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Volumn 22, Issue 17, 2014, Pages 4566-4571
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Identification of novel inhibitors of phospho-MurNAc-pentapeptide translocase MraY from library screening: Isoquinoline alkaloid michellamine B and xanthene dye phloxine B
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Author keywords
Antibacterial; Enzyme inhibition; Michellamine B; Peptidoglycan biosynthesis; Translocase MraY
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Indexed keywords
MICHELLAMINE B;
PENTAPEPTIDE;
PHLOXINE;
PHOSPHO N ACETYLMURAMOYL PENTAPEPTIDE TRANSLOCASE;
UNCLASSIFIED DRUG;
ANTIINFECTIVE AGENT;
BACTERIAL PROTEIN;
ENZYME INHIBITOR;
EOSINE BLUE;
ISOQUINOLINE DERIVATIVE;
MICHELLAMINE A;
MOLECULAR LIBRARY;
MRAY PROTEIN, BACTERIA;
NAPHTHALENE DERIVATIVE;
TRANSFERASE;
ANTIMICROBIAL ACTIVITY;
AQUIFEX AEOLICUS;
ARTICLE;
BACILLUS SUBTILIS;
BACTERIAL GROWTH;
BINDING AFFINITY;
BINDING SITE;
CONCENTRATION RESPONSE;
CRYSTAL STRUCTURE;
DRUG DETERMINATION;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME ACTIVE SITE;
ESCHERICHIA COLI;
HYDROPHOBICITY;
IC 50;
LIGAND BINDING;
MICROCOCCUS LUTEUS;
MINIMUM INHIBITORY CONCENTRATION;
NONHUMAN;
PSEUDOMONAS AERUGINOSA;
PSEUDOMONAS PUTIDA;
RADIOASSAY;
STAPHYLOCOCCUS AUREUS;
ANTAGONISTS AND INHIBITORS;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG EFFECTS;
ENZYMOLOGY;
METABOLISM;
MICROBIAL SENSITIVITY TEST;
MOLECULAR LIBRARY;
PHARMACOLOGY;
STRUCTURE ACTIVITY RELATION;
SYNTHESIS;
AQUIFEX AEOLICUS;
BACILLUS SUBTILIS;
ESCHERICHIA COLI;
ANTI-BACTERIAL AGENTS;
BACILLUS SUBTILIS;
BACTERIAL PROTEINS;
DOSE-RESPONSE RELATIONSHIP, DRUG;
ENZYME INHIBITORS;
EOSINE I BLUISH;
ESCHERICHIA COLI;
ISOQUINOLINES;
MICROBIAL SENSITIVITY TESTS;
MOLECULAR STRUCTURE;
NAPHTHALENES;
SMALL MOLECULE LIBRARIES;
STRUCTURE-ACTIVITY RELATIONSHIP;
TRANSFERASES;
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EID: 84906935327
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2014.07.035 Document Type: Article |
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Times cited : (27)
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References (27)
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