Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention

Analytical Biochemistry

Volumn 314, Issue 2, 2003, Pages 243-252

  Zawadzke, Laura E ^a,b   Wu, Ping ^a,c   Cook, Lynda ^a   Fan, Li ^a   Casperson, Margaret ^a   Kishnani, Mona ^a   Calambur, Deepa ^a   Hofstead, Sandra J ^a   Padmanabha, Ramesh ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^c Essential Therapeutics Inc   (United States)

Author keywords

Assay development; MraY; MurG; UDP MurNAc pentapeptide

Indexed keywords

AMINO ACIDS; ESCHERICHIA COLI; PURIFICATION;

ANTIBACTERIAL INHIBITORS; ASSAY DEVELOPMENT; HIGH-THROUGHPUT SCREENS; MEMBRANE FRACTION; MRAY; MURG; THERAPEUTIC INTERVENTION; UDP-MURNAC-PENTAPEPTIDE;

ENZYMES;

BACTERIAL ENZYME; MUREIDOMYCIN A;

ANTIMICROBIAL THERAPY; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PURIFICATION; ESCHERICHIA COLI; EVALUATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCINTILLATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0037443830     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2697(02)00622-X     Document Type: Article

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