FADD is essential for glucose uptake and survival of thymocytes

Biochemical and Biophysical Research Communications

Volumn 451, Issue 2, 2014, Pages 202-207

  Zhang, Xiang Yu ^a   Yang, Bing Ya ^a   Wang, Jia Yu ^a   Mo, Xuan ^a   Zhang, Jing ^a   Hua, Zi Chun ^a,b  

^a NANJING UNIVERSITY   (China)

^b Jiangsu TargetPharma Laboratories Inc   (China)

Author keywords

Akt; FADD; Glucose uptake; Glut1; Thymocytes

Indexed keywords

FAS ASSOCIATED DEATH DOMAIN PROTEIN; GLUCOSE TRANSPORTER 1; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; CELL COUNT; CELL SURVIVAL; CONTROLLED STUDY; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; THYMOCYTE;

MUS;

AKT; FADD; GLUCOSE UPTAKE; GLUT1; THYMOCYTES;

ANIMALS; APOPTOSIS; BIOLOGICAL TRANSPORT, ACTIVE; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 84906939155     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.092     Document Type: Article

References (32)

1. A.C. Carpenter, and R. Bosselut Decision checkpoints in the thymus Nat. Immunol. 11 2010 666 673
2. A.M. Kruisbeek, M.C. Haks, M. Carleton, A.M. Michie, J.C. Zuniga-Pflucker, and D.L. Wiest Branching out to gain control: how the pre-TCR is linked to multiple functions Immunol. Today 21 2000 637 644
3. K.A. Hogquist, T.A. Baldwin, and S.C. Jameson Central tolerance: Learning self-control in the thymus Nat. Rev. Immunol. 5 2005 772 782
4. M. Ciofani, and J.C. Zuniga-Pflucker Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism Nat. Immunol. 6 2005 881 888
5. K. Gottlob, N. Majewski, S. Kennedy, E. Kandel, R.B. Robey, and N. Hay Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase Genes Dev. 15 2001 1406 1418
6. D.R. Plas, S. Talapatra, A.L. Edinger, J.C. Rathmell, and C.B. Thompson Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology J. Biol. Chem. 276 2001 12041 12048
7. J.C. Rathmell, C.J. Fox, D.R. Plas, P.S. Hammerman, R.M. Cinalli, and C.B. Thompson Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival Mol. Cell. Biol. 23 2003 7315 7328
8. R. Chakrabarti, C.Y. Jung, T.P. Lee, H. Liu, and B.K. Mookerjee Changes in glucose transport and transporter isoforms during the activation of human peripheral blood lymphocytes by phytohemagglutinin J. Immunol. 152 1994 2660 2668
9. Q. Yu, B. Erman, A. Bhandoola, S.O. Sharrow, and A. Singer In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells J. Exp. Med. 197 2003 475 487
10. L. Swainson, S. Kinet, N. Manel, J.L. Battini, M. Sitbon, and N. Taylor Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis Proc. Natl. Acad. Sci. U.S.A. 102 2005 12867 12872
11. H.L. Wieman, J.A. Wofford, and J.C. Rathmell Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking Mol. Biol. Cell 18 2007 1437 1446
12. M.M. Juntilla, J.A. Wofford, M.J. Birnbaum, J.C. Rathmell, and G.A. Koretzky Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation Proc. Natl. Acad. Sci. U.S.A. 104 2007 12105 12110
13. C. Mao, E.G. Tili, M. Dose, M.C. Haks, S.E. Bear, I. Maroulakou, K. Horie, G.A. Gaitanaris, V. Fidanza, T. Ludwig, D.L. Wiest, F. Gounari, and P.N. Tsichlis Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition J. Immunol. 178 2007 5443 5453
14. L. Xue, L. Chiang, C. Kang, and A. Winoto The role of the PI3K-AKT kinase pathway in T-cell development beyond the beta checkpoint Eur. J. Immunol. 38 2008 3200 3207
15. D.R. Beisner, I.H. Chu, A.F. Arechiga, S.M. Hedrick, and C.M. Walsh The requirements for Fas-associated death domain signaling in mature T cell activation and survival J. Immunol. 171 2003 247 256
16. H. Wajant, E. Haas, R. Schwenzer, F. Muhlenbeck, S. Kreuz, G. Schubert, M. Grell, C. Smith, and P. Scheurich Inhibition of death receptor-mediated gene induction by a cycloheximide-sensitive factor occurs at the level of or upstream of Fas-associated death domain protein (FADD) J. Biol. Chem. 275 2000 24357 24366
