Extensive cortical inflammation is associated with epilepsy in multiple sclerosis

Journal of Neurology

Volumn 255, Issue 4, 2008, Pages 581-586

  Calabrese, M ^a   De Stefano, N ^b   Atzori, M ^a   Bernardi, V ^a   Mattisi, I ^a   Barachino, L ^c   Rinaldi, L ^a   Morra, A ^c   McAuliffe, M M J ^d   Perini, P ^a   Battistin, L ^a,b,c,d,e   Gallo, P ^a  

^a UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c Neuroradiology Unit   (Italy)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e IRCCS SAN CAMILLO HOSPITAL   (Italy)

Author keywords

Cortical lesions; Epilepsy; Multiple sclerosis

Indexed keywords

ADULT; ARTICLE; BRAIN CORTEX; DISEASE ASSOCIATION; ENCEPHALITIS; EPILEPSY; FEMALE; HUMAN; INFLAMMATORY DISEASE; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; SEIZURE;

ADULT; BRAIN; BRAIN MAPPING; CAUSALITY; COMORBIDITY; DISEASE PROGRESSION; ELECTROENCEPHALOGRAPHY; ENCEPHALITIS; EPILEPSY; FEMALE; HUMANS; ITALY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; PREDICTIVE VALUE OF TESTS; PREVALENCE; SEVERITY OF ILLNESS INDEX;

EID: 42549167642     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-008-0752-7     Document Type: Article

References (27)

1. Spatt J, Chaix R, Mamoli B (2001) Epileptic and non-epileptic seizures in multiple sclerosis. J Neurol 248:2-9
2. Ghezzi A, Montanini R, Basso PF, et al. (1990) Epilepsy in multiple sclerosis. Eur Neurol 30:218-223
3. Engelsen BA, Gronning M (1997) Epileptic seizures in patients with multiple sclerosis. Is the prognosis of epilepsy underestimated? Seizure 6:377-382
4. Moreau TH, Sochurkova D, Lemesle M, et al. (1998) Epilepsy in patients with multiple sclerosis: radiological-clinical correlations. Epilepsia 39:893-896
5. Hauser WA, Annegers JF (1993) Epidemiology of epilepsy. In: Laidlaw J, et al. (eds) A textbook of epilepsy. Churchill Livingstone, Edinburgh, pp 23-45
6. Kinnunen E, Wikstrom J (1986) Prevalence and prognosis of epilepsy in patients with multiple sclerosis. Epilepsia 27(6):729-733
7. Garcia-Asensio S, Lopez del Val J, Barrena R, et al. (1997) Epilepsy as the first sign of multiple sclerosis. Rev Neurol 25(137):80-83 (in Spanish)
8. Spatt J, Goldenberg G, Mamoli B (1994) Simple dysphasic seizures as the sole manifestation of relapse in multiple sclerosis. Epilepsia 35(6):1342-1345
9. Poser CM, Brinar VV (2003) Epilepsy and multiple sclerosis. Epilepsy Behav 4(1):6-12 (Review)
10. Truyen L, Barkhof F, Frequin ST, et al. (1996) Magnetic resonance imaging of epilepsy in multiple sclerosis: a case control study. Implications for treatment trials with 4-aminopyridine. Mult Scler 1(4):213-217
11. Thompson AJ, Kermode AG, Moseley IF, et al. (1993) Seizures due to multiple sclerosis: seven patients with MRI correlations. J Neurol Neurosurg Psychiatry 56(12):1317-1320
12. Peterson JW, Bo L, Mork S, Chang A, Trapp BD (2001) Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Ann Neurol 50(3):389-400
13. Kutzelnigg A, Lucchinetti CF, Stadelmann C, Bruck W, Rauschka H, Bergmann M, et al. (2005) Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 128(Pt 11):2705-2712
14. Kidd D, Barkhof F, McConnel R, et al. (1999) Cortical lesions in multiple sclerosis. Brain 122:17-26
15. Geurts JJ, Bo L, Pouwels PJ, Castelijns JA, et al. (2005) Cortical lesions in multiple sclerosis: combined post-mortem MR imaging and histopathology. Am J Neuroradiol 26(3):572-577
16. Geurts JJ, Pouwels PJ, Uitdehaag BM, et al. (2005) Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging. Radiology 236(1):254-260
17. Wattjes MP, Lutterbey GG, Gieseke J, Traber F, Klotz L, Schmidt S, Schild HH (2007) Double inversion recovery brain imaging at 3T: diagnostic value in the detection of multiple sclerosis lesions. Am J Neuroradiol 28(1):54-59
18. Rugg-Gunn FJ, Boulby PA, Symms MR, Barker GJ, Duncan JS (2006) Imaging the neocortex in epilepsy with double inversion recovery imaging. Neuroimage 31(1):39-50
19. McDonald WI, Compston A, Edan G, et al. (2001) Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 50:121-122
20. Polman CH, Reingold SC, Edan G, et al. (2005) Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 58(6):840-846 (Review)
21. Calabrese M, De Stefano N, Atzori M, Bernardi V, Mattisi I, Barachino L, Morra A, Rinaldi L, Romualdi C, Perini P, Battistin L, Gallo P (2007) Cortical inflammatory lesions, as detected by Double Inversion Recovery MR imaging, can be detected early and are clinically relevant in Multiple Sclerosis. Arch Neurol 64(10):1416-1422
22. Pham DL, Xu C, Prince JL (2001) A Survey of Current Methods in Medical Image Segmentation, Technical Report JHU/ECE 99-01 (Baltimore: Department of Electrical and Computer Engineering, The Johns Hopkins University)
23. Bo L, Geurts JJ, Mork SJ, van der Valk P (2006) Grey matter pathology in multiple sclerosis. Acta Neurol Scand Supp 183:48-50 (Review)
24. Kutzelnigg A, Lassmann H (2005) Cortical lesions and brain atrophy in MS. J Neurol Sci 233(1-2):55-59 (Review)
25. Calabrese M, Atzori M, Bernardi V, Morra A, Romualdi C, Rinaldi L, McAuliffe MJ, Barachino L, Perini P, Fischl B, Battistin L, Gallo P (2007) Cortical atrophy is relevant in multiple sclerosis at clinical onset. J Neurol 254(9):1212-1220
26. Turetschek K, Wunderbaldinger P, Bankier AA, Zontsich T, Graf O, Mallek R, Hittmair K (1998) Double inversion recovery imaging of the brain: initial experience and comparison with fluid attenuated inversion recovery imaging. Magn Reson Imaging 16(2):127-135
27. Ranzato F, Perini P, Tzintzeva E, et al. (2003) Increasing frequency of multiple sclerosis in Padova, Italy: a 30 year epidemiological survey. Mult Scler 9(4):387-392