenols on the expression and activity of phorbol ester-induced PKC in mouse epidermis. Toxicology, 2007, 230, 1-10. (Pubitemid 46073325)
    • (2007) Toxicology , vol.230 , Issue.1 , pp. 1-10
    • Szaefer, H.1    Kaczmarek, J.2    Rybczynska, M.3    Baer-Dubowska, W.4
  • 89
    • 33646343750 scopus 로고    scopus 로고
    • Tannic acid, a potent inhibitor of epidermal growth factor receptor tyrosine kinase
    • DOI 10.1093/jb/mvj050
    • Yang, E. B.; Wei, L.; Zhang, K.; Chen, Y. Z.; Chen, W. N. Tannic acid, a potent inhibitor of epidermal growth factor receptor tyrosine kinase. J. Biochem., 2006, 139, 495-502. (Pubitemid 43667113)
    • (2006) Journal of Biochemistry , vol.139 , Issue.3 , pp. 495-502
    • Yang, E.B.1    Wei, L.2    Zhang, K.3    Chen, Y.Z.4    Chen, W.N.5
  • 90
    • 0037698800 scopus 로고    scopus 로고
    • Inhibition of cholangiocarcinoma growth by tannic acid
    • DOI 10.1053/jhep.2003.50192
    • Marienfeld, C.; Tadlock, L.; Yamagiwa, Y.; Patel, T. Inhibition of cholangiocarcinoma growth by tannic acid. Hepatology, 2003, 37, 1097-1104. (Pubitemid 36538686)
    • (2003) Hepatology , vol.37 , Issue.5 , pp. 1097-1104
    • Marienfeld, C.1    Tadlock, L.2    Yamagiwa, Y.3    Patel, T.4
  • 91
    • 0037441423 scopus 로고    scopus 로고
    • Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2
    • Martin, S.; Favot, L.; Matz, R.; Lugnier, C.; Andriantsitihaina, R. Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2. Biochem. Pharmacol., 2003, 65, 669-675.
    • (2003) Biochem. Pharmacol. , vol.65 , pp. 669-675
    • Martin, S.1    Favot, L.2    Matz, R.3    Lugnier, C.4    Andriantsitihaina, R.5
  • 92
    • 13844272556 scopus 로고    scopus 로고
    • Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factorkappaB and c-Jun
    • Huang, S. C.; Ho, C. T.; Lin-Shiau, S. Y.; Lin, J. K. Carnosol inhibits the invasion of B16/F10 mouse melanoma cells by suppressing metalloproteinase-9 through down-regulating nuclear factorkappaB and c-Jun. Biochem. Pharmacol., 2005, 69, 221-232.
    • (2005) Biochem. Pharmacol. , vol.69 , pp. 221-232
    • Huang, S.C.1    Ho, C.T.2    Lin-Shiau, S.Y.3    Lin, J.K.4
  • 93
    • 0029885105 scopus 로고    scopus 로고
    • Inhibition by rosemary and carnosol of 7,12-dimethylbenz[a] anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation
    • DOI 10.1016/0304-3835(96)04227-9, PII S0304383596042279
    • Singletary, K.; MacDonald, C.; Wallig, M. Inhibition by rosemary and carnosol of 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation. Cancer Lett., 1996, 104, 43-48. (Pubitemid 126334309)
    • (1996) Cancer Letters , vol.104 , Issue.1 , pp. 43-48
    • Singletary, K.1    MacDonald, C.2    Wallig, M.3
  • 94
    • 0035527494 scopus 로고    scopus 로고
    • 3 and retinoic acid
    • Steiner, M.; Preil, I.; Giat, J.; Levy, J. ; Sharoni, Y. ; Danilenko, M. Carnosic acid inhibits proliferation and augments differentiation of human leukemic cells induced by 1,25-dihydroxyvitamin D3 and retinoic acid. Nutr. Cancer, 2004, 41, 135-144. (Pubitemid 34666233)
    • (2001) Nutrition and Cancer , vol.41 , Issue.1-2 , pp. 135-144
    • Steiner, M.1    Priel, I.2    Giat, J.3    Levy, J.4    Sharoni, Y.5    Danilenko, M.6
  • 95
    • 55949095821 scopus 로고    scopus 로고
    • Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
    • Reuter, S.; Eifes, S.; Dicato, M.; Aggarwal, B.B.; Diederich, M. Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem. Pharmacol., 2008, 76, 1340-1351.
    • (2008) Biochem. Pharmacol. , vol.76 , pp. 1340-1351
    • Reuter, S.1    Eifes, S.2    Dicato, M.3    Aggarwal, B.B.4    Diederich, M.5
  • 96
    • 51649120622 scopus 로고    scopus 로고
    • Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans
    • Wilson, M.A.; Rimando, A.M.; Wolkow, C.A. Methoxylation enhances stilbene bioactivity in Caenorhabditis elegans. BMC Pharmacol., 2008, 8, 15 .