17. H.Z. Imtiyaz, S. Rosenberg, Y. Zhang, Z.S. Rahman, Y.J. Hou, T. Manser, and J. Zhang The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells J. Immunol. 176 2006 6852 6861
18. C. Yao, H. Zhuang, P. Du, W. Cheng, B. Yang, S. Guan, Y. Hu, D. Zhu, M. Christine, L. Shi, and Z.C. Hua Role of Fas-associated death domain-containing protein (FADD) phosphorylation in regulating glucose homeostasis: From proteomic discovery to physiological validation Mol. Cell. Proteomics 12 2013 2689 2700
19. N.H. Kabra, C. Kang, L.C. Hsing, J. Zhang, and A. Winoto T cell-specific FADD-deficient mice: FADD is required for early T cell development Proc. Natl. Acad. Sci. U.S.A. 98 2001 6307 6312
20. M. Panattoni, F. Sanvito, V. Basso, C. Doglioni, G. Casorati, E. Montini, J.R. Bender, A. Mondino, and R. Pardi Targeted inactivation of the COP9 signalosome impairs multiple stages of T cell development J. Exp. Med. 205 2008 465 477
21. W. Cheng, L. Wang, R. Zhang, P. Du, B. Yang, H. Zhuang, B. Tang, C. Yao, M. Yu, Y. Wang, J. Zhang, W. Yin, J. Li, W. Zheng, M. Lu, and Z. Hua Regulation of protein kinase C inactivation by Fas-associated protein with death domain J. Biol. Chem. 287 2012 26126 26135
22. M.L. Deftos, Y.W. He, E.W. Ojala, and M.J. Bevan Correlating notch signaling with thymocyte maturation Immunity 9 1998 777 786
23. M.G. Vander Heiden, D.R. Plas, J.C. Rathmell, C.J. Fox, M.H. Harris, and C.B. Thompson Growth factors can influence cell growth and survival through effects on glucose metabolism Mol. Cell. Biol. 21 2001 5899 5912
24. A.M. Shannon, B.A. Telfer, P.D. Smith, M. Babur, A. Logie, R.W. Wilkinson, C. Debray, I.J. Stratford, K.J. Williams, and S.R. Wedge The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts Clin. Cancer Res. 15 2009 6619 6629
25. C.Y. Lin, S.C. Hsu, H.S. Lee, S.H. Lin, C.S. Tsai, S.M. Huang, C.C. Shih, and Y.J. Hsu Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure J. Vasc. Surg. 57 2013 475 485
26. X. Zhang, X. Dong, H. Wang, J. Li, B. Yang, J. Zhang, and Z.C. Hua FADD regulates thymocyte development at the beta-selection checkpoint by modulating Notch signaling Cell Death Dis. 5 2014 e1273
27. J.C. Rathmell, M.G. Vander Heiden, M.H. Harris, K.A. Frauwirth, and C.B. Thompson In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability Mol. Cell 6 2000 683 692
28. S.R. Jacobs, C.E. Herman, N.J. Maciver, J.A. Wofford, H.L. Wieman, J.J. Hammen, and J.C. Rathmell Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways J. Immunol. 180 2008 4476 4486
29. T. Palomero, M.L. Sulis, M. Cortina, P.J. Real, K. Barnes, M. Ciofani, E. Caparros, J. Buteau, K. Brown, S.L. Perkins, G. Bhagat, A.M. Agarwal, G. Basso, M. Castillo, S. Nagase, C. Cordon-Cardo, R. Parsons, J.C. Zuniga-Pflucker, M. Dominguez, and A.A. Ferrando Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia Nat. Med. 13 2007 1203 1210
30. D. Guo, Q. Teng, and C. Ji NOTCH and phosphatidylinositide 3-kinase/phosphatase and tensin homolog deleted on chromosome ten/AKT/mammalian target of rapamycin (mTOR) signaling in T-cell development and T-cell acute lymphoblastic leukemia Leuk. Lymphoma 52 2011 1200 1210
31. E.D. Motley, S.M. Kabir, C.D. Gardner, K. Eguchi, G.D. Frank, T. Kuroki, M. Ohba, T. Yamakawa, and S. Eguchi Lysophosphatidylcholine inhibits insulin-induced Akt activation through protein kinase C-alpha in vascular smooth muscle cells Hypertension 39 2002 508 512
32. J. Freire-Moar, H. Cherwinski, F. Hwang, J. Ransom, and D. Webb Expression of protein kinase C isoenzymes in thymocyte subpopulations and their differential regulation J. Immunol. 147 1991 405 409