Oligodendrocyte gap junction loss and disconnection from reactive astrocytes in multiple sclerosis gray matter

Journal of Neuropathology and Experimental Neurology

Volumn 73, Issue 9, 2014, Pages 865-879

  Markoullis, Kyriaki ^a   Sargiannidou, Irene ^a   Schiza, Natasa ^a   Roncaroli, Federico ^b   Reynolds, Richard ^b   Kleopa, Kleopas A ^a  

^a CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS   (Cyprus)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Astrocytes; Connexins; Demyelination; Gray matter; Multiple sclerosis; Oligodendrocytes

Indexed keywords

CONNEXIN 30; CONNEXIN 32; CONNEXIN 43; CONNEXIN 47; MESSENGER RNA; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; GAP JUNCTION PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; LEUKOCYTE ANTIGEN; NERVE PROTEIN; OLIG2 PROTEIN, HUMAN;

ADULT; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN CORTEX LESION; BRAIN TISSUE; CELL ACTIVATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE DURATION; FEMALE; GAP JUNCTION; GRAY MATTER; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MACROPHAGE ACTIVATION; MALE; MICROGLIA; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; OLIGODENDROCYTE PRECURSOR CELL; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REMYELINIZATION; AGED; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PLAQUE, AMYLOID; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ASTROCYTES; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CONNEXINS; FEMALE; GAP JUNCTIONS; GLIAL FIBRILLARY ACIDIC PROTEIN; GRAY MATTER; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; PLAQUE, AMYLOID; RNA, MESSENGER;

EID: 84906937623     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0000000000000106     Document Type: Article

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