    • (2008) BMC Pharmacol. , vol.8 , pp. 15
    • Wilson, M.A.1    Rimando, A.M.2    Wolkow, C.A.3
  • 97
    • 57149146175 scopus 로고    scopus 로고
    • Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene
    • Perecko, T.; Jancinova, V.; Drabikova, K.; Nosal, R.; Harmatha, J. Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene. Neuro Endocrinol. Lett., 2008, 29, 802-805.
    • (2008) Neuro Endocrinol. Lett. , vol.29 , pp. 802-805
    • Perecko, T.1    Jancinova, V.2    Drabikova, K.3    Nosal, R.4    Harmatha, J.5
  • 98
    • 57749087561 scopus 로고    scopus 로고
    • Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol
    • Pan, Z.; Agawal, A.K.; Xu, T.; Feng, Q.; Baerson, S.R.; Duke, S.O.; Rimando, A.M. Identification of molecular pathways affected by pterostilbene, a natural dimethylether analog of resveratrol. BMC Med. Genom., 2008, 1, 7.
    • (2008) BMC Med. Genom. , vol.1 , pp. 7
    • Pan, Z.1    Agawal, A.K.2    Xu, T.3    Feng, Q.4    Baerson, S.R.5    Duke, S.O.6    Rimando, A.M.7
  • 99
    • 67650105291 scopus 로고    scopus 로고
    • Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells
    • Pan, M.H.; Chiou, Y.S.; Chen, W.J.; Wang, J.M.; Badmaev, V.; Ho, C.T. Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. Carcinogenesis, 2009, 30, 1234-1242.
    • (2009) Carcinogenesis , vol.30 , pp. 1234-1242
    • Pan, M.H.1    Chiou, Y.S.2    Chen, W.J.3    Wang, J.M.4    Badmaev, V.5    Ho, C.T.6
  • 102
    • 64249115003 scopus 로고    scopus 로고
    • Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7′-azaisoindigo derivatives substituted by Sonogashira cross-coupling
    • Bouchikhi, F.; Anizon, F.; Moreau, P. Synthesis, kinase inhibitory potencies and in vitro antiproliferative activity of isoindigo and 7′-azaisoindigo derivatives substituted by Sonogashira cross-coupling. Eur. J. Med. Chem., 2009, 44, 2705-2710.
    • (2009) Eur. J. Med. Chem. , vol.44 , pp. 2705-2710
    • Bouchikhi, F.1    Anizon, F.2    Moreau, P.3
  • 104
    • 67849097677 scopus 로고    scopus 로고
    • Safety of multitargeted kinase inhibitors as monotherapy treatment of cancer: A systematic review of the literature
    • Crean, S.; Boyd, D.M.; Sercus, B.; Lahn, M. Safety of multitargeted kinase inhibitors as monotherapy treatment of cancer: a systematic review of the literature. Curr. Drug Saf., 2009, 4, 143-154.
    • (2009) Curr. Drug Saf. , vol.4 , pp. 143-154
    • Crean, S.1    Boyd, D.M.2    Sercus, B.3    Lahn, M.4
  • 105
    • 0033003511 scopus 로고    scopus 로고
    • Food, nutrition, and the prevention of cancer: A global perspective
    • American Institute of Cancer Research/World Cancer Research Fund, American Institute for Cancer Research, 1997
    • Glade, M.J. Food, nutrition, and the prevention of cancer: a global perspective. American Institute of Cancer Research/World Cancer Research Fund, American Institute for Cancer Research, 1997. Nutrition, 1999, 15, 523-526.
    • (1999) Nutrition , vol.15 , pp. 523-526
    • Glade, M.J.1
  • 106
    • 34047192180 scopus 로고    scopus 로고
    • Imatinib: A review of its use in the management of gastrointestinal stromal tumours
    • DOI 10.2165/00003495-200767050-00012
    • Siddiiqui, M. A. A.; Scott, L. J. Imatinib - a review of its use in the management of gastrointestinal stromal tumors. Drugs 2007, 67, 805-820. (Pubitemid 46535650)
    • (2007) Drugs , vol.67 , Issue.5 , pp. 805-820
    • Siddiqui, M.A.A.1    Scott, L.J.2
  • 107
    • 33646348964 scopus 로고    scopus 로고
    • Kinase inhibitors: Vice becomes virtue
    • DOI 10.1016/j.ccr.2006.05.002, PII S1535610806001206
    • Vogt, P. K.; Kang, S. Kinase inhibitors: vice becomes virtue. Cancer Cell, 2006, 9, 327-328. (Pubitemid 43668736)
    • (2006) Cancer Cell , vol.9 , Issue.5 , pp. 327-328
    • Vogt, P.K.1    Kang, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.